Results 121 to 130 of about 40,259 (213)

SORBS2: A Molecular Nexus in Multisystem Diseases Through Scaffold‐Mediated Regulation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Sorbin and SH3 Domain Containing 2 (SORBS2), a multifunctional scaffold protein harbouring Sorbin homology (SoHo) and Src homology 3 (SH3) domains, serves as a molecular hub in human diseases by integrating cytoskeletal remodelling, signal transduction and RNA metabolic regulation. This study systematically analyses SORBS2's molecular features,
Qiwei Jia, Yong Zhang
wiley   +1 more source

Bed rest decreases resting skeletal muscle O2 uptake and resting energy expenditure in young and elderly subjects

open access: yesExperimental Physiology, Volume 111, Issue 5, Page 2599-2612, 1 May 2026.
Abstract A decrease in resting muscle O2 uptake (V̇O2m${\dot V_{{{\mathrm{O}}_2}{\mathrm{m}}}}$) described during bed rest (BR) could determine a decreased whole‐body resting energy expenditure (REE), potentially useful during prolonged spaceflights. Two groups of recreationally active men (young [Y], n = 8, age 23 ± 5 years; elderly [E], n = 10, age ...
Giovanni Baldassarre   +14 more
wiley   +1 more source

Cardiac myosin inhibitors in hypertrophic cardiomyopathy: advancing care with caution. [PDF]

open access: yesAnn Med Surg (Lond)
Rehman Z   +4 more
europepmc   +1 more source

Ether-a-go-go related gene-1a potassium channel abundance varies within specific skeletal muscle fiber type [PDF]

open access: yes, 2019
Anderson, Luke B.   +5 more
core   +1 more source

Cardiac myosin inhibitors - a cutting-edge solution for the management of hypertrophic cardiomyopathy: a narrative review. [PDF]

open access: yesAnn Med Surg (Lond)
Younas A   +13 more
europepmc   +1 more source

Cardiac myosin inhibitors for hypertrophic cardiomyopathy: a systematic review and meta-analysis of randomized controlled trials. [PDF]

open access: yesAnn Med Surg (Lond)
Hasana U   +14 more
europepmc   +1 more source

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