Dominant myosin storage myopathy mutations disrupt striated muscles in Drosophila and the myosin tail-tail interactome of human cardiac thick filaments. [PDF]
Viswanathan MC +7 more
europepmc +1 more source
Recent Polygenic Adaptation in Heavily Fished Malawi Cichlids
ABSTRACT Intense fishing pressure can drive rapid evolution in wild populations, yet the underlying genomic mechanisms often remain elusive. Here, we investigate the genomic consequences of five decades of intense harvesting on the cichlid fish Copadichromis mloto in Lake Malombe, Malawi.
Alexander Hooft van Huysduynen +5 more
wiley +1 more source
A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motif. [PDF]
Goluguri RR +8 more
europepmc +1 more source
Abstract This study investigated whether performing a translatable murine model of concurrent training after tumour induction affects adaptations in juvenile male and female tumour‐bearing mice. Male and female Balb/c mice were injected bilaterally with colon‐26 adenocarcinoma (C26) cells or PBS at 8 weeks of age.
Stavroula Tsitkanou +10 more
wiley +1 more source
Actomyosin-Based Nanodevices for Sensing and Actuation: Bridging Biology and Bioengineering. [PDF]
Brunet NM, Xiong P, Chase PB.
europepmc +1 more source
Abstract figure legend We developed a novel ovine model of diet‐induced maternal obesity, where ewes were fed a control or obesogenic diet for 60 days pre‐pregnancy and throughout gestation. Pregnant ewes were surgically instrumented to assess maternal cardiovascular function near term.
Rachael C. Crew +8 more
wiley +1 more source
3D muscle culture reproduces the metabolic characteristics associated with the myostatin knockout phenotype. Abstract 3D cell culture, using a variety of bioengineering techniques, enables muscle cells to be cultured in more structural and functional biomimetic conditions than 2D cell culture.
Barbara Vernus +8 more
wiley +1 more source
A novel deep intronic mutation expands the genotype spectrum of MYH7-related myopathies. [PDF]
Barp A +4 more
europepmc +1 more source
Super-relaxed myosins contribute to respiratory muscle hibernation in mechanically ventilated patients. [PDF]
van den Berg M +27 more
europepmc +1 more source
Three-stage extensive aortic substitution in a young man with a variant of uncertain significance in myosin heavy chain 11 gene. [PDF]
Pascucci F +4 more
europepmc +1 more source

