Results 151 to 160 of about 81,793 (267)

Wnt5a-YAP signaling axis mediates mechanotransduction in cardiac myocytes and contributes to contractile dysfunction induced by pressure overload. [PDF]

iScience, 2023
Kishimoto H, Iwasaki M, Wada K, Horitani K, Tsukamoto O, Kamikubo K, Nomura S, Matsumoto S, Harada T, Motooka D, Okuzaki D, Takashima S, Komuro I, Kikuchi A, Shiojima I.   +14 more
europepmc   +1 more source

Repolarization adaptation to rapid change in heart rate in human models – a review

The Journal of Physiology, EarlyView.
Abstract figure legend This review focuses on non‐invasive assessment of repolarization duration and dispersion (heterogeneity) adaptation to change in heart rate (HR). HR was increased incrementally by left atrial pacing during an electrophysiology (EP) study and by a bolus injection of atropine and in a step up/down fashion by repeated right atrial ...
Lennart Bergfeldt, Karl‐Jonas Axelsson, Pia Dahlberg, Farzad Vahedi, Gunilla Lundahl, Lennart Gransberg   +5 more
wiley   +1 more source

[Expression of Concern] Novel insights into the role of HSP90 in cytoprotection of H2S against chemical hypoxia‑induced injury in H9c2  cardiac myocytes. [PDF]

Int J Mol Med
Yang Z, Yang C, Xiao L, Liao X, Lan A, Wang X, Guo R, Chen P, Hu C, Feng J.   +9 more
europepmc   +1 more source

Expression of Concern: Insulin Protects Cardiac Myocytes from Doxorubicin Toxicity by Sp1-Mediated Transactivation of Survivin. [PDF]

PLoS One, 2023
PLOS ONE Editors.
europepmc   +1 more source

Development of a protein synthesis network at the sarco/endoplasmic reticulum in adult cardiac myocytes

The Journal of Physiology, EarlyView.
Abstract figure legend Spatial integration of the sarcoplasmic reticulum and protein synthesis machinery in mature cardiac muscle: a schematic of the sarco/endoplasmic reticulum network in a cardiac myocyte, depicting the integrated relationships between the perinuclear endoplasmic reticulum (ER) (A), the sarcoplasmic reticulum (SR) (B), and the ...
Christoph Sandmann, Sören Brandenburg, Dennis Uhlenkamp, Bianca Meyer, Clara Sandmann, Nicole Herzog, Julia Groß, Charlotta Funaya, Hugo A. Katus, Stephan E. Lehnart, Christopher C. Glembotski, Mirko Völkers, Shirin Doroudgar   +12 more
wiley   +1 more source

ATIP1 Is a Suppressor of Cardiac Hypertrophy and Modulates AT2-Dependent Signaling in Cardiac Myocytes. [PDF]

Cells
Fischer T, Gredy S, Scheel N, Benz PM, Fissler B, Ullrich M, Abeßer M, Rokita AG, Reichle J, Maier LS, Ritter O, Baba HA, Schuh K.   +12 more
europepmc   +1 more source

Independent regulation of Z-lines and M-lines during sarcomere assembly in cardiac myocytes revealed by the automatic image analysis software sarcApp. [PDF]

Elife, 2023
Neininger-Castro AC, Hayes JB, Sanchez ZC, Taneja N, Fenix AM, Moparthi S, Vassilopoulos S, Burnette DT.   +7 more
europepmc   +1 more source

Deciphering pro‐arrhythmogenic mechanisms of EPAC in human atrial cardiomyocytes

The Journal of Physiology, EarlyView.
Abstract figure legend This study aimed to investigate the effect of exchange proteins directly activated by cAMP (EPAC) on the regulation of human atrial cardiomyocyte electrophysiology and their potential involvement in the onset of atrial fibrillation (AF).
Arthur Boileve, Margaux Aize, Maximin Détrait, Laura Brard, Adrien Leboyer, Pierre‐Antoine Dupont, Alexandre Lebrun, Vladimir Saplacan, Christophe Simard, Fabien Brette, Frank Lezoualc'h, Laurent Sallé   +11 more
wiley   +1 more source

Ca²⁺ microdomain-based excitation-transcription coupling in cardiac myocytes and vascular smooth muscle cells. [PDF]

Inflamm Regen
Koide T, Giles WR, Kondo R, Imaizumi Y, Yamamura H, Suzuki Y.   +5 more
europepmc   +1 more source

Computational modelling of cardiac fibroblast signalling reveals a key role for Ca2+ in driving atrial fibrillation‐associated fibrosis

The Journal of Physiology, EarlyView.
Abstract figure legend A pre‐existing fibroblast signalling model was enhanced by integrating atrial‐specific components and reactions linked to atrial fibrosis and atrial fibrillation (AF). The analysis highlights the central role of Ca2⁺ signalling in driving profibrotic responses to AF‐relevant stimuli, angiotensin‐II and transforming growth factor ...
Najme Khorasani, Haibo Ni, Jeffrey J Saucerman, Dobromir Dobrev, Stefano Morotti, Eleonora Grandi   +5 more
wiley   +1 more source