Results 51 to 60 of about 568,260 (340)

Fully automated segmentation and tracking of the intima media thickness in ultrasound video sequences of the common carotid artery [PDF]

open access: yes, 2013
—The robust identification and measurement of the intima media thickness (IMT) has a high clinical relevance because it represents one of the most precise predictors used in the assessment of potential future cardiovascular events.
A. Stanton   +24 more
core   +2 more sources

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

open access: yesFEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani   +7 more
wiley   +1 more source

Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]

open access: yes, 2017
The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel   +21 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

Cardiac alternans and intracellular calcium cycling [PDF]

open access: yesClinical and Experimental Pharmacology and Physiology, 2014
SummaryCardiac alternans refers to a condition in which there is a periodic beat‐to‐beat oscillation in electrical activity and the strength of cardiac muscle contraction at a constant heart rate. Clinically, cardiac alternans occurs in settings that are typical for cardiac arrhythmias and has been causally linked to these conditions.
Joshua N, Edwards, Lothar A, Blatter
openaire   +2 more sources

TIMING RELATIONSHIPS IN HUMAN CORTICAL PROCESSING [PDF]

open access: yes, 1986
Although a number of studies have suggested that the phases of the alpha cycle and the cardiac cycle reflect temporal relationships in cortical processing, these studies are not conclusive.
RICE, DANIEL MICHAEL
core   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Taking Context to Heart: Momentary Emotions, Menstrual Cycle, and Cardiac Autonomic Regulation [PDF]

open access: yes, 2019
Background. Emotions have long been discussed in conjunction with the autonomic nervous system. Most research on heart-mood linkages does not consider sex differences or an evident underlying mechanism for sex differences- sex hormone levels.
Simon, Shauna
core  

Methods and systems for extracting venous pulsation and respiratory information from photoplethysmographs [PDF]

open access: yes, 2019
A system and method for separating a venous component and an arterial component from a red signal and an infrared signal of a PPG sensor is provided.
Nourani, Mehrdad, Yousefi, Rasoul
core   +1 more source

Growth Differentiation Factor 15 Elevation in the Central Nervous System Is Associated With Failure to Thrive in Alexander Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Alexander disease (AxD) is a severe neurodegenerative disorder caused by gain‐of‐function mutations in the gene for GFAP, which lead to protein aggregation and a primary astrocytopathy. Symptoms vary, but failure to thrive (FTT) and frequent emesis are common and cause significant morbidity. Here we investigate GDF15, a member of the
Tracy L. Hagemann   +6 more
wiley   +1 more source

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