The Cardiac Timing Toolbox (CaTT): Testing for physiologically plausible effects of cardiac timing on behaviour [PDF]
There is a long history of, and renewed interest in, cardiac timing effects on behaviour and cognition. Cardiac timing effects may be identified by expressing events as a function of their location in the cardiac cycle, and applying circular (i.e ...
Critchley, HD+3 more
core
Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal
Congenital heart disease (CHD) is the most common birth defect. After birth, patients with CHD may suffer from cardiac stress resulting from abnormal loading conditions.
Marie Günthel+4 more
doaj +1 more source
Machine Learning-based Signal Quality Assessment for Cardiac Volume Monitoring in Electrical Impedance Tomography [PDF]
Owing to recent advances in thoracic electrical impedance tomography, a patient's hemodynamic function can be noninvasively and continuously estimated in real-time by surveilling a cardiac volume signal associated with stroke volume and cardiac output. In clinical applications, however, a cardiac volume signal is often of low quality, mainly because of
arxiv
Cardiac and respiratory motion extraction for MRI using Pilot Tone-a patient study [PDF]
Background: Several studies have shown that both respiratory and cardiac motion can be extracted from the Pilot Tone (PT) signal successfully. However, most of these studies were performed in healthy volunteers. In addition, validating PT using ECG as a reference can be problematic because both PT and ECG tend to be unreliable in patients with ...
arxiv +1 more source
Influence of the cardiac cycle on pCASL: cardiac triggering of the end-of-labeling [PDF]
In arterial spin labeling (ASL), the cardiac cycle might adversely influence signal-stability by varying the amount of label created, labeling efficiency and/or transport times. Due to the long labeling duration in pseudo-Continuous ASL (pCASL), the blood labeled last contributes most to the ASLsignal.
Verbree, J., Osch, M.J.P. van
openaire +4 more sources
Prolonged cardiac NR4A2 activation causes dilated cardiomyopathy in mice [PDF]
Transcription factors play a fundamental role in cardiovascular adaptation to stress. Nuclear receptor subfamily 4 group A member 2 (NR4A2; NURR1) is an immediate-early gene and transcription factor with a versatile role throughout many organs.
Ashraf, Sadia+2 more
core +2 more sources
Indeterminacy of Spatiotemporal Cardiac Alternans [PDF]
Cardiac alternans, a beat-to-beat alternation in action potential duration (at the cellular level) or in ECG morphology (at the whole heart level), is a marker of ventricular fibrillation, a fatal heart rhythm that kills hundreds of thousands of people in the US each year.
arxiv +1 more source
Segmentation of the left ventricle of the heart in 3-D+t MRI data using an optimized nonrigid temporal model [PDF]
Modern medical imaging modalities provide large amounts of information in both the spatial and temporal domains and the incorporation of this information in a coherent algorithmic framework is a significant challenge.
Ghita, Ovidiu+2 more
core +1 more source
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld+7 more
wiley +1 more source
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang+10 more
wiley +1 more source