Results 131 to 140 of about 184,376 (296)

Multiscale Architecture and Mechanics of the Cell Nucleus: Implications for Disease, Bioengineering and Nanomedicine

Advanced Science, EarlyView.
Nuclear mechanical properties are inherently scale‐dependent, arising from a hierarchical architecture that spans DNA, chromatin, the nuclear envelope, and condensates. Experimental techniques and theoretical models are integrated into a cohesive multiscale framework linking nanoscale structural features to organelle‐level mechanical behavior.
Xinran Liu, Xin Chen, Qingyang Zhao, Weikang Tan, Lingrui Zhu, Kin Liao, Vincent Chan, Nicolae Goga, Winfred O. Larkotey, Yang Li, Yinghui Shi, Wenya Shu, Lin Wang, Weiqing Wang, Tian Jian Lu, Yulong Han   +15 more
wiley   +1 more source

Light‐Switched Mesenchymal Stem Cells for In Situ Exosome Amplification in Craniofacial Bone Defect Reconstruction

Advanced Science, EarlyView.
Light‐switchable MSCs (MSC‐UCNPs) were constructed by intracellular incorporation of UCNPs. Upon 980 nm irradiation, UCNPs emitted localized ultraviolet light (365 nm), activating the ROS/HEXB/LAMP1 signaling pathway to suppress lysosome–multivesicular body fusion and thereby enhance exosome biogenesis. Embedded within an injectable hydrogel, MSC‐UCNPs
Tingting Wu, Yajing Liu, Shuman Wang, Xiaoming Bai, Luyun Zhang, Yuwei Liu, Zhiwen Fu, Chen Shi   +7 more
wiley   +1 more source

The influence of pulmonary insufficiency on ventricular function following total correction of Fallot's tetralogy: evaluation using radionuclide ventriculography and clinical findings

The Turkish Journal of Pediatrics, 1993
Long-standing pulmonary insufficiency after repair of tetralogy of Fallot may adversely affect ventricular function. We evaluated 20 patients postoperatively by radionuclide ventriculography and clinical findings after total correction of ...
S Arsan, C Yorgancioğlu, I Paşaoğlu, B Erbaş, A Y Bozer   +4 more
doaj  

Cardiac Tamponade as the Initial Presentation of Coexistent Systemic Lupus Erythematosus and Addison’s Disease: A Case Report and Literature Review

Journal of Investigative Medicine High Impact Case Reports
Cardiac tamponade is a rare presentation of systemic lupus erythematosus (SLE), occurring in less than 1% of cases. Its coexistence with primary adrenal insufficiency (Addison’s disease) represents an even rarer clinical scenario.
Abdullah Abu Keshek MD, Mohammad Hakam Shehadeh MD, Mohammed M. Salahaldin MD, Salem K. Qupp MD, Omar Mohammad Marouf MD, Ahmad A. Dallashi MD   +5 more
doaj   +1 more source

IF SYNUS RHYTHM RESTORATION IMPACTS EFFICIENCY OF CARDIAC RESYNCHRONIZATION THERAPY IN PATIENTS WITH SEVERE CARDIAC INSUFFICIENCY AND CONSTANT ATRIAL FIBBRILATION

, 2019
We analyzed influence of sinus rhythm restoration in patients with severe heart insufficiency and permanent atrial fibrillation on efficiency of cardiac resynchronization therapy.
M. V. Zlobina, S. N. Krivolapov, S. V. Popov, R. E. Batalov, D. I. Lebedev   +4 more
core  

Cardiac myxoma with mitral valve insufficiency: report of three cases [PDF]

, 2013
Kardiak miksomalar, kalbin en sık görülen primer tümörleridir. Genellikle sol atriumda bulunduklarından, çoğu kez mitral kapağa doğru prolabe olurlar ve çıkarıldıktan sonra bazen rezidüel miral kapak yetmezliğine neden olabilirler.
Darçın, Osman Tansel, Bakalım, Tamer, Ercişli, Murat, Baçgel, Feray Funda, İlbey, Abdullatif   +4 more
core  

Takotsubo Cardiomyopathy Following Cardiac Surgery

, 2015
BackgroundTakotsubo cardiomyopathy syndrome, commonly occurring in postmenopausal women, is characterized by transient apical systolic dysfunction in absence of coronary lesions. The cardiomyopathy is often observed after intense stressful events such as
Crea, Filippo, Chiariello, Giovanni Alfonso, Massetti, Massimo, Piergiorgio Bruno, Filippo Crea, Christian Colizzi, Massimo Massetti, Bruno, Piergiorgio, Colizzi, Christian, Giovanni Alfonso Chiariello   +9 more
core   +1 more source

CK2α Deficiency Drives Myocardial Fibrosis via Desmin‐Induced Mitochondrial Dysfunction

Advanced Science, EarlyView.
CK2α preserves mitochondrial homeostasis by phosphorylating Desmin to recruit Cryab, ensuring proper filament assembly. CK2α deficiency disrupts this interaction, causing mitochondrial dysfunction, metabolic shifts, bioenergetic failure, and oxidative stress—ultimately establishing a pro‐fibrotic environment that drives cardiac fibrosis.
Canjie Ma, Jiali Jia, Juncong Lan, Jing Wang, Dan Rao, Lanlan Rao, Weibin Zhang, Dongpeng Wu, Jie Zhang, Gang Wang, Baohua Liu, Ying Ao, Zimei Wang   +12 more
wiley   +1 more source

Evaluation and treatment of secondary tricuspid insufficiency

, 1992
To define the role of functional tricuspid insufficiency and right ventricular (RV) failure in patients with mitral disease, the data of 121 patients with secondary tricuspid insufficiency that underwent mitral valve replacement (MVR) from January 1982 ...
C. Russo, M. Lanfranchi, A. Pellegrini, E. Quaini, T. Colombo, E. Vitali, F. Donatelli   +6 more
core   +1 more source

Integrated Ultrasonic Platform for Bioelectronic Control through Biological Barriers Based on Metasurface

Advanced Science, EarlyView.
A metasurface‐enabled ultrasonic platform achieves precise multi‐focal control through biological barriers, real‐time physiology‐driven modulation, and simultaneous wireless power and data transmission. By unifying wavefront engineering, closed‐loop feedback, and acoustic communication, this work establishes key enabling technologies toward scalable ...
Chuanxin Zhang, Hanjie Xiao, Xue Jiang, Dean Ta   +3 more
wiley   +1 more source