Results 161 to 170 of about 19,651 (218)

The Dawn of a New Era in Hypertrophic Cardiomyopathy. [PDF]

Acta Cardiol Sin
Yu WC.
europepmc   +1 more source

6‐Shogaol Attenuates Doxorubicin‐Induced Cardiac and Skeletal Muscle Atrophy by Inhibiting E3 Ubiquitin Ligases and Necroptosis

Phytotherapy Research, Volume 40, Issue 6, Page 3132-3149, June 2026.
Doxorubicin induces cardiac and skeletal muscle atrophy by upregulating E3 ubiquitin ligases, inhibiting myogenic regulatory factors, and activating necroptosis. Cardiac atrophy can further exacerbate cardiotoxicity. 6‐Shogaol negatively regulates these processes and attenuates doxorubicin‐induced cardiac and skeletal muscle atrophy.
Xipeng Sun, Yaxian Wang, Quanjun Yang, Bo Xin, Jinlu Huang, Cheng Guo   +5 more
wiley   +1 more source

Evolving strategies in obstructive hypertrophic cardiomyopathy: myosin inhibitors as monotherapy compared with beta-blockers. [PDF]

Heart Fail Rev
Grupper A, Sverdlov AL, Cheema BS, Nasrollahizadeh A, Hosseini K.   +4 more
europepmc   +1 more source

Integrative Advances in Equine Genomics From Reference Assemblies to Evolutionary History and Key Traits

Evolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Horses are major domestic animals and cultural symbols that have accompanied humans for millennia. They underpin transport, agriculture, warfare and sport, and also provide a model for studying domestication, complex traits and adaptive evolution.
Ying Lu, Ruoshan Ma, Bo Wang, Jiao Wu, Yuqing Chong, Zhendong Gao, Weidong Deng   +6 more
wiley   +1 more source

Mavacamten in Obstructive Hypertrophic Cardiomyopathy and C282Y Homozygous Hereditary Hemochromatosis: A First-in-Human Report. [PDF]

JACC Case Rep
Sam R, Ananthaneni A, Planek MI, Kogan A, Gordon R.   +4 more
europepmc   +1 more source

ATRIAL AND VENTRICULAR ARRHYTHMIAS IN PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY TREATED WITH CARDIAC MYOSIN INHIBITORS: A SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS

L. Sánchez, Paweł Łajczak, Mrinal Murali Krishna, Meghna Joseph, Mable Pereira, Caterina Lecchi, Wajid Majeed DANISH Mir, Chidubem Ezenna, José Ramón Ruíz Arroyo   +8 more
openalex   +1 more source

Cardiac Myosin Inhibitors and Risk of Atrial Fibrillation in Hypertrophic Cardiomyopathy: A Meta-Analysis of Randomised Controlled Trials [PDF]

Thalys Sampaio Rodrigues, M. Shawki, C. Brick, A. Koshy, Johan H. Gibcus, A. Teh, H. Lim, Louise M. Burrell, J. Theuerle   +8 more
openalex   +1 more source

Maternal cardiometabolic dysfunction and fetal sex‐specific alterations to uterine vascular reactivity in an ovine model of obesity during pregnancy

The Journal of Physiology, Volume 604, Issue 12, Page 5011-5030, 15 June 2026.
Abstract figure legend We developed a novel ovine model of diet‐induced maternal obesity, where ewes were fed a control or obesogenic diet for 60 days pre‐pregnancy and throughout gestation. Pregnant ewes were surgically instrumented to assess maternal cardiovascular function near term.
Rachael C. Crew, Anna L. K. Cochrane, Youguo Niu, Sage G. Ford, Clement L. R. Cahen, Skaai H. Davison, Michael P. Murphy, Susan E. Ozanne, Dino A. Giussani   +8 more
wiley   +1 more source

Pharmacologic therapies for hypertrophic cardiomyopathy: The past, the present, and the future. [PDF]

JRSM Cardiovasc Dis
Halațiu VB, Cozac DA, Scridon A.
europepmc   +1 more source

Brave new drugs, enduring old skills: why surgery still matters in the cardiac myosin inhibitor era [PDF]

Hisham Ahamed, Praveen Kerala Varma
openalex   +1 more source