Results 121 to 130 of about 534,991 (349)

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

open access: yesAdvanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi   +1 more
wiley   +1 more source

Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth

open access: yesEpigenetics & Chromatin, 2018
Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes.
Kyohei Oyama   +6 more
doaj   +1 more source

Ischemic Myocardium Targeting Peptide‐Guided Nanobubbles for Multimodal Imaging and Treatment of Coronary Microvascular Dysfunction

open access: yesAdvanced Healthcare Materials, EarlyView.
Nanobubbles functionalized with indocyanine green and ischemic myocardium‐targeting peptide effectively target cardiomyocytes and enable the multimodal (fluorescence, ultrasonic, and photoacoustic) imaging of ischemic myocardium in mice with coronary microvascular dysfunction (CMD).
Bo Yu   +8 more
wiley   +1 more source

L-CO-Net: Learned Condensation-Optimization Network for Clinical Parameter Estimation from Cardiac Cine MRI [PDF]

open access: yesarXiv, 2020
In this work, we implement a fully convolutional segmenter featuring both a learned group structure and a regularized weight-pruner to reduce the high computational cost in volumetric image segmentation. We validated our framework on the ACDC dataset featuring one healthy and four pathology groups imaged throughout the cardiac cycle.
arxiv  

The cycle of form and function in cardiac valvulogenesis

open access: yesAswan Heart Centre Science & Practice Series, 2011
AbstractThe formation and remodeling of the embryonic valves is a complex and dynamic process that occurs within a constantly changing hemodynamic environment. Defects in embryonic and fetal valve remodeling are the leading cause of congenital heart defects, yet very little is known about how fibrous leaflet tissue is created from amorphous gelatinous ...
Stephanie E. Lindsey   +1 more
openaire   +3 more sources

Cardiac cycle oscillatory dynamics in a self-paced precision task [PDF]

open access: yes
Purpose. A gradual and transient lengthening of the cardiac cycle (cardiac deceleration) is typically observed in the few seconds leading to self-paced precision actions and is reported as a feature of expertise.
Gallicchio, Germano   +3 more
core  

TIMING RELATIONSHIPS IN HUMAN CORTICAL PROCESSING [PDF]

open access: yes, 1986
Although a number of studies have suggested that the phases of the alpha cycle and the cardiac cycle reflect temporal relationships in cortical processing, these studies are not conclusive.
RICE, DANIEL MICHAEL
core   +1 more source

Motor‐Free Soft Robots for Cancer Detection, Surgery, and In Situ Bioprinting

open access: yesAdvanced Healthcare Materials, EarlyView.
Novel motor‐free soft robots for cancer detection, surgery, and in situ bioprinting–are presented. This master‐slave system is constructed from soft fibrous syringe architectures, removing the need for electrical motors and complex control mechanisms, while reducing the physical tremors.
Chi Cong Nguyen   +17 more
wiley   +1 more source

Analysis of the basic functions of student’s miocard bioelectric activity during the educational process

open access: yesRUDN Journal of Ecology and Life Safety, 2014
The basic functions of myocard bioelectrical activity in 308 students of 17-20 years of age were studied by means of electrocardiography during the educational process. The research was carried out with medical diagnostic system “Valenta
V N Fedorov
doaj  

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