Results 31 to 40 of about 879,926 (306)

Mechanisms of Sudden Cardiac Death Oxidants and Metabolism

, 2017
Ventricular arrhythmia is the leading cause of sudden cardiac death (SCD). Deranged cardiac metabolism and abnormal redox state during cardiac diseases foment arrhythmogenic substrates through direct or indirect modulation of cardiac ion channel ...
Yang, Kai-Chien;Kyle, John W.;Makielski, Jonathan C.;Dudley, Samuel C., Jr., 楊鎧鍵   +1 more
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

COMPARATIVE EVALUATION OF PERMANENT CARDIAC PACING IN PACEMAKER-DEPENDENT PATIENTS WITH DIFFERENT PATTERNS OF RIGHT VENTRICLE EXCITATION

Медицинский вестник Юга России, 2015
Purpose: comparative analysis of the effectiveness of permanent cardiac pacing and quality of life in the pacemaker-dependent chronical heart failure patients with different patterns of excitation of the right ventricle.Materials and methods: we examined
V. V. Korshunov, G. V. Chudinov, V. P. Terentiev   +2 more
doaj   +1 more source

No Association Between T-peak to T-end Interval on the Resting ECG and Long-Term Incidence of Ventricular Arrhythmias Triggering ICD Interventions

Frontiers in Physiology, 2020
Background and ObjectivesPotential of using the T-peak to T-end (TpTe) interval as an electrocardiographic parameter reflecting the transmural dispersion of ventricular repolarization (TDR) to identify patients (pts.) with higher risk of malignant ...
Peter Michalek, Sasha Benjamin Hatahet, Martin Svetlosak, Peter Margitfalvi, Iveta Waczulikova, Sebastian Trnovec, Allan Böhm, Allan Böhm, Ondrej Benacka, Ondrej Benacka, Robert Hatala, Robert Hatala   +11 more
doaj   +1 more source

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

Frontiers in Physiology, 2022
In the early phases of the COVID-19 pandemic, drug repurposing was widely used to identify compounds that could improve the prognosis of symptomatic patients infected by SARS-CoV-2.
Luca Sala, Vladislav Leonov, Vladislav Leonov, Manuela Mura, Federica Giannetti, Aleksandr Khudiakov, Alessandra Moretti, Alessandra Moretti, Lia Crotti, Lia Crotti, Lia Crotti, Massimiliano Gnecchi, Massimiliano Gnecchi, Peter J. Schwartz   +13 more
doaj   +1 more source

Effects of age on the prevalence of cardiac dysrhythmias in ponies [PDF]

, 2010
This study describes the prevalence of cardiac dysrhythmias occurring over a single 24 h period in ponies and compares the heart rate and frequency of dysrhythmias in two groups of ponies of different ages Electrocardiograms were recorded using a Holter ...
Pirie, Scott; id_orcid, Rezakhani, A., Blissitt, Karen   +2 more
core  

Iron Deposition following Chronic Myocardial Infarction as a Substrate for Cardiac Electrical Anomalies: Initial Findings in a Canine Model [PDF]

, 2013
Purpose: Iron deposition has been shown to occur following myocardial infarction (MI). We investigated whether such focal iron deposition within chronic MI lead to electrical anomalies. Methods: Two groups of dogs (ex-vivo (n = 12) and in-vivo (n = 10))
Cokic Ivan, Stewart Brian, Tang, Richard, Cokic, Ivan, Wang Xunzhang, Allen M Amorn, Thajudeen, Anees, Bennett, Nathan, Richard L Q Tang, Nathan Bennett (459351), Amorn, Allen M., Sotirios A Tsaftaris, Bennett Nathan, Harlev Doron, Thajudeen Anees, Tsaftaris Sotirios A., Chugh, Sumeet S., Brian Stewart, Harlev, Doron, Allen M. Amorn (459348), Sumeet S. Chugh (215629), Tsaftaris, Sotirios A., Shehata Michael, Xunzhang Wang, Rohan Dharmakumar (459355), Chugh Sumeet S., Dharmakumar Rohan, Doron Harlev, Hsin-Jung Yang, Yang, Hsin-Jung, Amorn Allen M., Brian Stewart (459350), Wang, Xunzhang, Avinash Kali, Enzhao Liu, Nathan Bennett, Avinash Kali (459342), Warren M. Jackman (459354), Michael Shehata, Richard L. Q. Tang (459345), Tang Richard L. Q., Hsin-Jung Yang (459344), Michael Shehata (459347), Warren M Jackman, Jackman Warren M., Liu Enzhao, Liu, Enzhao, Sotirios A. Tsaftaris (459353), Ivan Cokic (459341), Rohan Dharmakumar, Stewart, Brian, Sumeet S Chugh, Ivan Cokic, Anees Thajudeen, Enzhao Liu (459349), Yang Hsin-Jung, Dharmakumar, Rohan, Jackman, Warren M., Kali, Avinash, Doron Harlev (459352), Shehata, Michael, Anees Thajudeen (459346), Kali Avinash, Xunzhang Wang (459343)   +63 more
core   +2 more sources

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Health-related internet information-seeking behaviour among patients with known or suspected cardiac arrhythmias: an exploratory cross-sectional questionnaire survey

BMC Digital Health
Background Despite the widespread availability of online health information, little is known about health-related internet information-seeking behaviour among patients with cardiac arrhythmias.
Sara Borges Antunes, Firat Duru
doaj   +1 more source

Arrhythmias May Hide a Genetic Cardiomyopathy in Left Ventricular Hypertrabeculation in Children: A Single-Center Experience

Children
Background. Left ventricular hypertrabeculation (LVHT) is a myocardial disorder with different clinical manifestations, from total absence of symptoms to heart failure, arrhythmias, sudden cardiac death (SCD), and thromboembolic events. It is challenging
Irma Battipaglia, Nicoletta Cantarutti, Marianna Cicenia, Rachele Adorisio, Virginia Battista, Anwar Baban, Massimo Stefano Silvetti, Fabrizio Drago   +7 more
doaj   +1 more source