Results 121 to 130 of about 93,083 (312)
Journal of Applied Toxicology, EarlyView.ABSTRACT One of the most serious complications associated with the use of the chemotherapeutic agent doxorubicin (DOX) is cardiomyopathy. Although cardioprotective drugs such as angiotensin receptor‐neprilysin inhibitors (ARNI) are used to prevent cardiomyopathy in DOX patients, no studies have reported the relationship between ARNI and endoplasmic ...
Mert Unvan +3 more
wiley +1 more source
The impairment of ILK related angiogenesis involved in cardiac maladaptation after infarction.
PLoS ONE, 2011 BackgroundIntegrin linked kinase (ILK), as an important component of mechanical stretch sensor, can initiate cellular signaling response in the heart when cardiac preload increases.
Jun Xie +6 more
doaj +1 more source
Cardiac Myocytes and Mechanosensation
, 2012 Mechanosensation is a fundamental process in biology and may have been developed by the early cells in response to hypo-osmotic stress [1]. With the evolution of different cell types and the appearance of multi-cellular organisms the mechanisms of mechanosensation and the corresponding transmission of signals became more complex and evolved in ...
Byambajav Buyandelger, Ralph Knll
openaire +2 more sources
Journal of Clinical Laboratory Analysis, EarlyView.A 53 year‐old male with type 2 diabetes presented extremely elevated BNP (> 4000 pg/mL) but normal NT‐proBNP and cardiac function. Systematic verification confirmed severe heterophilic antibody (HAMA) interference in the BNP chemiluminescence immunoassay.
Huicong Yang +6 more
wiley +1 more source
, 2005 Background - Although pharmacological block of the slow, delayed rectifier potassium current (I-Ks) by chromanol 293B, L-735,821, or HMR-1556 produces little effect on action potential duration (APD) in isolated rabbit and dog ventricular myocytes, the ...
Lengyel, Csaba Attila +10 more
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Pufferfish exposure and presumed tetrodotoxicosis in Australian dogs: 372 cases (2007–2018)
Australian Veterinary Journal, EarlyView.Introduction Tetrodotoxin (TTX) is a neurotoxin found in pufferfish that results in the blockade of excitatory conduction and clinical signs including gastrointestinal upset and paralysis. The objectives of this study were to describe the epidemiology of pufferfish exposure and presumed tetrodotoxicosis in dogs, and to determine associations with the ...
J Hanson, CR Sharp, EM Leister
wiley +1 more source
British Journal of Haematology, EarlyView.This study shows that sickle cell disease patients have elevated high‐sensitivity cardiac troponin I (hs‐cTnI) that is not considered clinically significant but are outside of the normal range. Elevated hs‐cTnI was associated with low haemoglobin and a history of heart failure.
Abdelrhman Mohammed +3 more
wiley +1 more source
Non‐canonical PKG1 regulation in cardiovascular health and disease
British Journal of Pharmacology, EarlyView.It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley +1 more source
Scientific ReportsHumoral factors regulating cardiac myocytes have not yet been fully elucidated. Using mass spectrometry, we analyzed peptides released from primary neonatal rat cardiac fibroblasts to identify a 24-amino-acid peptide with an intramolecular disulfide bond.
Tsukasa Osaki +11 more
doaj +1 more source
In vitro epigenetic reprogramming of human cardiac mesenchymal stromal cells into functionally competent cardiovascular precursors [PDF]
, 2012 Adult human cardiac mesenchymal-like stromal cells (CStC) represent a relatively accessible cell type useful for therapy. In this light, their conversion into cardiovascular precursors represents a potential successful strategy for cardiac repair.
Andrea Barbuti (106295) +59 more
core +1 more source