Results 161 to 170 of about 81,793 (267)

Distinct intracellular spatiotemporal expression of Calmodulin genes underlies functional diversity of Calmodulin-dependent signalling in cardiac myocytes. [PDF]

Cardiovasc Res
Bogdanov V, Mariangelo JIE, Soltisz AM, Sakuta G, Pokrass A, Beard C, Orengo BH, Kalinin R, Ulker A, Yunker B, Tikunova S, Thuma J, Xu X, Hund TJ, Veeraraghavan R, Davis JP, Györke S.   +16 more
europepmc   +1 more source

Transcriptional Effects of Candidate COVID-19 Treatments on Cardiac Myocytes. [PDF]

Front Cardiovasc Med, 2022
Jakobi T, Groß J, Cyganek L, Doroudgar S.   +3 more
europepmc   +1 more source

Amyloid β alters vascular CaV1.2 channel spatiotemporal properties

The Journal of Physiology, EarlyView.
Abstract figure legend Amyloid‐β1‐42 (Aβ1‐42) triggers a male‐specific signalling cascade influencing CaV1.2 spatiotemporal properties in cerebral vascular smooth muscle. The signalling pathway involves NADPH oxidase (NOX)‐derived reactive oxygen species (ROS) activation of protein kinase C (PKC). Aβ1‐42 can also activate protein kinase A (PKA).
Jade L. Taylor, Miguel Martin‐Aragon Baudel, Eric Pereira da Silva, Johannes W. Hell, Madeline Nieves‐Cintron, Manuel F. Navedo   +5 more
wiley   +1 more source

Nanoscale architecture and dynamics of Ca_V1.3 channel clusters in cardiac myocytes revealed by single channel nanoscopy. [PDF]

J Mol Cell Cardiol Plus
Schwenzer N, Tsukanov R, Kohl T, Basak S, Sobitov I, Seibertz F, Kapoor R, Voigt N, Enderlein J, Lehnart SE.   +9 more
europepmc   +1 more source

Healthy cardiac myocytes can decrease sympathetic hyperexcitability in the early stages of hypertension. [PDF]

Front Synaptic Neurosci, 2022
Davis H, Liu K, Li N, Li D, Paterson DJ.
europepmc   +1 more source

The role of extracellular vesicles in cell–cell crosstalk in cardiotoxicity

The Journal of Physiology, EarlyView.
Abstract figure legend Administration of a pharmacological agent can result in off‐target cardiotoxicity which can be driven by cell–cell crosstalk between healthy and dysfunctional cardiac cells. Extracellular vesicles (EVs) are lipid bilayer structures that can move biological cargo between cells, facilitating cell–cell crosstalk.
Gabriella Bachynskyj‐Bilas, Debbie J. Otto, Daniel Stratton, Katja Rietdorf, Daniel M. Johnson, Calum J. McMullen   +5 more
wiley   +1 more source

Myosin binding protein-C modulates loaded sarcomere shortening in rodent permeabilized cardiac myocytes. [PDF]

J Gen Physiol
McDonald KS, Kalogeris TJ, Veteto AB, Davis DJ, Hanft LM.   +4 more
europepmc   +1 more source

A stochastic mathematical model for coupling the cytosolic and sarcoplasmic calcium movements in diseased cardiac myocytes. [PDF]

Eur Biophys J, 2022
Arif S.
europepmc   +1 more source

Energetic microdomains and the vascular control of neuronal and muscle excitability: Toward a unified model

The Journal of Physiology, EarlyView.
Abstract figure legend The capillary–mitochondria–ion channel (CMIC) axis scales structural resources to match functional workload. (Left) In settings of restricted energetic capacity (e.g. cortical neurons), sparse capillary networks and modest mitochondrial pools set a lower energetic ceiling, sufficient to support phasic, low‐workload excitability. (
L. Fernando Santana, Scott Earley
wiley   +1 more source

Pharmacological Inhibition of β Myosin II Disrupts Sarcomere Assembly in Human iPSC-Derived Cardiac Myocytes. [PDF]

Cytoskeleton (Hoboken)
Hayes JB, Burnette DT.
europepmc   +1 more source