Results 51 to 60 of about 1,796,569 (350)

Cardiac arrhythmias in low- and middle-income countries.

Cardiovascular Diagnosis and Therapy, 2020
Many low- and middle-income countries (LMICs) are undergoing an epidemiological transition. With an improvement in socioeconomic conditions and an aging population, cardiovascular diseases (CVDs), like cardiac arrhythmias, are expected to increase in ...
P. Mkoko, E. Bahiru, O. Ajijola, A. Bonny, A. Chin   +4 more
semanticscholar   +1 more source

Clinical and molecular characterization of a cardiac ryanodine receptor founder mutation causing catecholaminergic polymorphic ventricular tachycardia [PDF]

, 2015
Background Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a difficult-to-diagnose cause of sudden cardiac death (SCD). We identified a family of 1400 individuals with multiple cases of CPVT, including 36 SCDs during youth.
Allegue, Catarina, Beltran-Alvarez, Pedro, Berne, Paola, Bosch Calero, Cristina, Brugada, Josep, Brugada, Ramon, Campuzano, Oscar, Iglesias, Anna, Pérez, Carmelo, Pérez, Guillermo J., Ruiz Hernandez, Pablo M., Scornik, Fabiana S., Wangüemert, Fernando   +12 more
core   +3 more sources

Brugada Syndrome and GPD1L: Definite Genotype-Phenotype Association?

Cardiogenetics
The GPD1L gene encodes a small cytoplasmic protein that is involved in the regulation of sodium currents. Alterations in this gene have been associated with Brugada syndrome.
Andrea Greco, Estefanía Martínez-Barrios, José Cruzalegui, Sergi Cesar, Fredy Chipa, Nuria Díez-Escuté, Patricia Cerralbo, Irene Zschaeck, Paula Loredo, Georgia Sarquella-Brugada, Oscar Campuzano   +10 more
doaj   +1 more source

No Association Between T-peak to T-end Interval on the Resting ECG and Long-Term Incidence of Ventricular Arrhythmias Triggering ICD Interventions

Frontiers in Physiology, 2020
Background and ObjectivesPotential of using the T-peak to T-end (TpTe) interval as an electrocardiographic parameter reflecting the transmural dispersion of ventricular repolarization (TDR) to identify patients (pts.) with higher risk of malignant ...
Peter Michalek, Sasha Benjamin Hatahet, Martin Svetlosak, Peter Margitfalvi, Iveta Waczulikova, Sebastian Trnovec, Allan Böhm, Allan Böhm, Ondrej Benacka, Ondrej Benacka, Robert Hatala, Robert Hatala   +11 more
doaj   +1 more source

COMPARATIVE EVALUATION OF PERMANENT CARDIAC PACING IN PACEMAKER-DEPENDENT PATIENTS WITH DIFFERENT PATTERNS OF RIGHT VENTRICLE EXCITATION

Медицинский вестник Юга России, 2015
Purpose: comparative analysis of the effectiveness of permanent cardiac pacing and quality of life in the pacemaker-dependent chronical heart failure patients with different patterns of excitation of the right ventricle.Materials and methods: we examined
V. V. Korshunov, G. V. Chudinov, V. P. Terentiev   +2 more
doaj   +1 more source

Use of hiPSC-Derived Cardiomyocytes to Rule Out Proarrhythmic Effects of Drugs: The Case of Hydroxychloroquine in COVID-19

Frontiers in Physiology, 2022
In the early phases of the COVID-19 pandemic, drug repurposing was widely used to identify compounds that could improve the prognosis of symptomatic patients infected by SARS-CoV-2.
Luca Sala, Vladislav Leonov, Vladislav Leonov, Manuela Mura, Federica Giannetti, Aleksandr Khudiakov, Alessandra Moretti, Alessandra Moretti, Lia Crotti, Lia Crotti, Lia Crotti, Massimiliano Gnecchi, Massimiliano Gnecchi, Peter J. Schwartz   +13 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Remodeling of Ion Channel Trafficking and Cardiac Arrhythmias

Cells, 2021
Both inherited and acquired cardiac arrhythmias are often associated with the abnormal functional expression of ion channels at the cellular level. The complex machinery that continuously traffics, anchors, organizes, and recycles ion channels at the ...
Camille E. Blandin, Basile J. Gravez, Stéphane N. Hatem, Elise Balse   +3 more
doaj   +1 more source

Early detection of biochemically occult autonomous thyroid nodules [PDF]

, 2016
Objective: Autonomously functioning thyroid areas may be associated with subclinical or overt hyperthyroidism, but may exist even in the presence of normal TSH.
Brusca, Nunzia, Capriello, Silvia, Cellini, Miriam, Centanni, Marco, Gargano, L., Salvatori, R., Santaguida, MARIA GIULIA, Virili, Camilla   +7 more
core   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source