Results 71 to 80 of about 1,441,839 (397)

The impairment of ILK related angiogenesis involved in cardiac maladaptation after infarction. [PDF]

open access: yesPLoS ONE, 2011
BackgroundIntegrin linked kinase (ILK), as an important component of mechanical stretch sensor, can initiate cellular signaling response in the heart when cardiac preload increases.
Jun Xie   +6 more
doaj   +1 more source

The role of Volatile Anesthetics in Cardioprotection: a systematic review. [PDF]

open access: yes, 2012
This review evaluates the mechanism of volatile anesthetics as cardioprotective agents in both clinical and laboratory research and furthermore assesses possible cardiac side effects upon usage.
Applegate, Richard L   +5 more
core   +1 more source

The Space Within: How Architected Voids Promote Tissue Formation

open access: yesAdvanced Materials, EarlyView.
This review explores the role of void spaces in tissue engineering scaffolds and examines four key methods for introducing porosity into hydrogels at different scales. It discusses sacrificial templating, microgels, phase separation, and 3D printing, highlighting principles, advantages, and limitations. It also addresses emerging strategies integrating
Anna Puiggalí‐Jou   +3 more
wiley   +1 more source

Incorporated fish oil fatty acids prevent action potential shortening induced by circulating fish oil fatty acids

open access: yesFrontiers in Physiology, 2010
Increased consumption of fatty fish, rich in omega-3 polyunsaturated fatty acids (3-PUFAs) reduces the severity and number of arrhythmias. Long term 3-PUFA-intake modulates the activity of several cardiac ion channels leading to cardiac action ...
Hester M Den Ruijter   +2 more
doaj   +1 more source

From Millimeters to Micrometers; Re-introducing Myocytes in Models of Cardiac Electrophysiology

open access: yesFrontiers in Physiology, 2021
Computational modeling has contributed significantly to present understanding of cardiac electrophysiology including cardiac conduction, excitation-contraction coupling, and the effects and side-effects of drugs.
Karoline Horgmo Jæger   +4 more
doaj   +1 more source

Biochemical and immunochemical analysis of the arrangement of connexin43 in rat heart gap junction membranes [PDF]

open access: yes, 1990
A 43 × 10^3 M_r protein (designated connexin43 or Cx43) is a major constituent of heart gap junctions. The understanding of its arrangement in junctional membranes has been extended by means of site-directed antibodies raised against synthetic peptides ...
Laird, D. W., Revel, J.-P.
core  

Atrial fibrillation and electrophysiology in transgenic mice with cardiac-restricted overexpression of FKBP12 [PDF]

open access: yes, 2019
Cardiomyocyte-restricted overexpression of FK506-binding protein 12 transgenic (αMyHC-FKBP12) mice develop spontaneous atrial fibrillation (AF). The aim of the present study is to explore the mechanisms underlying the occurrence of AF in αMyHC-FKBP12 ...
Ai, Tomohiko   +14 more
core   +1 more source

Fueling cardiac myocyte proliferation

open access: yesThe Journal of Cardiovascular Aging
[Image: see text]
Manisha Deogharia, Priyatansh Gurha
openaire   +2 more sources

Intracellular Na+ regulation in cardiac myocytes [PDF]

open access: yesCardiovascular Research, 2003
Intracellular [Na+] ([Na+]i) is regulated in cardiac myocytes by a balance of Na+ influx and efflux mechanisms. In the normal cell there is a large steady state electrochemical gradient favoring Na+ influx. This potential energy is used by numerous transport mechanisms, including Na+ channels and transporters which couple Na+ influx to either co- or ...
Donald M, Bers   +2 more
openaire   +2 more sources

Construction of a Multitissue Cell Atlas Reveals Cell‐Type‐Specific Regulation of Molecular and Complex Phenotypes in Pigs

open access: yesAdvanced Science, EarlyView.
This research conducts an in‐depth investigation of cell‐type‐specific regulatory mechanisms underlying molecular and complex phenotypes through integrative analysis of multitissue single‐nucleus RNA sequencing, bulk RNA‐seq, and genome‐wide association study (GWAS) data in pigs.
Lijuan Chen   +31 more
wiley   +1 more source

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