Results 41 to 50 of about 177,041 (162)

Table4_Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis.XLSX

open access: yes, 2022
Cardiac hypertrophy initially serves as an adaptive response to physiological and pathological stimuli. Sustained hypertrophy progress to pathological cardiac hypertrophy, cardiac fibrosis and ultimately lead to heart failure, one of the leading medical ...
Yan Chen (4308)   +8 more
core   +1 more source

Mechanisms for the transition from physiological to pathological cardiac hypertrophy

open access: yes, 2019
The heart is capable of responding to stressful situations by increasing muscle mass, which is broadly defined as cardiac hypertrophy. This phenomenon minimizes ventricular wall stress for the heart undergoing a greater than normal workload.
Oldfield, Christopher J.   +2 more
core   +2 more sources

Image2_Identification of circular RNAs in cardiac hypertrophy and cardiac fibrosis.TIF

open access: yes, 2022
Cardiac hypertrophy initially serves as an adaptive response to physiological and pathological stimuli. Sustained hypertrophy progress to pathological cardiac hypertrophy, cardiac fibrosis and ultimately lead to heart failure, one of the leading medical ...
Yan Chen (4308)   +8 more
core   +1 more source

Cardiac hypertrophy in human stem cells-derived cardiomyocytes : Biomarker identification and pathway analysis of endotheline-1 induced cardiac hypertrophy in human induced pluripotent stem cells-derived cardiomyocytes

open access: yes, 2020
Cardiac hypertrophy is when heart muscles thicken as an adaptive response to several stimuli. Prolonged pathological cardiac hypertrophy can lead to heart failure and severe cardiovascular diseases.
Tangruksa, Benyapa
core  

TNIP3 protects against pathological cardiac hypertrophy by stabilizing STAT1

open access: yes
Pathological cardiac hypertrophy is one of the major risk factors of heart failure and other cardiovascular diseases. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown.
Xiao-Jing Zhang   +14 more
core   +1 more source

Modeling Human Cardiac Hypertrophy in Stem Cell-Derived Cardiomyocytes [PDF]

open access: yes, 2018
Cardiac hypertrophy accompanies many forms of cardiovascular diseases. The mechanisms behind the development and regulation of cardiac hypertrophy in the human setting are poorly understood, which can be partially attributed to the lack of a human ...
Nils Bomer   +18 more
core   +1 more source

LncRNA Sirt1-AS Protects Against Cardiac Hypertrophy by Modulating Sirt1

open access: yes
Background LncRNAs are pivotal regulators in cardiovascular diseases. Sirt1-AS, a lncRNA, has been shown to play a role in cardiovascular diseases. This study aimed to explore the role of Sirt1-AS in cardiac hypertrophy and the underlying molecular ...
Yongqin He   +5 more
core   +1 more source

Investigating the Mechanism of Hyperglycemia-Induced Fetal Cardiac Hypertrophy.

open access: yes, 2015
Hyperglycemia in diabetic mothers enhances the risk of fetal cardiac hypertrophy during gestation. However, the mechanism of high-glucose-induced cardiac hypertrophy is not largely understood.
Xiao-yu Wang   +23 more
core   +1 more source

Nuclear receptor corepressor 1 represses cardiac hypertrophy

open access: yes, 2019
The function of nuclear receptor corepressor 1 (NCoR1) in cardiomyocytes is unclear, and its physiological and pathological implications are unknown. Here, we found that cardiomyocyte-specific NCoR1 knockout (CMNKO) mice manifested cardiac hypertrophy at
Shi, Xue-Rui   +49 more
core   +1 more source

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