Results 51 to 60 of about 718,690 (296)

Perfusion of the interventricular septum during ventilation with positive end-expiratory pressure (PEEP) [PDF]

, 1991
Objective: To determine whether regional hypoperfusion of the interventricular septum occurs during ventilation with positive end-expiratory pressure. Design: Animal study. Animals: Anesthetized, closed chest dogs (n = 8).
Iber, Volker, Messmer, Konrad, Schosser, Rudolf, Schwickert, Christiane, Spengler, Peter, Weiss, Michaela, Zwißler, Bernhard   +6 more
core  

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Monitoring of Cerebral Blood Flow Autoregulation after Cardiac Arrest

Medicina
Background: Cardiac arrest remains one of the leading causes of death. After successful resuscitation of patients in cardiac arrest, post-cardiac arrest syndrome develops, part of it being an impaired cerebral blood flow autoregulation.
Rok Petrovčič, Martin Rakusa, Andrej Markota   +2 more
doaj   +1 more source

Computer simulation of platelet activation in a pulsatile ventricular assist device, through finite elements and a simplified geometry [PDF]

, 2017
Ventricular assist devices are a technological solution for patients who suffer from cardiac insufficiency and await a transplant. In this work, a new design of an implantable pulsatile blood pump is analyzed in terms of blood damage, by means of finite ...
Berli, Marcelo Eduardo, Campana, Diego Martin, Di Paolo, José, Fries, Exequiel, Ubal, Sebastian   +4 more
core  

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]

, 2014
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
A Babaev, A Bourgoin, A Combes, A Dubin, A Geppert, A Gestel van, A Perel, A Perel, A Rhodes, A Vieillard-Baron, A Vieillard-Baron, A Vieillard-Baron, A Vieillard-Baron, AE Jones, AF Connors Jr, Alexandre Mebazaa, AM Schulman, Andrew Rhodes, AP Wheeler, AS Beraud, B Bouhemad, B Lamia, B Vallet, BP Cholley, BR Soller, C Alberti, C Brun-Buisson, C Brun-Buisson, C Brun-Buisson, C Pierrakos, CA Polanczyk, Christoph Hofer, CI Pro, D Annane, D Atkins, D Backer De, D Backer De, D Backer De, D Backer De, D Backer De, D Fagnoul, D LeDoux, Daniel De Backer, DR Holmes Jr, E Kupersztych-Hagege, E Rivers, E Silva, EP Rivers, F Boissier, F Michard, F Michard, F Vallee, G Friedman, G Hernandez, G Lheritier, G Marecaux, G Tachon, GA Wanner, H Flaatten, H Zhang, H Zhang, HB Nguyen, HH Awad, I Jawad, I Salvo, I Werra de, J Bakker, J Bakker, J Creteur, J Maizel, J Mesquida, Jan Bakker, JB Hall, JD Ricard, Jean Louis Teboul, Jean Louis Vincent, JH McGowan, JJ Ronco, JL Teboul, JL Vanoverschelde, JL Vincent, JL Vincent, JL Vincent, JL Vincent, JL Vincent, JP Quenot, JP Revelly, K Bouferrache, L Jacquet, M Antonelli, M Cannesson, M Cecconi, M Cecconi, M Cecconi, M Feissel, M Howell, M Pinsky, MA Hayes, Massimo Antonelli, Maurizio Cecconi, ME Genderen van, ME Genderen van, ME Hands, ME Mikkelsen, MH Weil, MH Weil, MI Monge Garcia, MI Monge Garcia, Michael R. Pinsky, MR Pinsky, MR Shah, NJ Ekbal, O Godje, O Hamzaoui, O Taton, P Asfar, P Asfar, P Vignon, P Wacharasint, PE Marik, PT O’Gara, RA Linton, Richard Beale, RJ Goldberg, RJ Goldberg, Roman Jaeschke, RP Dellinger, RS Hotchkiss, S Harvey, S Heenen, S Magder, S Magder, S Magder, S Magder, S Marque, S Trzeciak, SA Stern, SD Murdoch, SF Nagueh, SG Sakka, SM Cain, SR Ommen, TC Jansen, TC Jansen, TC Jansen, TC Jansen, VS Edul, WH Bickell, WT Linde-Zwirble, X Monnet, X Monnet, X Monnet, X Monnet, X Monnet, X Monnet, X Monnet, Y Sakr, Y Sakr   +157 more
core   +5 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

THE ADAPTATION TO EFFORT OF THE CIRCULATORY SYSTEM AT FORWARDS RUGBY PLAYERS

Sport şi Societate, 2011
The purpose of this study is to assess the cardiovascular adaptation of forwards rugby players during effort.The results are then compared with aspects of physiological demands on elite rugby players.
Alexandru OPREAN
doaj  

Dissociation of Cerebral Blood Flow and Femoral Artery Blood Pressure Pulsatility After Cardiac Arrest and Resuscitation in a Rodent Model: Implications for Neurological Recovery. [PDF]

, 2020
Background Impaired neurological function affects 85% to 90% of cardiac arrest (CA) survivors. Pulsatile blood flow may play an important role in neurological recovery after CA.
Akbari, Yama, Bazrafkan, Afsheen, Choi, Bernard, Crouzet, Christian, Lee, Donald, Tromberg, Bruce J, Wilson, Robert H   +6 more
core   +1 more source

Patient-specific CFD simulation of intraventricular haemodynamics based on 3D ultrasound imaging [PDF]

, 2016
Background: The goal of this paper is to present a computational fluid dynamic (CFD) model with moving boundaries to study the intraventricular flows in a patient-specific framework.
Bavo, Alessandra, Degroote, Joris, Gorman, Joseph H, Gorman, Robert C, Pouch, Alison M, Segers, Patrick, Vierendeels, Jan   +6 more
core   +2 more sources