Results 141 to 150 of about 20,886 (213)

Serum Response Factor Cooperates With Progesterone Receptor to Regulate Oviductal Smooth Muscle Gene Expression During Preimplantation Embryo Transport

The FASEB Journal, Volume 40, Issue 20, 31 October 2026.
Oviductal smooth muscle contractions are important for preimplantation embryo transport under the regulation of steroid hormone signaling. Deletion of serum response factor (Srf) in progesterone receptor (Pgr)‐expressing cells leads to differential expression of 1670 genes in the mouse oviduct, 306 of which are directly bound by SRF.
Peter F. Lais, Ryan M. Marquardt, San‐Pin Wu, John P. Lydon, Francesco J. DeMayo   +4 more
wiley   +1 more source

Complication management in hypertrophic cardiomyopathy. [PDF]

Heart Fail Rev
Höller V, Zwetsloot PP, Santner V, Schwegel N, Pötsch SL, Verheyen N, Michels M.   +6 more
europepmc   +1 more source

Mechanistic diversity within RLC-dependent myosin ATPase inhibitors differentiates EDG-7500, a diastolic-selective cardiac sarcomere modulator. [PDF]

JCI Insight
Emter CA, Henze M, DuVall M, Lehman S, Lee L, Barthel B, Hawryluk NA, Madden M, Wu Y, Perry A, Beyer M, Wei E, Rupert C, Roof S, Peter A, DiNatale E, Cantrell S, Tolley J, Schlachter S, van der Velden J, Michels M, Seidman C, Ma W, Leinwand L, Campbell S, Ochala J, Bluemke D, Tharp D, Seidman J, Del Rio CL, Semigran M, Evanchik M, Koch K, Russell A.   +33 more
europepmc   +1 more source

Structure-Function Relationship as the Foundation for Cardiac Myosin Inhibition in Hypertrophic Cardiomyopathy. [PDF]

Circulation
Kawana M, Ruppel KM, Spudich JA.
europepmc   +1 more source

Decompensated heart failure after one year of successful therapy with mavacamten: a case report. [PDF]

Eur Heart J Case Rep
Marchionni G, Netti L, Stavagna S, Chimenti C.   +3 more
europepmc   +1 more source

Knowledge mapping of targeted therapy for hypertrophic cardiomyopathy: A bibliometric analysis of myosin inhibitor research. [PDF]

Medicine (Baltimore)
Liu N, Yang L, Tian W, Song X, Fu H, Zhang H, Wang J, Zhu Z, Qu Z, Shang Q.   +9 more
europepmc   +1 more source

Hypertrophic Cardiomyopathy is a Disease of Sarcomere Proteins. [PDF]

Methodist Debakey Cardiovasc J
Marian AJ.
europepmc   +1 more source

Impaired Cardiac Myosin Super-Relaxation as an Energy-Dissipating Process in Human Heart Failure with Reduced Ejection Fraction. [PDF]

JACC Basic Transl Sci
Ma W, Chaami C, Melhedegaard EG, Lewis CTA, Zhang C, Guo M, Flannagan H, Landim-Vieira M, Pyle WG, Campbell KS, Ochala J.   +10 more
europepmc   +1 more source

Targeting cardiac myosin in HFrEF: mechanism, clinical evidence, and the role of omecamtiv mecarbil. [PDF]

J Cardiothorac Surg
Abady E, Elewa M, Karam KN, Mathew KT, Bedair M, Almashaqbeh SN, Alwarraqi AG, AbuEl-Enien H, Samadi Y, Abouelmad K.   +9 more
europepmc   +1 more source

Hypertrophic Cardiomyopathy in the Era of Precision Medicine: Redefining Diagnosis, Therapeutics and Risk. [PDF]

Card Fail Rev
Saldarriaga C.
europepmc   +1 more source