First-degree Atrioventricular Block as an Early Marker of Advanced Disease of the Conduction System in a Patient with Hereditary Val142Ile Cardiac Amyloidosis [PDF]
International Journal of Cardiovascular Sciences, 2022 Nágela Simão Vinhosa Nunes +3 more
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Incidence and prognosis of cardiac conduction system diseases in hypertension: the STEP trial
Nature AgingPatients with cardiac conduction system diseases (CSD) may have increased incidence and mortality of cardiovascular events. Here we report a post hoc analysis of the Strategy of Blood Pressure Intervention in the Elderly Hypertensive Patients (STEP) randomized clinical trial (ClinicalTrials.gov number, NCT03015311) concerning the effect of intensive ...
Song Zhao +6 more
openalex +3 more sources
PLoS ONE, 2021 Background Lyme carditis, defined as direct infection of cardiac tissue by Borrelia bacteria, affects up to 10% of patients with Lyme disease. The most frequently reported clinical manifestation of Lyme carditis is cardiac conduction system disease.
Uwajachukwumma A. Uzomah +9 more
doaj +2 more sources
Intensive blood pressure control does not lower risk of cardiac conduction system diseases
Nature AgingSong Zhao, Yi Zhang
openaire +3 more sources
Regulation of Cardiac Conduction and Arrhythmias by Ankyrin/Spectrin-Based Macromolecular Complexes
Journal of Cardiovascular Development and Disease, 2021 The cardiac conduction system is an extended network of excitable tissue tasked with generation and propagation of electrical impulses to signal coordinated contraction of the heart.
Drew Nassal +6 more
doaj +1 more source
Conduction System Diseases—Cardiac Arrhythmias
Jan Steffel, Thomas F. Lüscher
openalex +2 more sources
Genetic and physiologic dissection of the vertebrate cardiac conduction system. [PDF]
PLoS Biology, 2008 Vertebrate hearts depend on highly specialized cardiomyocytes that form the cardiac conduction system (CCS) to coordinate chamber contraction and drive blood efficiently and unidirectionally throughout the organism.
Neil C Chi +12 more
doaj +1 more source
Left Bundle Branch Pacing in Transthyretin Cardiac Amyloidosis and Alternating Bundle Branch Block
JACC: Case Reports, 2020 Progressive conduction system disease affects patients with transthyretin cardiac amyloidosis, often requiring permanent pacing as the His-Purkinje system is affected. We present a case of left bundle branch pacing in a patient with transthyretin cardiac
Taha Ahmed, MD +5 more
doaj +1 more source
Direct reprogramming of cardiomyocytes into cardiac Purkinje-like cells
iScience, 2022 Summary: Currently, there are no treatments that ameliorate cardiac cell death, the underlying basis of cardiovascular disease. An unexplored cell type in cardiac regeneration is cardiac Purkinje cells; specialized cells from the cardiac conduction ...
Nicole Prodan +11 more
doaj +1 more source