Results 11 to 20 of about 1,038,687 (320)

High resolution 3-Dimensional imaging of the human cardiac conduction system from microanatomy to mathematical modeling [PDF]

Scientific Reports, 2017
Cardiac arrhythmias and conduction disturbances are accompanied by structural remodelling of the specialised cardiomyocytes known collectively as the cardiac conduction system.
Robert S. Stephenson, Andrew Atkinson, Petros Kottas, Filip Perde, Fatemeh Jafarzadeh, Mike Bateman, Paul A. Iaizzo, Jichao Zhao, Henggui Zhang, Robert H. Anderson, Jonathan C. Jarvis, Halina Dobrzynski   +11 more
doaj   +3 more sources

Lineages of the Cardiac Conduction System [PDF]

Journal of Cardiovascular Development and Disease, 2017
The cardiac conduction system (CCS) initiates and coordinately propagates the electrical impulse to orchestrate the heartbeat. It consists of a set of interconnected components with shared properties.
Rajiv Mohan, Bas J. Boukens, Vincent M. Christoffels   +2 more
doaj   +3 more sources

Development and Function of the Cardiac Conduction System in Health and Disease [PDF]

Journal of Cardiovascular Development and Disease, 2017
The generation and propagation of the cardiac impulse is the central function of the cardiac conduction system (CCS). Impulse initiation occurs in nodal tissues that have high levels of automaticity, but slow conduction properties.
David S. Park, Glenn I. Fishman
doaj   +3 more sources

Dbh + catecholaminergic cardiomyocytes contribute to the structure and function of the cardiac conduction system in murine heart [PDF]

Nature Communications, 2023
The heterogeneity of functional cardiomyocytes arises during heart development, which is essential to the complex and highly coordinated cardiac physiological function.
Tianyi Sun, Alexander Grassam-Rowe, Zhaoli Pu, Yangpeng Li, Huiying Ren, Yanru An, Xinyu Guo, Wei Hu, Ying Liu, Yuqing Zheng, Zhu Liu, Kun Kou, Xianhong Ou, Tangting Chen, Xuehui Fan, Yangyang Liu, Shu Tu, Yu He, Yue Ren, Ao Chen, Zhouchun Shang, Zhidao Xia, Lucile Miquerol, Nicola Smart, Henggui Zhang, Xiaoqiu Tan, Weinian Shou, Ming Lei   +27 more
doaj   +3 more sources

Genetic and physiologic dissection of the vertebrate cardiac conduction system. [PDF]

PLoS Biology, 2008
Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi, Robin M Shaw, Benno Jungblut, Jan Huisken, Tania Ferrer, Rima Arnaout, Ian Scott, Dimitris Beis, Tong Xiao, Herwig Baier, Lily Y Jan, Martin Tristani-Firouzi, Didier Y R Stainier   +12 more
doaj   +6 more sources

Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells [PDF]

iScience, 2022
Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan, Faheem Ershad, Arfaxad Reyes-Alcaraz, Luge Li, Brandon Mistretta, Lei Gonzalez, Zhoulyu Rao, Cunjiang Yu, Preethi H. Gunaratne, Na Li, Robert J. Schwartz, Bradley K. McConnell   +11 more
doaj   +3 more sources

Spiral-wave Dynamics Depends Sensitively on nhomogeneities in Mathematical Models of Ventricular Tissue [PDF]

Phys. Rev. E 75, 011929 (2007), 2006
Every sixth death in industrialised countries occurs because of cardiac arrhythmias like ventricular tachycardia (VT) and ventricular fibrillation (VF). There is growing consensus that VT is associated with an unbroken spiral wave of electrical activation on cardiac tissue but VF with broken waves, spiral turbulence, spatiotemporal chaos and rapid ...
Pandit, Rahul, Shajahan, T K, Sinha, Sitabhra   +2 more
arxiv   +5 more sources

Complex patterns of spontaneous initiations and terminations of reentrant circulation in a loop of cardiac tissue [PDF]

Journal of Theoretical Biology, 254 (2008) 14-26, 2008
A two-component model is developed that consists of a discrete loop of cardiac cells that circulates action potentials together with a cardiac pacing mechanism. Physiological properties of cells such as restitutions of refractoriness and of conduction velocity are given via experimentally measured functions. The dynamics of circulating pulses and their
Anastasiou-Nana, Banville, Bub, C.K. Cheng, C.M. Baumgarten, Cain, Cain, Cain, Cao, Chay, Chen, Cheng, Cherry, Chialvo, Chow, Courtemanche, Courtemanche, Courtemanche, Cytrynbaum, D.M. Chan, De Bakker, Derksen, Downar, Elaydi, Fox, Fox, Frame, Gilmour, Girouard, Glass, H. Sedaghat, Hall, Harris, Hwang, Ito, J.W. Cain, Jack, Jalife, Kalb, Keener, Kocic, Koller, Koller, Krebs, Kunysz, Lampert, Liebovitch, Lown, M.A. Wood, Manios, Mickens, Mines, Mitchell, Moe, Nagai, Nolasco, Otani, Plonsey, Qu, Quan, Sedaghat, Sedaghat, Stein, Stubna, Ten Tusscher, Vinet, Watanabe, Watanabe, Winkle, Wood, Wood, Wood   +71 more
arxiv   +3 more sources

Death of a 23-year-old man from cardiac conduction system injury through a blunt chest impact after a car accident [PDF]

Egyptian Journal of Forensic Sciences, 2014
Cardiac contusion, usually caused by blunt chest trauma, has been recognized with increased frequency over the past decades. Traffic accidents are the most frequent causes of cardiac contusion resulting from a direct blow to the chest.
S. Zerbo, E. Maresi, F. Portelli, C. Sortino, E. Ventura Spagnolo, P. Procaccianti, A. Argo   +6 more
doaj   +4 more sources

The Intrinsic Cardiac Nervous System and Its Role in Cardiac Pacemaking and Conduction [PDF]

Journal of Cardiovascular Development and Disease, 2020
The cardiac autonomic nervous system (CANS) plays a key role for the regulation of cardiac activity with its dysregulation being involved in various heart diseases, such as cardiac arrhythmias.
Laura Fedele, Thomas Brand
doaj   +2 more sources