Acidosis slows electrical conduction through the atrio-ventricular node [PDF]
Acidosis affects the mechanical and electrical activity of mammalian hearts but comparatively little is known about its effects on the function of the atrio-ventricular node (AVN).
Burton, Francis L.+7 more
core +2 more sources
Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology [PDF]
In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed.
Balay S.+17 more
core +3 more sources
Two dimensional electrophysiological characterization of human pluripotent stem cell-derived cardiomyocyte system. [PDF]
Stem cell-derived cardiomyocytes provide a promising tool for human developmental biology, regenerative therapies, disease modeling, and drug discovery.
Gimzewski, James K+7 more
core +2 more sources
Pathology of the Conduction System in Cardiac Rejection [PDF]
Correlation of electrocardiographic abnormalities occurring postoperatively with lesions of the conduction system found at autopsy was done in 20 dogs which had received cardiac homografts. The incidence of arrhythmias closely paralleled the severity of rejection injury found within the heart and specifically within the conduction system.
Charles P. Bieber+2 more
openaire +2 more sources
Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block
Progressive conduction system disease affects patients with transthyretin cardiac amyloidosis, often requiring permanent pacing as the His-Purkinje system is affected. We present a case of left bundle branch pacing in a patient with transthyretin cardiac
Taha Ahmed, MD+5 more
doaj
Unwind to the beat: chromatin and cardiac conduction
How chromatin accessibility and structure endow highly specialized cells with their unique phenotypes is an area of intense investigation. In the mammalian heart, an exclusive subset of cardiac cells comprise the conduction system.
Douglas J. Chapski, Thomas M. Vondriska
doaj +1 more source
His Bundle pacing for congenital complete AV block: An attempt to fix a broken heart?
Congenital complete atrioventricular block (CCAVB) is usually due to failure of atrioventricular nodal conduction with preservation of the HisâPurkinje system.
Giuseppe Pio Piemontese+6 more
doaj +1 more source
All-Optical 4D In Vivo Monitoring And Manipulation Of Zebrafish Cardiac Conduction [PDF]
The cardiac conduction system is vital for the initiation and maintenance of the heartbeat. Over the recent years, the zebrafish (Danio rerio) has emerged as a promising model organism to study this specialized system.
Weber, Michael
core +1 more source
The formation and function of the cardiac conduction system [PDF]
The cardiac conduction system (CCS) consists of distinctive components that initiate and conduct the electrical impulse required for the coordinated contraction of the cardiac chambers. CCS development involves complex regulatory networks that act in stage-, tissue- and dose-dependent manners, and recent findings indicate that the activity of these ...
Jan Hendrik van Weerd+1 more
openaire +3 more sources
Numerical Simulations of Fractionated Electrograms and Pathological Cardiac Action Potential [PDF]
The aim of this work is twofold. First we focus on the complex phenomenon of electrogram fractionation, due to the presence of discontinuities in the conduction properties of the cardiac tissue in a bidomain model.
Simona Sanfelici
core +1 more source