Results 51 to 60 of about 531,305 (348)

The Cardiac Timing Toolbox (CaTT): Testing for physiologically plausible effects of cardiac timing on behaviour [PDF]

open access: yes, 2022
There is a long history of, and renewed interest in, cardiac timing effects on behaviour and cognition. Cardiac timing effects may be identified by expressing events as a function of their location in the cardiac cycle, and applying circular (i.e ...
Critchley, HD   +3 more
core  

Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal

open access: yesJournal of Cardiovascular Development and Disease, 2021
Congenital heart disease (CHD) is the most common birth defect. After birth, patients with CHD may suffer from cardiac stress resulting from abnormal loading conditions.
Marie Günthel   +4 more
doaj   +1 more source

Machine Learning-based Signal Quality Assessment for Cardiac Volume Monitoring in Electrical Impedance Tomography [PDF]

open access: yesarXiv, 2023
Owing to recent advances in thoracic electrical impedance tomography, a patient's hemodynamic function can be noninvasively and continuously estimated in real-time by surveilling a cardiac volume signal associated with stroke volume and cardiac output. In clinical applications, however, a cardiac volume signal is often of low quality, mainly because of
arxiv  

Cardiac and respiratory motion extraction for MRI using Pilot Tone-a patient study [PDF]

open access: yes, 2022
Background: Several studies have shown that both respiratory and cardiac motion can be extracted from the Pilot Tone (PT) signal successfully. However, most of these studies were performed in healthy volunteers. In addition, validating PT using ECG as a reference can be problematic because both PT and ECG tend to be unreliable in patients with ...
arxiv   +1 more source

Influence of the cardiac cycle on pCASL: cardiac triggering of the end-of-labeling [PDF]

open access: yesMagnetic Resonance Materials in Physics, Biology and Medicine, 2017
In arterial spin labeling (ASL), the cardiac cycle might adversely influence signal-stability by varying the amount of label created, labeling efficiency and/or transport times. Due to the long labeling duration in pseudo-Continuous ASL (pCASL), the blood labeled last contributes most to the ASLsignal.
Verbree, J., Osch, M.J.P. van
openaire   +4 more sources

Prolonged cardiac NR4A2 activation causes dilated cardiomyopathy in mice [PDF]

open access: yes, 2022
Transcription factors play a fundamental role in cardiovascular adaptation to stress. Nuclear receptor subfamily 4 group A member 2 (NR4A2; NURR1) is an immediate-early gene and transcription factor with a versatile role throughout many organs.
Ashraf, Sadia   +2 more
core   +2 more sources

Indeterminacy of Spatiotemporal Cardiac Alternans [PDF]

open access: yes, 2007
Cardiac alternans, a beat-to-beat alternation in action potential duration (at the cellular level) or in ECG morphology (at the whole heart level), is a marker of ventricular fibrillation, a fatal heart rhythm that kills hundreds of thousands of people in the US each year.
arxiv   +1 more source

Segmentation of the left ventricle of the heart in 3-D+t MRI data using an optimized nonrigid temporal model [PDF]

open access: yes, 2008
Modern medical imaging modalities provide large amounts of information in both the spatial and temporal domains and the incorporation of this information in a coherent algorithmic framework is a significant challenge.
Ghita, Ovidiu   +2 more
core   +1 more source

Circulating tumor DNA (ctDNA) trajectories predict survival in trifluridine/tipiracil‐treated metastatic colorectal cancer patients

open access: yesMolecular Oncology, EarlyView.
The authors applied joint/mixed models that predict mortality of trifluridine/tipiracil‐treated metastatic colorectal cancer patients based on circulating tumor DNA (ctDNA) trajectories. Patients at high risk of death could be spared aggressive therapy with the prospect of a higher quality of life in their remaining lifetime, whereas patients with a ...
Matthias Unseld   +7 more
wiley   +1 more source

The accumulation of myeloid‐derived suppressor cells participates in abdominal infection‐induced tumor progression through the PD‐L1/PD‐1 axis

open access: yesMolecular Oncology, EarlyView.
This study explores how sepsis affects GC progression by creating an immunosuppressive environment. Our findings reveal that sepsis promotes immune dysregulation, enhancing tumor growth and metastasis. Targeting the PD‐1/PD‐L1 pathway with monoclonal antibodies shows potential for restoring immune function and improving outcomes in cancer patients ...
Yiding Wang   +10 more
wiley   +1 more source

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