Results 241 to 250 of about 280,420 (306)

Second‐generation prokineticin PKR1 receptor agonists: Advancing cardioprotection against chemotherapy‐induced toxicity

open access: yesBritish Journal of Pharmacology, EarlyView.
IS39, a novel non‐peptide PKR1 agonist, confers cardioprotection against doxorubicin‐induced toxicity. IS39 activates PKR1‐mediated pro‐survival signalling in cardiomyocytes, reducing reactive oxygen species (ROS), DNA damage and fibrosis markers. In vivo, IS39 preserves cardiac geometry and function in mice exposed to chronic doxorubicin challenge ...
Anais Audebrand   +8 more
wiley   +1 more source

A circular RNA derived from the ryanodine receptor 2 locus controls cardiac hypertrophy and calcium handling. [PDF]

open access: yesCell Mol Life Sci
Pan W   +17 more
europepmc   +1 more source

Activation of FoxO1 prevents and reverses cardiac hypertrophy from diverse stimuli. [PDF]

open access: yesJ Mol Cell Cardiol
Martin TG   +4 more
europepmc   +1 more source
Some of the next articles are maybe not open access.

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Experimental Cardiac Hypertrophy

New England Journal of Medicine, 1970
STUDIES on the process by which enlargement of the heart occurs1 2 3 4 have been aided by developments in molecular biology.
openaire   +2 more sources

Endothelin and Cardiac Hypertrophy

Life Sciences, 1997
Cardiac hypertrophy is a commonly observed complication of a variety of cardiovascular diseases. As well as mechanical stresses such as pressure overload, several humoral factors may contribute to the development of cardiac hypertrophy. In the early 1990s, endothelin-1 (ET-1) was found to induce cardiomyocyte hypertrophy in cultured neonatal rat ...
openaire   +2 more sources

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