Results 141 to 150 of about 4,585,967 (340)
Cell cycle arrest of cardiomyocytes in the context of cardiac regeneration
Frontiers in Cardiovascular MedicineThe limited capacity of adult mammalian cardiomyocytes to undergo cell division and proliferation is one of the key factors contributing to heart failure.
Qingling Xu +8 more
doaj +1 more source
Advanced Functional Materials, EarlyView.The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang +9 more
wiley +1 more source
Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth
Epigenetics & Chromatin, 2018 Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes.
Kyohei Oyama +6 more
doaj +1 more source
The cycle of form and function in cardiac valvulogenesis
Aswan Heart Centre Science & Practice Series, 2011 AbstractThe formation and remodeling of the embryonic valves is a complex and dynamic process that occurs within a constantly changing hemodynamic environment. Defects in embryonic and fetal valve remodeling are the leading cause of congenital heart defects, yet very little is known about how fibrous leaflet tissue is created from amorphous gelatinous ...
Stephanie E. Lindsey +1 more
openaire +3 more sources
Advanced Functional Materials, EarlyView.Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana +2 more
wiley +1 more source
BioMedical Engineering OnLine, 2012 Background Magnetic resonance imaging (MRI) is an important tool for cardiac research, and it is frequently used for resting cardiac assessments. However, research into non-pharmacological stress cardiac evaluation is limited.
Gusso Silmara +6 more
doaj +1 more source
Cardiovascular and respiratory physiopathological aspects of hypokinesia [PDF]
The many effects of hypokinesia on the human organism are described. The differences in normally mobile subjects and hypokinetic subjects as relates to heart rate, average humeral pressure, cardiac capacity, cardia index, systolic range, and large cycle ...
Dagianti, A.
core +1 more source
Journal of Biological Chemistry, 2017 Mavacamten, formerly known as MYK-461 is a recently discovered novel small-molecule modulator of cardiac myosin that targets the underlying sarcomere hypercontractility of hypertrophic cardiomyopathy, one of the most prevalent heritable cardiovascular ...
Raja Kawas +5 more
semanticscholar +1 more source
Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders
Advanced Functional Materials, EarlyView.This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao +5 more
wiley +1 more source