Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells
iScience, 2022 Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan +11 more
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Premature MicroRNA-1 Expression Causes Hypoplasia of the Cardiac Ventricular Conduction System. [PDF]
, 2019 Mammalian cardiac Purkinje fibers (PFs) are specified from ventricular trabecular myocardium during mid-gestation and undergo limited proliferation before assuming their final form.
Evangelista, Melissa +5 more
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A 21st century view of the anatomy of the cardiac conduction system
Translational Research in Anatomy, 2022 Introduction: Since the discovery of the major components of the cardiac conduction system (CCS) by the early 20th century we have seen many technological advancements that have allowed immense insight into the CCS tissues. In this review we will discuss
Areej Arshad, Andrew J. Atkinson
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Modeling the Heart as a Communication System [PDF]
, 2014 Electrical communication between cardiomyocytes can be perturbed during arrhythmia, but these perturbations are not captured by conventional electrocardiographic metrics.
Aguilar-Rodríguez, José +7 more
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Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]
, 2016 A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M +4 more
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Development and Function of the Cardiac Conduction System in Health and Disease
Journal of Cardiovascular Development and Disease, 2017 The generation and propagation of the cardiac impulse is the central function of the cardiac conduction system (CCS). Impulse initiation occurs in nodal tissues that have high levels of automaticity, but slow conduction properties.
David S. Park, Glenn I. Fishman
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Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology [PDF]
, 2017 In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed.
Balay S. +17 more
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Genetic and physiologic dissection of the vertebrate cardiac conduction system.
PLoS Biology, 2008 Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi +12 more
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The effects of repetitive electric cardiac stimulation in dogs with normal hearts, complete heart block and experimental cardiac arrest [PDF]
, 1955 Direct cardiac stimulation was conducted in the open chest. In normal animals, auricular stimulation at frequencies faster than the spontaneous rate caused little change in vascular pressures or cardiac output.
GAERTNER, RA, STARZL, TE, WEBB, RC
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Cardiac Conduction System Disorders [PDF]
Cardiac Electrophysiology Clinics, 2021 Thakur R. K., Natale A.
openaire +5 more sources