Results 101 to 110 of about 4,585,967 (340)

MDCT evaluation of aortic root and aortic valve prior to TAVI. What is the optimal imaging time point in the cardiac cycle?

open access: yesEuropean Radiology, 2015
ObjectivesTo determine the optimal imaging time point for transcatheter aortic valve implantation (TAVI) therapy planning by comprehensive evaluation of the aortic root.MethodsMultidetector-row CT (MDCT) examination with retrospective ECG gating was ...
Tomáš Juřenčák   +9 more
semanticscholar   +1 more source

Downregulation of O‐GlcNAcylation enhances etoposide‐induced p53‐mediated apoptosis in HepG2 human liver cancer cells

open access: yesFEBS Open Bio, EarlyView.
Etoposide, a topoisomerase II inhibitor, reduces O‐GlcNAcylation in HepG2 liver cancer cells. Further inhibition of O‐GlcNAc transferase by OSMI‐1 enhanced etoposide‐induced apoptosis, lowering the IC50 for viability and increasing the EC50 for cytotoxicity.
Jaehoon Lee   +5 more
wiley   +1 more source

When the clock strikes: Modeling the relation between circadian rhythms and cardiac arrhythmias [PDF]

open access: yesarXiv, 2016
It has recently been observed that the occurrence of sudden cardiac death has a close statistical relationship with the time of day, viz., ventricular fibrillation is most likely to occur between 12 am-6 am, with 6 pm-12 am being the next most likely period.
arxiv  

A novel formulation for the study of the ascending aortic fluid dynamics with in vivo data [PDF]

open access: yesarXiv, 2022
Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by applying a rigid wall simplification, on the other side the FSI simulation requires a lot of assumptions for the ...
arxiv  

Identification of murine phosphodiesterase 5A isoforms and their functional characterization in HL-1 cardiac cell line [PDF]

open access: yes, 2017
Phosphodiesterase 5A (PDE5A) specifically degrades the ubiquitous second messenger cGMP and experimental and clinical data highlight its important role in cardiac diseases.
Barbagallo, Federica   +13 more
core   +1 more source

Quantification of myocardial blood flow with cardiovascular magnetic resonance throughout the cardiac cycle

open access: yesJournal of Cardiovascular Magnetic Resonance, 2015
BackgroundMyocardial blood flow (MBF) varies throughout the cardiac cycle in response to phasic changes in myocardial tension. The aim of this study was to determine if quantitative myocardial perfusion imaging with cardiovascular magnetic resonance (CMR)
M. Motwani   +5 more
semanticscholar   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

open access: yesFEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel   +3 more
wiley   +1 more source

Improving visualization of 4D flow cardiovascular magnetic resonance with four-dimensional angiographic data: generation of a 4D phase-contrast magnetic resonance CardioAngiography (4D PC-MRCA)

open access: yesJournal of Cardiovascular Magnetic Resonance, 2017
Magnetic Resonance Angiography (MRA) and Phase-Contrast MRA (PC-MRA) approaches used for assessment of cardiovascular morphology typically result in data containing information from the entire cardiac cycle combined into one 2D or 3D image.
Mariana Bustamante   +3 more
doaj   +1 more source

Assessment Of Response To Heart Failure Therapy: Ventricular Volume Changes Versus Shape Changes [PDF]

open access: yes, 2011
The prolate ellipsoid left ventricular geometry is crucial for its unique contraction and relaxation patterns. Perturbations in optimal cardiac function preceding overt heart failure ensue when this ellipsoid shape assumes a more spherical configuration.
Srilakshmi Adhyapak, V.Rao Parachuri
core   +1 more source

Thoracic aorta cardiac-cycle related dynamic changes assessed with a 256-slice CT scanner [PDF]

open access: yes, 2013
Objective: The aim of our study was to demonstrate whether the dynamic changes previously documented at the ascending and abdominal aorta are replicated at the thoracic aorta.
Capuñay, Carlos   +7 more
core   +1 more source

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