Results 31 to 40 of about 279,139 (356)

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

open access: yesFrontiers in Physiology, 2022
In the early phases of the COVID-19 pandemic, drug repurposing was widely used to identify compounds that could improve the prognosis of symptomatic patients infected by SARS-CoV-2.
Luca Sala   +13 more
doaj   +1 more source

CaMKII-dependent regulation of cardiac Na(+) homeostasis. [PDF]

open access: yes, 2014
Na(+) homeostasis is a key regulator of cardiac excitation and contraction. The cardiac voltage-gated Na(+) channel, NaV1.5, critically controls cell excitability, and altered channel gating has been implicated in both inherited and acquired arrhythmias.
Grandi, Eleonora, Herren, Anthony W
core   +2 more sources

COMPARATIVE EVALUATION OF PERMANENT CARDIAC PACING IN PACEMAKER-DEPENDENT PATIENTS WITH DIFFERENT PATTERNS OF RIGHT VENTRICLE EXCITATION

open access: yesМедицинский вестник Юга России, 2015
Purpose: comparative analysis of the effectiveness of permanent cardiac pacing and quality of life in the pacemaker-dependent chronical heart failure patients with different patterns of excitation of the right ventricle.Materials and methods: we examined
V. V. Korshunov   +2 more
doaj   +1 more source

Retrospective study of the correlation of serum potassium concentrations and the findings of heart auscultation in calves with neonatal diarrhea [PDF]

open access: yes, 1980
A retrospective study was conducted of clinical records of calves with neonatal diarrhea up to the age of 14 days concerning certain aspects of blood potassium concentration and heart rate and rhythm.
Acres, Stephen D., Klee, Wolfgang
core   +1 more source

The year in cardiology: arrhythmias and pacing. [PDF]

open access: yes, 2020
During this last year, there has been much progress with regard to anticoagulant and ablation therapy for atrial fibrillation (AF). Apart from recently issued European Society of Cardiology Guidelines for the management of patients with supraventricular ...
Calkins, H   +4 more
core   +4 more sources

ALCOHOL AND HEART RHYTHM DISORDERS

open access: yesРациональная фармакотерапия в кардиологии, 2015
Alcohol abuse and particularly extension of alcohol consumption in alcohol diseas increases the risk of cardiac arrhythmias development and aggravates existing arrhythmias.
A. O. Yusupova, A. S. Lishuta
doaj   +3 more sources

Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?

open access: yesCardiogenetics
The GPD1L gene encodes a small cytoplasmic protein that is involved in the regulation of sodium currents. Alterations in this gene have been associated with Brugada syndrome.
Andrea Greco   +10 more
doaj   +1 more source

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias

open access: yesCells, 2021
Both inherited and acquired cardiac arrhythmias are often associated with the abnormal functional expression of ion channels at the cellular level. The complex machinery that continuously traffics, anchors, organizes, and recycles ion channels at the ...
Camille E. Blandin   +3 more
doaj   +1 more source

Itraconazole-induced Torsade de Pointes in a patient receiving methadone substitution therapy [PDF]

open access: yes, 2009
Issues. Methadone, a pharmacological agent used to treat heroin dependence is relatively safe, but may cause cardiac arrhythmias in the concurrent presence of other risk factors. Approach and Key Findings.
Narayanan, S.   +2 more
core  

Andersen-Tawil syndrome: report of 3 novel mutations and high risk of symptomatic cardiac involvement. [PDF]

open access: yes, 2014
IntroductionAndersen-Tawil syndrome (ATS) is a potassium channelopathy affecting cardiac and skeletal muscle. Periodic paralysis is a presenting symptom in some patients, whereas, in others, symptomatic arrhythmias or prolongation of QT in ...
Bieganowska, Katarzyna   +11 more
core   +2 more sources

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