Levosimendan for patients with severely reduced left ventricular systolic function and/or low cardiac output syndrome undergoing cardiac surgery. a systematic review and meta-analysis [PDF]
Background: Previous studies have shown beneficial effects of levosimendan in high-risk patients undergoing cardiac surgery. Two large randomized controlled trials (RCTs), however, showed no advantages of levosimendan.
Arcadipane, Antonio +8 more
core +2 more sources
Predictors of low cardiac output in decompensated severe heart failure
OBJECTIVE: To identify predictors of low cardiac output and mortality in decompensated heart failure. INTRODUCTION: Introduction: Patients with decompensated heart failure have a high mortality rate, especially those patients with low cardiac output ...
Marcelo Eidi Ochiai +5 more
doaj +1 more source
Nitric oxide synthase inhibition attenuates cardiac response to hemodilution with viscogenic plasma expander. [PDF]
Background and objectivesIncreased vascular wall shear stress by elevated plasma viscosity significantly enhances the endothelial nitric oxide synthase (eNOS) activity during an acute isovolemic hemodilution.
Cabrales, Pedro, Chatpun, Surapong
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The effects of thyroid hormones levels on prognosis after pediatric heart surgery
In this study, we aimed to evaluate the effects of thyroid hormone levels on the prognosis of patients who underwent congenital heart surgery under cardiopulmonary bypass.
Engin Gurcu +3 more
doaj +1 more source
Consensus on circulatory shock and hemodynamic monitoring. Task force of the European Society of Intensive Care Medicine. [PDF]
OBJECTIVE: Circulatory shock is a life-threatening syndrome resulting in multiorgan failure and a high mortality rate. The aim of this consensus is to provide support to the bedside clinician regarding the diagnosis, management and monitoring of shock.
A Babaev +157 more
core +5 more sources
Identifying patients at risk for augmented renal clearance in the ICU : limitations and challenges [PDF]
Augmented renal clearance (ARC) is an important determinant of antibiotic exposure in critically ill patients, and identifying patients at risk is therefore an important goal.
Carlier, Mieke, De Waele, Jan
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Thermodilution vs estimated Fick cardiac output measurement in an elderly cohort of patients: A single-centre experience [PDF]
AIMS: Patients referred to the cath-lab are an increasingly elderly population. Thermodilution (TD, gold standard) and the estimated Fick method (eFM) are interchangeably used in the clinical routine to measure cardiac output (CO).
Abawi, Dawud +6 more
core +1 more source
Background: Levosimendan, a calcium sensitizer, enhances the myocardial function by generating more energy-efficient myocardial contractility than that achieved through adrenergic stimulation with catecholamines.
Hongbai Wang +5 more
doaj +1 more source
Modified Glucose-Insulin-Potassium Regimen Provides Cardioprotection With Improved Tissue Perfusion in Patients Undergoing Cardiopulmonary Bypass Surgery [PDF]
Background Laboratory studies demonstrate glucose-insulin-potassium (GIK) as a potent cardioprotective intervention, but clinical trials have yielded mixed results, likely because of varying formulas and timing of GIK treatment and different clinical ...
Chen, Wensheng +12 more
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Circulatory contributors to the phenotype in hereditary hemorrhagic telangiectasia [PDF]
Hereditary hemorrhagic telangiectasia (HHT) is mechanistically and therapeutically challenging, not only because of the molecular and cellular perturbations that generate vascular abnormalities, but also the modifications to circulatory physiology that ...
Shovlin, CL
core +2 more sources

