Results 201 to 210 of about 1,444,670 (278)

Mitochondrial Fusion and Fission in Age‐Related Cardio‐Cerebral Diseases: Mechanisms and Interventions

Aging Cell, Volume 25, Issue 10, October 2026.
Mitochondrial fission‐fusion imbalance contributes to age‐related cardio‐cerebral diseases like Alzheimer's disease, Parkinson's disease, Cerebral Infarction, Arteriosclerosis, Myocardial Infarction, Cardiac valve disease, Hypertension, and Cardiomyopathy. This review summarizes its regulatory mechanisms and interventions.
Yuyao Yin, Zijian Li
wiley   +1 more source

The Impact of Aging on the Tongue Proteome. [PDF]

Muscles
Ohlendieck K, Zweyer M, Nebeling F, Swandulla D, Dowling P.   +4 more
europepmc   +1 more source

Repeated Moderate and Severe Heat Exposure Has Divergent Effects on Skeletal Muscle Mitochondrial, Proteostatic and Neuromuscular Outcomes in Mice

Acta Physiologica, Volume 242, Issue 10, October 2026.
ABSTRACT Aim Repeated heat exposure may promote adaptive remodeling or cumulative tissue burden depending on thermal dose, but its graded molecular and functional consequences during recovery remain unclear. We examined whether repeated moderate (39°C) and severe (41°C) whole‐body hyperthermia produce distinct skeletal muscle trajectories involving ...
Cansu Yakin, Cihan Suleyman Erdogan, Fatma Ozge Tuncel, Yunus Kosif, Bayram Yilmaz   +4 more
wiley   +1 more source

Hypertrophic cardiomyopathy: state of the art on diagnosis and current therapeutic approach. [PDF]

Cardiovasc Ultrasound
La Franca E, Parisi F, Lucchino A, Sade LE, Wong T, Loddo I, Alioto L, Gentile G, Pilato M, Cipriani M, Faletra FF.   +10 more
europepmc   +1 more source

Proteomic profiling identifies candidate biomarkers for small intestinal neuroendocrine tumours G1 and G2

Journal of Neuroendocrinology, Volume 38, Issue 10, October 2026.
Abstract Although small intestinal neuroendocrine tumours (SI‐NET) Grade 1 (G1) and 2 (G2) are often studied together, clinical course and response to treatment may differ. We hypothesized that these tumour groups express different markers in blood that may inform future treatment strategies. Blood from 107 SI‐NET patients (G1 n = 64, G2 n = 43) and 50
Malin Grönberg, Dimitrios Papantoniou, Eva Tiensuu Janson   +2 more
wiley   +1 more source

Mechanisms and biomarkers of immune checkpoint inhibitor-associated myocarditis: from T cell imbalance to multicellular crosstalk. [PDF]

Front Immunol
Huang J, Xu X, Jin Y, Qiao L, Yu H, Gao W, Li C.   +6 more
europepmc   +1 more source

Multi‐omics identifies promoter methylation and gene expression changes associated with human skeletal muscle atrophy

Experimental Physiology, Volume 111, Issue 10, Page 4763-4780, 1 October 2026.
Abstract Skeletal muscle atrophy is a secondary complication in the aetiology of injury and chronic disease. Identifying mechanisms that control muscle mass is necessary to characterise atrophy and develop prevention strategies. We aimed to integrate transcriptomic and epigenomic data to identify key regulatory pathways controlled by promoter DNA ...
Jamie‐Lee M. Thompson, Thomas M. Doering, Boris P. Budiono, Kristen L. Mackenzie‐Shalders, Kevin J. Ashton, Paul J. Dunn, Vernon G. Coffey   +6 more
wiley   +1 more source

B-Cell Immune Responses in Myocarditis: Mechanisms, B-Cell Receptor Repertoire, and Clinical Translation. [PDF]

Cells
Lin X, Yao X, Li J.
europepmc   +1 more source

Determining properties of human‐induced pluripotent stem cell‐derived cardiomyocytes using spatially resolved electromechanical metrics

The Journal of Physiology, Volume 604, Issue 19, Page 8069-8099, 1 October 2026.
Abstract figure legend In this study, we use human‐induced pluripotent stem cell‐derived cardiomyocyte (hiPSC‐CM) experiments and computational modelling to identify the mechanism of action of drug compounds. In the hiPSC‐CM experiments, optical measurements of cell collections are recorded in the baseline case and after drug exposure.
Karoline Horgmo Jæger, Verena Charwat, Kevin E. Healy, Samuel Wall, Aslak Tveito   +4 more
wiley   +1 more source

Multi-omics insight into cardiac myofibril remodeling in post-prandial Burmese pythons. [PDF]

Commun Biol
Martin TG, Suarez-Artiles L, Woulfe KC, Melhedegaard EG, Tan Y, Hunt DR, Kirkpatrick BE, Nguyen L, Lee J, Laskey I, Anseth KS, Ochala J, Gotthardt M, Mertins P, Leinwand LA.   +14 more
europepmc   +1 more source