Results 221 to 230 of about 6,808 (263)
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Cardiac myosin Phylogenic and pathological changes
1977Several proteins of the sarcomere differ from one muscle to the other, but it is also becoming evident that cardiac myosin, tropomyosin and troponin are species specific. Moreover, several properties of cardiac myosin could be modified under the influence of thyroxine, exercise, or overloading.
B, Swynghedauw, K, Schwartz, J J, Léger
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Ca-independent regulation of cardiac myosin
1987Calcium-independent regulation of the contractile proteins of cardiac muscle has been studied using hyperpermeable cells from rat ventricles and sections of quickly frozen rat hearts. These preparations have been used to study maximum Ca-activated force, myosin ATPase activity and the maximum velocity of unloaded shortening.
S, Winegrad +5 more
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Cardiac and skeletal muscle myosin polymorphism
Medicine & Science in Sports & Exercise, 1986Skeletal muscles, unlike cardiac tissue, express several myosin isozymes during development which differ in primary structure from adult myosin. Monoclonal antibodies have shown the presence of at least two embryonic myosins, followed by a post-hatch myosin that persists until the appearance of adult myosin in chicken pectoralis muscle.
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Internal flexibility of cardiac myosins
Journal of Thermal Analysis, 1996Conventional and saturation transfer electron paramagnetic resonance spectroscopy (EPR and ST EPR) and differential scanning calorimetry (DSC) were used to study the motional dynamics and segmental flexibility of cardiac myosins. Cardiac myosins isolated from bovine and human heart muscle were spin-labelled with isothiocyanate- or maleimide-based probe
D. LŐrinczy, J. Belágyi
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T Cells in Cardiac Myosin-Induced Myocarditis
Clinical Immunology and Immunopathology, 1993Autoimmune myocarditis induced by immunization with cardiac myosin can be seen as a virus-free system to analyze the immunopathological mechanisms of certain forms of postinfectious heart disease. Immunodepletion studies have shown that in A.SW mice myosin-induced myocarditis is mediated by both CD4+ and CD8+ cells. The CD4+ subset is at least required
N, Neu +3 more
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Monoclonal Antibodies Against Cardiac Myosin Heavy Chain
Hybridoma, 1990Three mouse IgG1 monoclonal antibodies (MAbs), named FA1, FA2, and FA3, against cardiac myosin heavy chain (MHC) with high specificity have been obtained. The immunogen used to generate these MAbs was the high-salt- and detergent-insoluble fraction of adult rat myocardial tissue.
J P, Jin, M L, Malik, J J, Lin
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Dissociation of Light Chains from Cardiac Myosin
European Journal of Biochemistry, 1978The substrate, ATP, protects the active site of cardiac myosin during a 10‐min treatment at 37°C and neutral pH in the absence of divalent cations; under these conditions there is an approximate 20% dissociation of light chain C1 and 60% loss of light chain C2 with no corresponding decrease in myosin ATPase activity. Higher temperatures, the absence of
M, Higuchi +4 more
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Cardiac Myosin in Heart Overloading
1981The heart, like most types of tissues, can adapt to envirommental factors and, more specifically, to its load. Overloading a heart as well as changing its initial length may increase work by means of two successive adaptational processes: (1) immediately by bringing the muscle’s own mechanical properties into play and (2) at a later stage by changing ...
B. Swynghedauw +5 more
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Hormonal influences on cardiac myosin ATPase activity and myosin isoenzyme distribution
Molecular and Cellular Endocrinology, 1984It has been recognized for a long time that changes in hormone secretion can influence cardiac function; however, the biochemical basis for these changes has only recently been clarified. In this review the influences of hormonal status on the contractile protein myosin is discussed. Myosin has a rod-like portion and a globular head and consists of two
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Segmental flexibility of cardiac myosins.
Acta physiologica Hungarica, 1997Conventional and saturation transfer electron paramagnetic resonance spectroscopy (EPR and ST EPR) and differential scanning calorimetry (DSC) were used to study the motional dynamics and structural stability of cardiac myosins. Cardiac myosins isolated from bovine and human heart muscle were spin-labelled with a maleimide- or an iodoacetamide-based ...
J, Belágyi, U, Hoffmann, D, Lörinczy
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