Results 211 to 220 of about 145,404 (307)

Circular PVT1 promotes cardiac fibroblast activation interacting with miR-30a-5p and miR-125b-5p. [PDF]

Cell Death Dis
Bibi A, Madè A, Greco S, Garcia-Manteiga JM, Tascini AS, Tastsoglou S, Zaccagnini G, Leszek P, Gaetano C, Martelli F.   +9 more
europepmc   +1 more source

Equine models in translational medicine: A comparative approach to human health

Animal Models and Experimental Medicine, EarlyView.
This diagram summarizes and contrasts rodent and equine models, outlining their strengths, limitations, and applications. Horses offer naturally occurring diseases, genetic and physiological similarities to humans, and suitability for longitudinal and clinical‐scale studies.
Shayan Boozarjomehri Amnieh, Katarzyna Ropka‐Molik   +1 more
wiley   +1 more source

Persistent Fibrosis in Heart Failure With a Reduced Ejection Fraction Linked to Phenotypic Differences in Human Cardiac Fibroblast Populations. [PDF]

J Am Heart Assoc
Biggs RM, Zhang Y, Silverman DN, Baicu CF, Van Laer AO, Wakefield L, Bhatt D, Masline S, Neff LS, Kilic A, Witer LJ, Houston BA, Coeyman SJ, Richardson WJ, Zile MR, Bradshaw AD.   +15 more
europepmc   +1 more source

The characteristics of collagen‐induced rheumatoid arthritis in macaques and the changes of heart

Animal Models and Experimental Medicine, EarlyView.
The disease progression in CIA macaques was categorized into three stages: IIR (days 14–34): The indicators related to rheumatoid arthritis and the levels of immunoglobulin were all elevated. There was a small amount of joint effusion, edema and mild synovial hyperplasia. No joint swelling was observed by naked eye.
Lei Zhang, Haifeng Jiang, Zhen Xu, Tingyu Dong, Xiaoyi Liu, Shangxue Yan, Jiajie Kuai, Yan Chang, Wei Wei   +8 more
wiley   +1 more source

ERK3 is involved in regulating cardiac fibroblast function. [PDF]

Physiol Rep
Sahadevan P, Dingar D, Nawaito SA, Nair RS, Trépanier J, Sahmi F, Shi Y, Gillis MA, Sirois MG, Meloche S, Tardif JC, Allen BG.   +11 more
europepmc   +1 more source

Morphological and morphometric aspects of the equine aortic valve: New insights for comparative studies in mammals

The Anatomical Record, EarlyView.
Abstract New data on the equine aortic valve obtained using advanced techniques is especially important given the greater availability of animal models for translational research. Here we characterized the morphological and morphometric aspects of the equine aortic valve from 60 healthy hearts collected at equine abattoirs.
Vitor Pires Pereira, Victoria Brondani de Oliveira, Carlos Eduardo Seyfert, Luciano de Morais‐Pinto   +3 more
wiley   +1 more source

Expression of concern: "Ferroptosis in diabetic cardiomyopathy: Advances in cardiac fibroblast-cardiomyocyte interactions" [Heliyon 10 (2024) e35219]. [PDF]

Heliyon
europepmc   +1 more source

In Vitro Assessment of Cardiac Fibroblast Activation at Physiologic Stiffness. [PDF]

Curr Protoc
Goldsmith RS, Tsan YC, Scissors RE, Helms AS, Brody MJ.   +4 more
europepmc   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Cardiac fibroblast-mediated ECM remodeling regulates maturation in an in vitro 3D engineered cardiac tissue. [PDF]

J Tissue Eng
Jang Y, Kang M, Kang YG, Lee D, Jung HG, Yoon DS, Kim J, Park Y.   +7 more
europepmc   +1 more source