Results 21 to 30 of about 116,699 (313)

The effects and reliability of the hydroxychloroquine-azithromycin combination on the cardiac conduction system in patients with coronavirus disease 2019

open access: diamondJournal of Surgery and Medicine, 2020
Background and Aim: The COVID-19 virus has influenced the whole world since late 2019 and has affected millions of people The combination of hydroxychloroquine (HQ) and azithromycin (AZ) has entered the protocols worldwide to reduce virus replication and take advantage of its immunomodulatory effects The frequency of QTc prolongation in combinational ...
Berat Uğuz   +5 more
openalex   +4 more sources

Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells

open access: yesiScience, 2022
Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan   +11 more
doaj   +1 more source

Engineering a conduction-consistent cardiac patch with rGO/PLCL electrospun nanofibrous membranes and human iPSC-derived cardiomyocytes

open access: yesFrontiers in Bioengineering and Biotechnology, 2023
The healthy human heart has special directional arrangement of cardiomyocytes and a unique electrical conduction system, which is critical for the maintenance of effective contractions.
Yao Tan   +17 more
doaj   +1 more source

Zebrafish Models in Therapeutic Research of Cardiac Conduction Disease

open access: yesFrontiers in Cell and Developmental Biology, 2021
Malfunction in the cardiac conduction system (CCS) due to congenital anomalies or diseases can cause cardiac conduction disease (CCD), which results in disturbances in cardiac rhythm, leading to syncope and even sudden cardiac death.
Rui Gao, Jie Ren
doaj   +1 more source

Desmin variants: Trigger for cardiac arrhythmias?

open access: yesFrontiers in Cell and Developmental Biology, 2022
Desmin (DES) is a classical type III intermediate filament protein encoded by the DES gene. Desmin is abundantly expressed in cardiac, skeletal, and smooth muscle cells.
Wei Su   +5 more
doaj   +1 more source

Familial Dilated Cardiomyopathy and Isolated Left Ventricular Noncompaction Associated With Lamin A/C Gene Mutations [PDF]

open access: yes, 2004
[Abstract] LMNA mutations have been associated with familial or sporadic dilated cardiomyopathy (DC), with or without conduction system disease. We studied the LMNA gene in 67 consecutive patients with DC (18 had familial DC, 17 had possible familial DC,
Bouzas-Zubeldia, Beatriz   +10 more
core   +2 more sources

Bidirectional ventricular tachycardia in cardiac sarcoidosis. [PDF]

open access: yes, 2016
A 73-year-old man with history of pulmonary sarcoidosis was found to have runs of non-sustained bidirectional ventricular tachycardia (BVT) with two different QRS morphologies on a Holter monitor.
Benjamin, Mina M   +4 more
core   +2 more sources

A Case of Complete AV Blockade in Patient with Lyme Borreliosis

open access: yesАрхивъ внутренней медицины, 2022
Lyme disease (tick-borne borreliosis) is an infectious vector-borne natural focal disease that tends to a chronic and recurrent course with a predominant damage to the skin, nervous system, musculoskeletal system and heart. Cardiac features is manifested,
O. N. Denisov   +2 more
doaj   +1 more source

Revolutionizing cardiovascular medicine: targeted therapies for the cardiac conduction system

open access: yesThe Journal of Clinical Investigation, 2022
Arrhythmogenic cardiovascular disorders are associated with considerable morbidity and mortality. Whether cardiac conduction disease is caused by genetic defects, procedural perturbations, valvular disease, ischemia, aging, or heart failure, new ...
Daniel J. Garry   +2 more
doaj   +1 more source

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