Results 141 to 150 of about 2,991,997 (281)

Entorhinal Astrocyte Transplants Restore Spatial Exploration and Alleviate Amyloid‐Beta Pathology in Alzheimer's Mice

Advanced Science, EarlyView.
Impaired MEC astrocytic Ca2+ signaling is associated with fragmented spatial exploration in AD mice. Region‐specific glial progenitor transplantation generates engrafted astrocytes that are accompanied by improved AQP4 polarization, reduced amyloid‐β‐associated pathology, attenuated neuroinflammation, preserved synaptic integrity, and ameliorated ...
Fengjuan Wu, Jihua Fan, Xiang Zhou, Zhiqi Yang, Mingyue Gong, Mingzhu Huang, Zhenlu Cai, Shaofan Yang, Teng Teng, Chuanyan Yang, Jin Li, Haoyu Wang, Shuangshuang Dai, Chunhai Chen, Xiaowei Chen, Manxia Wang, Kuan Zhang   +16 more
wiley   +1 more source

Self‐Powered All‐in‐One Wearable Bioelectronics Driven by Pneumatic Energy Buffering of Daily Footsteps

Advanced Science, EarlyView.
A pneumatic energy‐buffering strategy transforms transient and intermittent footsteps into quasi‐continuous electrical energy for a self‐powered wearable biosensing platform. The footwear‐integrated air‐pumping harvester, combined with the rationally designed power‐management system, powers a wearable ankle PPG device with reduced motion artifacts ...
Ji‐Seok Kim, Tae Woog Kang, Hyunjoon Yoo, Jawon Ha, Yunuo Huang, Hee Han, Chi Won Ahn, Woon‐Hong Yeo, Il‐Kwon Oh   +8 more
wiley   +1 more source

Perceived Time Shapes Physical Fatigue Accumulation and Its Neural Oscillatory Correlates

Advanced Science, EarlyView.
Can a clock change the course of physical fatigue? By covertly manipulating the clock calibration during repeated isometric contractions, we showed that perceived time shapes fatigue accumulation and frontal oscillatory dynamics. While fatigue accumulation was only reduced when the clock was slowed down, frontal oscillatory dynamics followed perceived ...
Pierre‐Marie Matta, Julien Duclay, Robin Baurès, Andrea Alamia   +3 more
wiley   +1 more source

Reproducibility of fetal global longitudinal strain measured with speckle tracking echocardiography using a fixed cardiac cycle. [PDF]

PLoS One
Meireson E, de Vet C, van Laar JOEH, Mussche P, Roelens K, van Oostrum NHM.   +5 more
europepmc   +1 more source

Damage‐Free Passivation of Ambipolar OECTs with Fluoropolymer Film for Enhanced Performance and Stability Toward Reliable Biosignal Processing

Advanced Science, EarlyView.
A damage‐free iCVD fluoropolymer passivation strategy is introduced for ambipolar vertical OECTs. Vapor‐phase infiltration and thermal annealing induce nanoscale phase separation in the OMIEC channel, enhancing overall device performance. A single‐channel bipolar event‐driven spiking encoder is also demonstrated for electrocardiogram signal encoding ...
Junyeong Yang, Bohyun Lee, Hanna Lee, Mingyu Kim, Changsoon Choi, Jung Ah Lim, Youson Kim, Sung Gap Im   +7 more
wiley   +1 more source

Prediction of cardiac cycle duration for cardiac-gated closed-loop auricular vagus nerve stimulation. [PDF]

Front Neurosci
Chowdhury D, Schuh K, Kaniusas E.
europepmc   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

Advanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li, Bin Zhang, Zhiqiu Zhang, Bing Zheng, Linhui Han, Chen Yan, Jialin Li, Kaiqiang Sun, Tianyi Zhao, Jiangang Shi   +9 more
wiley   +1 more source

Impact of cardiac cycle and respiratory rhythm phase on visual attention in healthy young and older adults. [PDF]

Sci Rep
Santhana Gopalan PR, Hämäläinen J, Penttonen M, Nokia MS.   +3 more
europepmc   +1 more source

Carrier‐Free Berberine/Nitidine Chloride Self‐Assembled Nanoparticles Induce Ferroptosis to Overcome Bortezomib Resistance in Multiple Myeloma

Advanced Science, EarlyView.
A schematic illustrating the fabrication process and ferroptosis‐mediated therapeutic mechanism of carrier‐free self‐assembled BBR/NC‐SAPs for overcoming bortezomib resistance in multiple myeloma. ABSTRACT Therapeutic relapse driven by bortezomib resistance represents a formidable clinical barrier in the management of multiple myeloma (MM).
Yiwen Lv, Shuang Liu, Hong Wu, Guiluan Li, Ying Rong, Guangchao Li, Yangmin Zhu, Qi Zhong, Ruiming Ou, Huijuan Shen, Zhi Liu, Jing Huang, Zhenwei Wang, Pei Lin, Qing Zhang, Guopan Yu, Zhao Yin   +16 more
wiley   +1 more source

A novel electrocardiogram-synchronized laser Doppler holography system for cardiac cycle-resolved retinal hemodynamics: development and validation. [PDF]

Sci Rep
Wood K, Schnorbus N, Muncharaz L, Lahoti Y, Siesky BA, Guidoboni G, Vercellin AV, Potash S, Greenberg LA, Atlan M, Chui TYP, Rosen R, Harris A.   +12 more
europepmc   +1 more source