Over expression of Plk1 does not induce cell division in rat cardiac myocytes in vitro. [PDF]
PLoS ONE, 2009 BACKGROUND:Mammalian cardiac myocytes withdraw from the cell cycle during post-natal development, resulting in a non-proliferating, fully differentiated adult phenotype that is unable to repair damage to the myocardium, such as occurs following a ...
Carmen H Coxon +3 more
doaj +1 more source
Regional differences in APD restitution can initiate wavebreak and re-entry in cardiac tissue: A computational study [PDF]
, 2005 Background Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood.
A Garfinkel +37 more
core +3 more sources
Early Postnatal Cardiac Stress Does Not Influence Ventricular Cardiomyocyte Cell-Cycle Withdrawal
Journal of Cardiovascular Development and Disease, 2021 Congenital heart disease (CHD) is the most common birth defect. After birth, patients with CHD may suffer from cardiac stress resulting from abnormal loading conditions.
Marie Günthel +4 more
doaj +1 more source
Interactions between cardiac activity and conscious somatosensory perception
, 2019 Fluctuations in the heart's activity can modulate the access of external stimuli to consciousness. The link between perceptual awareness and cardiac signals has been investigated mainly in the visual and auditory domain. Here, we investigated whether the
Al, E. +5 more
core +1 more source
Accuracy of prediction of infarct-related arrhythmic circuits from image-based models reconstructed from low and high resolution MRI. [PDF]
, 2015 Identification of optimal ablation sites in hearts with infarct-related ventricular tachycardia (VT) remains difficult to achieve with the current catheter-based mapping techniques.
Arevalo, Hermenegild +7 more
core +2 more sources
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]
, 2017 The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel +21 more
core +2 more sources
Cardiac alternans and intracellular calcium cycling [PDF]
Clinical and Experimental Pharmacology and Physiology, 2014 SummaryCardiac alternans refers to a condition in which there is a periodic beat‐to‐beat oscillation in electrical activity and the strength of cardiac muscle contraction at a constant heart rate. Clinically, cardiac alternans occurs in settings that are typical for cardiac arrhythmias and has been causally linked to these conditions.
Joshua N, Edwards, Lothar A, Blatter
openaire +2 more sources
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo +5 more
wiley +1 more source
Reduction of radiation dose for coronary computed tomography angiography using prospective electrocardiography-triggered high-pitch acquisition in clinical routine [PDF]
, 2018 Purpose: To evaluate the image quality, radiation exposure, and means of application in a group of patients who underwent coronary computed tomography angiography (CCTA) performed with low-dose prospective electrocardiography (ECG)-triggered acquisition ...
Chaosuwannakit, Narumol +1 more
core +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Adverse childhood experiences (ACEs) are stressful or traumatic events prior to age 18 that are known to have a lasting impact on individuals’ health and well‐being. There is a gap in understanding the relationship between ACEs and Other Life Stressors and health status for adults with sickle cell disease (SCD).
Marsha Treadwell +8 more
wiley +1 more source