Results 101 to 110 of about 57,859 (256)

Efficacy of Antimicrobial Silver‐Plated Dressings Compared to Usual Care in Preventing Left Ventricular Assist Device Driveline Infections

Artificial Organs, EarlyView.
Integrating silver‐plated wound dressings into DLES care presents a safe and effective strategy for DLI prevention. Key findings include a 100% infection‐free rate in the Silverlon group, no NPWT and hospital readmission in the Silverlon group, and no severe DESTINE stages (3, 4) in the Silverlon group.
Barbara Veiter, Martina Socha, Christiane Marko, Nesibe Seyda Colak, Alexandra Kuhn, Hebe Al Asadi, Julia Riebandt, Roxana Moayedifar, Daniel Zimpfer, Thomas Schlöglhofer   +9 more
wiley   +1 more source

Cardiac Electrophysiology [PDF]

Biophysical Journal, 2008
openaire   +1 more source

Early Multicenter Outcomes of Dedicated Transcatheter Aortic Valve Replacement for Left Ventricular Assist Device‐Associated Pure Aortic Regurgitation

Artificial Organs, EarlyView.
LVAD‐associated aortic regurgitation impairs circulatory support, with limited surgical and off‐label options. In a multicenter registry (n = 30), the AR‐dedicated JenaValve Trilogy TAVR eliminated AR, achieving 96.7% (29/30) technical success and 93.3% (28/30) device success (VARC‐3), with 3.3% (1/30) 30‐day mortality.
Hristian Hinkov, Sara Yousefzada, Isabell A. Just, Christoph Klein, Evgenij Potapov, Santiago Garcia, Dhairya Patel, Lauren S. Ranard, Arseniy Goncharov, Dean J. Kereiakes, Raj R. Makkar, Torsten P. Vahl, Tanja K. Rudolph, Axel Unbehaun   +13 more
wiley   +1 more source

Distinctly altered TRPC3 and TRPC6 expression patterns in human Alzheimer's disease cortex and hippocampus

Brain Pathology, EarlyView.
Divergent remodeling of TRPC channels occurs in Alzheimer's disease, with TRPC3 increased in neurons and reactive astrocytes and TRPC6 reduced in pyramidal neurons. These alterations may contribute to calcium dysregulation, neuroinflammation, and synaptic dysfunction during AD progression.
Xingyong Chen, Zhengjun Wang, Jiaxing Wang, Dehui Kong, Xusheng Wang, Lu Lu, Peter T. Nelson, Fu‐Ming Zhou, Francesca‐Fang Liao   +8 more
wiley   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade, Nathan Morris, Diana E. Sepulveda, Alonso Cortez‐Resendiz, Christopher Brandl, Jennifer E. Lausch, Mariya Starostina, Nicholas M. Graziane   +7 more
wiley   +1 more source

Immune checkpoint inhibitor‐induced arrhythmias: Mechanistic insights from clinical and preclinical studies

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy, but their efficacy continues to be limited by immune‐related adverse events. Among these, ICI‐induced cardiac arrhythmias are increasingly recognised as a major adverse reaction, encompassing a broad spectrum of clinical phenotypes, including conduction blocks, atrial fibrillation and
Anand R. Ramalingam, Zoltán Márton Köhler, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Editorial: New advances in cardiac electrophysiology. [PDF]

Front Cardiovasc Med
Koniari I, Tsiachris D.
europepmc   +1 more source

Cardiac Electrophysiology [PDF]

Critical Care Medicine, 1992
openaire   +1 more source

Arrhythmias associated with immune checkpoint inhibitor therapy—A clinical perspective

British Journal of Pharmacology, EarlyView.
Immune checkpoint inhibitors (ICIs) have transformed cancer therapy but are associated with a growing spectrum of cardiovascular immune‐related adverse events. Among these, arrhythmias represent a rare yet potentially life‐threatening complication. ICI‐induced arrhythmias encompass a wide clinical spectrum, including atrial arrhythmias, conduction ...
Dong Wang, Melanie Ricke‐Hoch, David Duncker, Johann Bauersachs, Dominik Berliner   +4 more
wiley   +1 more source