Results 251 to 260 of about 280,420 (306)

Mechanisms of Cardiac Hypertrophy

Heart Failure Clinics, 2005
Cardiac hypertrophy is a response of myocardium to various physiologic and pathologic stimuli, mechanical and hormonal, that causes the heart to work harder under conditions of increased workload [1–3]. Different cardiovascular diseases, such as aortic stenosis, hypertension, and myocardial infarct, cause mechanical stretching on cardiac walls. Cardiac
SELVETELLA, GIULIO, LEMBO, Giuseppe
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Lipofuscin in Cardiac Hypertrophy

Beiträge zur Pathologie, 1972
Summary Quantitative investigations on the lipofuscin content in human hearts from various weight classes should allow us to conclude whether or not a correlation exists between pigment content and the degree of cardiac hypertrophy. The investigations were performed on 7 μ thick tissue sections from 12 autopsied hearts, and included microscopic ...
W, Sandritter, B, Bierfreund, F, Pannen, C P, Adler   +3 more
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Cardiac hypertrophy and hypertension

Current Opinion in Nephrology and Hypertension, 1998
In the general population and in patients with essential hypertension the presence of left ventricular hypertrophy is a powerful predictor of cardiovascular events, independent of blood pressure and other cardiovascular risk factors. The prevalence of left ventricular hypertrophy increases with age and with the severity of renal impairment.
AGABITI ROSEI, Enrico, MUIESAN, Maria Lorenza   +1 more
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Cardiac Hypertrophy in Hypertension

New England Journal of Medicine, 1987
Over the past three decades, increasing attention has focused on the hypertensive diseases. During this period, antihypertensive therapy was introduced, and its safety and efficacy were demonstrate...
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H19 in cardiac hypertrophy

Nature Reviews Cardiology, 2020
Gene therapy with H19, a highly conserved long non-coding RNA H19, prevents and reverses pathological cardiac hypertrophy in animal models, according to a study by Thomas Thum and colleagues.
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Growth Factor for Cardiac Hypertrophy

Molecular and Cellular Biochemistry, 1993
Cardiac size can be regulated by the balance in activity between cardiac growth factors and inhibiting factors, chalones. This study was undertaken to verify the role of the cardiac growth factor and its purification from hypertrophied hearts. For this propose the hypertrophied hearts of renovascular hypertensive rats were used.
M, Nagano, T, Ohkubo, T, Arino, M, Tsuchiya, M, Nagai   +4 more
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Mitochondrial Proliferation in Cardiac Hypertrophy

Basic Research in Cardiology, 1980
Mitochondrial proliferation was studied in mature female rats following aortic constriction. Mitochondrial DNA (mtDNA) was assayed by a fluorometric method. The conditions for removal of nuclear DNA were developed and verified by assessment of molecular conformation of DNA.
R, Zak, M, Rabinowitz, C, Rajamanickam, S, Merten, B, Kwiatkowska-Patzer   +4 more
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Mitochondria and Cardiac Hypertrophy

2017
Cardiac tissue responds to long-term hemodynamic load through initiation of a hypertrophic remodeling program. Importantly, if not counteracted this response will eventually lead to organ failure. Cardiac hypertrophic adaptations are complex, and involve multiple cellular events and the mechanisms underlying the development of cardiac hypertrophy are ...
Heberty di Tarso Fernandes, Facundo, Robert Eli, Brainard, Francisco Rodrigo de Lemos, Caldas, Aline Maria Brito, Lucas   +3 more
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Catecholamines in cardiac hypertrophy

The American Journal of Cardiology, 1999
There has been intense interest in the roles catecholamines may play in compensatory myocardial hypertrophy. This article reviews the following: (1) chronic infusions of catecholamines in experimental animals result in cardiac hypertrophy, but in many of the studies mechanical factors have played a role; (2) experiments using isolated papillary muscles
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Cardiac dilatation and hypertrophy

American Heart Journal, 1957
Abstract Experimental and clinical evidence contrary to the theory of injury of the heart accompanying dilatation as a cause of cardiac hypertrophy is cited. Results from repetition and extension of the basic experiments from which the theory was launched fail to support the theory.
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