Results 41 to 50 of about 1,796,569 (350)

Gene Transfer of Engineered Calmodulin Alleviates Ventricular Arrhythmias in a Calsequestrin-Associated Mouse Model of Catecholaminergic Polymorphic Ventricular Tachycardia [PDF]

open access: yes, 2018
Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmogenic syndrome characterized by sudden death. There are several genetic forms of CPVT associated with mutations in genes encoding the cardiac ryanodine receptor (RyR2 ...
Belevych, Andriy E   +12 more
core   +1 more source

Cardiac Genetic Investigation of Sudden Infant and Early Childhood Death: A Study From Victims to Families

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Sudden infant death syndrome (SIDS) is the leading cause of death up to age 1. Sudden unexplained death in childhood (SUDC) is similar but affects mostly toddlers aged 1 to 4.
Maria‐Christina Kotta   +10 more
doaj   +1 more source

Genetic Basis and Molecular Biology of Cardiac Arrhythmias in Cardiomyopathies.

open access: yesCardiovascular Research, 2020
Cardiac arrhythmias are common, often the first, and sometimes the life-threatening manifestations of hereditary cardiomyopathies. Pathogenic variants in several genes known to cause hereditary cardiac arrhythmias have also been identified in the ...
A. Marian, B. Asatryan, X. Wehrens
semanticscholar   +1 more source

Endothelin and the ischaemic heart [PDF]

open access: yes, 2005
Soon after its identification as a powerful vasoconstrictor peptide, endothelin (ET-1) was implicated as a detrimental agent involved in determining the outcome of myocardial ischaemia and reperfusion.
Kane, K.A., McCabe, C., Wainwright, C.L.
core   +1 more source

Cardiac arrhythmias associated with immune checkpoint inhibitors: A comprehensive disproportionality analysis of the FDA adverse event reporting system

open access: yesFrontiers in Pharmacology, 2022
Introduction: With the widespread application of Immune checkpoint inhibitors (ICIs), it is important to explore the association between ICIs and cardiac arrhythmias and to characterize the clinical features of ICI-associated cardiac arrhythmias in real ...
Feifei Wang, Qi Wei, Xinan Wu
doaj   +1 more source

The year in cardiology: arrhythmias and pacing. [PDF]

open access: yes, 2020
During this last year, there has been much progress with regard to anticoagulant and ablation therapy for atrial fibrillation (AF). Apart from recently issued European Society of Cardiology Guidelines for the management of patients with supraventricular ...
Calkins, H   +4 more
core   +4 more sources

Associations Between Objective Sleep Characteristics From Wearable Physiologic Monitors and Incident Atrial Fibrillation

open access: yesJACC: Advances
Background: Previous research suggests a link between sleep and atrial fibrillation (AF). Most published studies are limited by the use of self-reported data or absence of information regarding sleep architecture.
Mohammad Hosein Yazdanpanah, MD   +6 more
doaj   +1 more source

Hypoglycaemia and cardiac arrhythmias in diabetes

open access: yesTherapeutic Advances in Endocrinology and Metabolism, 2020
Hypoglycaemia remains an inevitable risk in insulin-treated type 1 diabetes and type 2 diabetes and has been associated with multiple adverse outcomes.
A. Andersen   +3 more
semanticscholar   +1 more source

State-of-the-art pulsed field ablation for cardiac arrhythmias: ongoing evolution and future perspective

open access: yesEuropace
Pulsed field ablation (PFA) is an innovative approach in the field of cardiac electrophysiology aimed at treating cardiac arrhythmias. Unlike traditional catheter ablation energies, which use radiofrequency or cryothermal energy to create lesions in the ...
K. Chun   +6 more
semanticscholar   +1 more source

Andersen-Tawil syndrome: report of 3 novel mutations and high risk of symptomatic cardiac involvement. [PDF]

open access: yes, 2014
IntroductionAndersen-Tawil syndrome (ATS) is a potassium channelopathy affecting cardiac and skeletal muscle. Periodic paralysis is a presenting symptom in some patients, whereas, in others, symptomatic arrhythmias or prolongation of QT in ...
Bieganowska, Katarzyna   +11 more
core   +2 more sources

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