Results 111 to 120 of about 1,015,327 (288)

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu   +12 more
wiley   +1 more source

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Multi‐Tissue Crosstalk Regulating Meniscus Healing Under Inflammation and Physiological Loading

open access: yesAdvanced Science, EarlyView.
Using a novel Meniscus‐on‐a‐chip (MoC) model integrated with a meniscus‐specific bioreactor, this study investigated the roles of multi‐tissue crosstalk that regulates injury, healing, and degeneration of the meniscus injury under inflammation and pathophysiological loading.
Hun Jin Jeong   +5 more
wiley   +1 more source

Using of discriminant analysis for diagnostics chronic cardiac insufficiency on teenagers

open access: yes, 2010
В статье авторами предлагается диагностическая модель начальных стадий хронической сердечной недостаточности, полученная в результате дискриминантного анализа клинических, инструментальных и лабораторных показателей.
Антоненко, В. Г.   +6 more
core  

[Dihydromyricetin improves cardiac insufficiency by inhibiting HMGB1 in diabetic rats]. [PDF]

open access: yesNan Fang Yi Ke Da Xue Xue Bao, 2022
Liu S, Liu Q, Peng Q, Zhang Y, Wang J.
europepmc   +1 more source

Smart Bioinks for 4D Bioprinting: Requirements, Design, and Applications

open access: yesAdvanced Science, EarlyView.
Smart bioinks empower 4D‐bioprinted constructs to dynamically adapt and remodel in response to stimuli, effectively biomimicking native tissues. Artificial Intelligence (AI) and Machine Learning (ML) play a guiding role in their rational design by optimizing relevant properties.
Shangsi Chen   +11 more
wiley   +1 more source

IF SYNUS RHYTHM RESTORATION IMPACTS EFFICIENCY OF CARDIAC RESYNCHRONIZATION THERAPY IN PATIENTS WITH SEVERE CARDIAC INSUFFICIENCY AND CONSTANT ATRIAL FIBBRILATION [PDF]

open access: yes, 2019
We analyzed influence of sinus rhythm restoration in patients with severe heart insufficiency and permanent atrial fibrillation on efficiency of cardiac resynchronization therapy.
M. V. Zlobina   +4 more
core  

Can Tricuspid Annuloplasty of the Donor Heart Reduce Valve Insufficiency following Cardiac Transplantation with Bicaval Anastomosis?

open access: yes, 2010
Background: The aim of this study was to evaluate the degree of tricuspid valve insufficiency after orthotopic cardiac transplantation with bicaval anastomosis and prophylactic donor heart annuloplasty.
DIAS, Ricardo R.   +21 more
core   +1 more source

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