Results 61 to 70 of about 718,690 (296)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

An isolated beating pig heart platform for a comprehensive evaluation of intracardiac blood flow with 4D flow MRI: a feasibility study

European Radiology Experimental, 2019
Background Cardiac magnetic resonance imaging (MRI) in large animals is cumbersome for various reasons, including ethical considerations, costs of housing and maintenance, and need for anaesthesia.
Eva S. Peper, Alberto M. Leopaldi, Sjoerd van Tuijl, Bram F. Coolen, Gustav J. Strijkers, Jan Baan, R. Nils Planken, Arend de Weger, Aart J. Nederveen, Henk A. Marquering, Pim van Ooij   +10 more
doaj   +1 more source

POLYCYTHEMIA, CARDIAC OUTPUT AND CORONARY BLOOD FLOW [PDF]

Pediatric Research, 1977
Decreased cardiac output (CO) and systemic oxygen transport (SOT) in polycythemia (P) are attributed to increased blood viscosity and regarded as potentially harmful. Since P is common in cyanotic heart disease, we studied its effects on CO, SOT and left ventricular coronary blood flow (CBF) and oxygen transport (LVOT) in dogs with acute isovolumlc P ...
Julien I E Hoffman, Adrianta Surjadhana, Lawrence E Boerboom, Jacques Rouleau   +3 more
openaire   +1 more source

Outflow boundary conditions for 3D simulations of non-periodic blood flow and pressure fields in deformable arteries [PDF]

, 2010
The simulation of blood flow and pressure in arteries requires outflow boundary conditions that incorporate models of downstream domains. We previously described a coupled multidomain method to couple analytical models of the downstream domains with 3D ...
Figueroa, C. A., Jansen, K. E., Taylor, C. A., Vignon-Clementel, Irene   +3 more
core   +5 more sources

Re‐Awakening Public Attention to the Silent Pandemic of Cancer Among Older Adults in Low‐ and Middle‐Income Countries

Aging and Cancer, EarlyView.
ABSTRACT As global populations age, cancer is increasingly becoming a leading cause of morbidity and mortality among older adults, particularly in low‐ and middle‐income countries (LMICs). Despite accounting for the majority of new cancer cases and deaths, older individuals remain underrepresented in cancer research, clinical guidelines, and health ...
Ibrahim Bidemi Abdullateef, Sunkanmi Folorunsho, Abdulazeez Opeyemi Abdulganiyu   +2 more
wiley   +1 more source

Development of a Simple ImageJ-Based Method for Dynamic Blood Flow Tracking in Zebrafish Embryos and Its Application in Drug Toxicity Evaluation

Inventions, 2019
This study aimed to develop a simple and cost-effective method to measure blood flow in zebrafish by using an image-based approach. Three days post fertilization (dpf) zebrafish embryos were mounted with methylcellulose and subjected to video recording ...
Fiorency Santoso, Bonifasius Putera Sampurna, Yu-Heng Lai, Sung-Tzu Liang, Erwei Hao, Jung-Ren Chen, Chung-Der Hsiao   +6 more
doaj   +1 more source

Three-dimensional structure of the flow inside the left ventricle of the human heart

, 2013
The laboratory models of the human heart left ventricle developed in the last decades gave a valuable contribution to the comprehension of the role of the fluid dynamics in the cardiac function and to support the interpretation of the data obtained in ...
Cenedese, A., Espa, S., Fortini, S., Querzoli, G.   +3 more
core   +1 more source

Transdifferentiation of blood-derived human adult endothelial progenitor cells into functionally active cardiomyocytes [PDF]

, 2003
Background - Further to promoting angiogenesis, cell therapy may be an approach for cardiac regeneration. Recent studies suggest that progenitor cells can transdifferentiate into other lineages. However, the transdifferentiation potential of endothelial
Aicher, A, Badorff, C, Brandes, RP, Busse, R, Dimmeler, S, Fleming, I, Popp, R, Rupp, S, Urbich, C, Zeiher, AM   +9 more
core   +1 more source

Life‐Threatening Bradycardia in Anti‐NMDA‐Receptor Encephalitis and a Novel Use for Permanent Pacing

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Pediatric anti‐NMDA receptor encephalitis (pNMDARE) is an autoantibody‐mediated disorder that can cause severe autonomic dysfunction, including symptomatic bradycardia and asystole. Dysautonomia can last for years, making it very challenging to manage.
Sarah Tucker, Abhijit Das, Andres Jimenez, Areeba Basit, Yike Jiang, Emily A. Smitherman, Heather Van Mater, Taylor Howard, Alexander J. Sandweiss, Kristen S. Fisher   +9 more
wiley   +1 more source

The Flow of Blood Supplying the Cardiac Atria

Experimental Biology and Medicine, 1946
SummaryThe flow of blood into the left anterior auricular artery was measured phasically and quantitatively in the heart-lung preparation. The curves indicate that forward flow into the auricular artery occurs during ventricular systole and diastole, with abrupt, momentary interruptions of inflow at the onset of ventricular systole and diastole ...
J R, SMITH, I C, LAYTON
openaire   +2 more sources