Results 21 to 30 of about 95,501 (296)

GSDMD-mediated pyroptosis dominantly promotes left ventricular remodeling and dysfunction in post-myocardial infarction: a comparison across modes of programmed cell death and mitochondrial involvement

Journal of Translational Medicine, 2023
Background Myocardial infarction (MI) has recently accounted for more than one-third of global mortality. Multiple molecular pathological pathways, such as oxidative stress, inflammation, and mitochondrial dysfunction, have been recognized as possible ...
Chanon Piamsiri, Chayodom Maneechote, Kewarin Jinawong, Busarin Arunsak, Titikorn Chunchai, Wichwara Nawara, Siriporn C Chattipakorn, Nipon Chattipakorn   +7 more
doaj   +1 more source

Chronic beta-adrenoceptor blockade and human atrial cell electrophysiology: evidence of pharmacological remodelling [PDF]

, 2003
<b>Objective:</b> Chronic beta-adrenoceptor antagonist (β-blocker) treatment reduces the incidence of reversion to AF in patients, possibly via an adaptive myocardial response.
Kane, K.A., Norrie, J., Rankin, A.C., Russell, J.A., Workman, A.J.   +4 more
core   +1 more source

Incorporating Inductances in Tissue-Scale Models of Cardiac Electrophysiology [PDF]

, 2017
In standard models of cardiac electrophysiology, including the bidomain and monodomain models, local perturbations can propagate at infinite speed.
Balay S., Benson A. P., Boyce E. Griffith, Cattaneo C., Colli Franzone P., DeHaan R. L., Fastl T. E., Jou D., Keener J. P., Krueger M. W., MATLAB, Neu J. C., Sachse F. B., Simone Rossi, ten Tusscher K. H. W. J., Thomas C. E., Tung L., Wikswo J. P.   +17 more
core   +3 more sources

Regional differences in APD restitution can initiate wavebreak and re-entry in cardiac tissue: A computational study [PDF]

, 2005
Background Regional differences in action potential duration (APD) restitution in the heart favour arrhythmias, but the mechanism is not well understood.
A Garfinkel, A Karma, A Panfilov, AT Winfree, BH van Huysduynen, C Antzelevitch, CS Kuo, D Noble, DW Frazier, EM Cherry, F Fenton, F Xie, FH Fenton, GK Moe, GX Yan, HN Pak, I Banville, J Han, JM Pastore, K Gima, K Yuuki, KJ Sampson, KJ Sampson, KR Laurita, KR Laurita, MA Watanabe, ML Riccio, MR Franz, P Taggart, P Taggart, PC Viswanathan, Peter Taggart, RH Clayton, RH Clayton, Richard H Clayton, SD Girouard, TJ Hund, ZL Qu   +37 more
core   +3 more sources

Acute dapagliflozin administration exerts cardioprotective effects in rats with cardiac ischemia/reperfusion injury

Cardiovascular Diabetology, 2020
Background A sodium-glucose co-transporter 2 (SGLT-2) inhibitor had favorable impact on the attenuation of hyperglycemia together with the severity of heart failure.
Sarayut Lahnwong, Siripong Palee, Nattayaporn Apaijai, Sirawit Sriwichaiin, Sasiwan Kerdphoo, Thidarat Jaiwongkam, Siriporn C. Chattipakorn, Nipon Chattipakorn   +7 more
doaj   +1 more source

Electrocardiographic and electrophysiological characteristics of idiopathic ventricular arrhythmias with acute successful ablation at the superior portion of the mitral annulus

BMC Cardiovascular Disorders, 2021
Background We sought to identify the electrocardiographic and electrophysiological characteristics of ventricular arrhythmias (VAs), including idiopathic ventricular tachycardia (VT) and premature ventricular contractions (PVCs), with acute successful ...
Chengye Di, Konstantinos P. Letsas, Peng Gao, Qun Wang, Yanxi Wu, Wenhua Lin   +5 more
doaj   +1 more source

Atrial Fibrillation Mechanisms and Implications for Catheter Ablation

Frontiers in Physiology, 2018
AF is a heterogeneous rhythm disorder that is related to a wide spectrum of etiologies and has broad clinical presentations. Mechanisms underlying AF are complex and remain incompletely understood despite extensive research.
Ghassen Cheniti, Ghassen Cheniti, Ghassen Cheniti, Konstantinos Vlachos, Konstantinos Vlachos, Thomas Pambrun, Thomas Pambrun, Darren Hooks, Antonio Frontera, Antonio Frontera, Masateru Takigawa, Masateru Takigawa, Felix Bourier, Felix Bourier, Takeshi Kitamura, Takeshi Kitamura, Anna Lam, Anna Lam, Claire Martin, Claire Martin, Carole Dumas-Pommier, Stephane Puyo, Xavier Pillois, Josselin Duchateau, Josselin Duchateau, Nicolas Klotz, Nicolas Klotz, Arnaud Denis, Arnaud Denis, Nicolas Derval, Nicolas Derval, Pierre Jais, Pierre Jais, Hubert Cochet, Hubert Cochet, Meleze Hocini, Meleze Hocini, Michel Haissaguerre, Michel Haissaguerre, Frederic Sacher, Frederic Sacher   +40 more
doaj   +1 more source

Natural History of Arrhythmia After Successful Isolation of Pulmonary Veins, Left Atrial Posterior Wall, and Superior Vena Cava in Patients With Paroxysmal Atrial Fibrillation: A Multi‐Center Experience

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2021
Background We evaluated long‐term outcome of isolation of pulmonary veins, left atrial posterior wall, and superior vena cava, including time to recurrence and prevalent triggering foci at repeat ablation in patients with paroxysmal atrial fibrillation ...
Sanghamitra Mohanty, Chintan Trivedi, Pamela Horton, Domenico G. Della Rocca, Carola Gianni, Bryan MacDonald, Angel Mayedo, Javier Sanchez, G. Joseph Gallinghouse, Amin Al‐Ahmad, Rodney P. Horton, J. David Burkhardt, Antonio Dello Russo, Michela Casella, Claudio Tondo, Sakis Themistoclakis, Giovanni Forleo, Luigi Di Biase, Andrea Natale   +18 more
doaj   +1 more source

Post-operative atrial fibrillation is influenced by beta-blocker therapy but not by pre-operative atrial cellular electrophysiology [PDF]

, 2006
We investigated whether post-cardiac surgery (CS) new-onset atrial fibrillation (AF) is predicted by pre-CS atrial cellular electrophysiology, and whether the antiarrhythmic effect of beta-blocker therapy may involve pre-CS pharmacological remodeling ...
Kane, Kathleen A., Marshall, Gillian E., Norrie, John, Pau, David, Rankin, Andrew C., Redpath, Calum J., Russell, Julie A., Workman, Antony J.   +7 more
core   +1 more source

Accuracy of prediction of infarct-related arrhythmic circuits from image-based models reconstructed from low and high resolution MRI. [PDF]

, 2015
Identification of optimal ablation sites in hearts with infarct-related ventricular tachycardia (VT) remains difficult to achieve with the current catheter-based mapping techniques.
Arevalo, Hermenegild, Ashikaga, Hiroshi, Deng, Dongdong, Halperin, Henry, McVeigh, Elliot, Pashakhanloo, Farhad, Prakosa, Adityo, Trayanova, Natalia   +7 more
core   +5 more sources