Results 151 to 160 of about 1,567,002 (208)
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Biochemical Pharmacology, 2019
The cardiac glycoside oleandrin is a main active constituent of the botanical anti-cancer drug candidate PBI-05204, an extract of Nerium oleander. Here, we aimed to determine the circadian sensitivity of mice to oleandrin, and to investigate the role of ...
C. Zhou +6 more
semanticscholar +1 more source
The cardiac glycoside oleandrin is a main active constituent of the botanical anti-cancer drug candidate PBI-05204, an extract of Nerium oleander. Here, we aimed to determine the circadian sensitivity of mice to oleandrin, and to investigate the role of ...
C. Zhou +6 more
semanticscholar +1 more source
Cardiac glycosides. 7. Sugar stereochemistry and cardiac glycoside activity
Journal of Medicinal Chemistry, 1986Digitoxigenin alpha-L-, beta-L-, alpha-D-, and beta-D-glucosides; alpha-L-, beta-L-, alpha-D-, and beta-D-mannosides; and alpha-L- and beta-L-rhamnosides were stereoselectively synthesized from the corresponding sugar tetrabenzyl trichloroacetimidates.
H, Rathore +3 more
openaire +2 more sources
Naturally occurring cardiac glycosides
Medical Journal of Australia, 1986Cardiac glycoside poisoning from the ingestion of plants, particularly of oleanders, occurs with reasonable frequency in tropical and subtropical areas. We have assessed a variety of plant specimens for their cardiac glycoside content by means of radioimmunoassays with antibodies that differ in their specificity for cardiac glycosides.
Radford, DJ +3 more
openaire +4 more sources
Clinical toxicology, 2018
Background: Consumption of yellow oleander (Cascabela thevetia) is a popular method of intentional self-harm in South India. Objectives: The objectives of this study were to identify the cardiac arrhythmias and electrolyte abnormalities in yellow ...
A. D. +4 more
semanticscholar +1 more source
Background: Consumption of yellow oleander (Cascabela thevetia) is a popular method of intentional self-harm in South India. Objectives: The objectives of this study were to identify the cardiac arrhythmias and electrolyte abnormalities in yellow ...
A. D. +4 more
semanticscholar +1 more source
1994
Publisher Summary This chapter discusses endogenous cardiac glycosides. The cardiac glycosides comprise a class of organic compounds derived largely from plant sources that have been used for millennia as therapeutic agents. Other clinically relevant cardiac glycosides are derived from the leaves of Digitalis lanata from which digitoxin and digoxin
R A, Kelly, T W, Smith
openaire +2 more sources
Publisher Summary This chapter discusses endogenous cardiac glycosides. The cardiac glycosides comprise a class of organic compounds derived largely from plant sources that have been used for millennia as therapeutic agents. Other clinically relevant cardiac glycosides are derived from the leaves of Digitalis lanata from which digitoxin and digoxin
R A, Kelly, T W, Smith
openaire +2 more sources
Cytoskeleton, 2018
Recently drug‐induced senescence has gained momentum as a new approach in cancer therapy. It is accepted that senescent cells display typical phenotypic features including flattened, enlarged, and multinucleated cell morphology.
Y. Şimay +3 more
semanticscholar +1 more source
Recently drug‐induced senescence has gained momentum as a new approach in cancer therapy. It is accepted that senescent cells display typical phenotypic features including flattened, enlarged, and multinucleated cell morphology.
Y. Şimay +3 more
semanticscholar +1 more source