Results 111 to 120 of about 2,168,344 (251)

The Apparent and the Effective PR Interval, Insights for Cardiac Pacing

, 2011
A 75-year-old-male patient with dual chamber pacemaker presented with a bizarre EKG showing a unique spike within the QRS complex. Apparent PR interval was 160 ms and effective atrio- right ventricular delay was 210 ms due to right bundle branch block ...
Antoine Kossaify
core   +1 more source

Diagnostic Accuracy of 12‐Lead ECG Algorithms for Accessory Pathway Localization in WPW: A Meta‐Analysis

Pacing and Clinical Electrophysiology, EarlyView.
ABSTRACT Background In Wolff–Parkinson–White (WPW) syndrome, accurate localization of accessory pathways before catheter ablation can improve procedural planning and efficiency. Several 12‐lead electrocardiographic (ECG) algorithms have been proposed, but their diagnostic performance has not been consistently established.
Elsayed S. Moubarak, Ahmed Farid Gadelmawla, Almothana Manasrah, Anas Mansour, Mohamed S. Elgendy, Omar Elkoumi, Husam Abu Suilik, Suhaib El Khatib, Naser Albekaen, Ahmed Moustafa, Rania Samir, Islam Saboukh, Nadica Trajkovska, Angeliki Darma, Vanessa Sciacca, Thomas Fink, Moneeb Khalaph, Christian Sohns, Philipp Sommer, Hassan El‐Shirbiny   +19 more
wiley   +1 more source

Cardiomyocyte and stromal cell cross-talk influences the pathogenesis of arrhythmogenic cardiomyopathy: a multi-level analysis uncovers DLK1-NOTCH pathway role in fibro-adipose remodelling

Cell Death Discovery
Arrhythmogenic Cardiomyopathy (ACM) is a life-threatening, genetically determined disease primarily caused by mutations in desmosomal genes, such as PKP2.
Angela Serena Maione, Lara Iengo, Luca Sala, Ilaria Massaiu, Mattia Chiesa, Melania Lippi, Stefania Ghilardi, Chiara Florindi, Francesco Lodola, Antonio Zaza, Claudio Tondo, Marco Schiavone, Cristina Banfi, Giulio Pompilio, Paolo Poggio, Elena Sommariva   +15 more
doaj   +1 more source

FGF23 promotes atrial fibrillation susceptibility through ETV1‐dependent sodium channel regulation and calcium handling abnormalities

Experimental Physiology, EarlyView.
Abstract Fibroblast growth factor 23 (FGF23) is closely associated with atrial fibrillation (AF), yet whether it modulates sodium and calcium currents in atrial myocytes remains unclear. ETV1, a key transcription factor regulating atrial electrical conduction, might also be involved in FGF23‐mediated AF.
Qiaoting Yu, Linwen Zeng, Zhijie Chen, Zhuhui Lin, Congying Wang, Lan Wang, Huixian Fu, Jiancheng Zhang   +7 more
wiley   +1 more source

Caenorhabditis elegans as an in vivo model system for human inherited primary arrhythmia syndromes

The Journal of Physiology, EarlyView.
Abstract figure legend Most genes involved in inherited primary arrhythmia syndromes (IPAS) are conserved in Caenorhabditis elegans, where genetic manipulation enables functional characterization of variants, identification of regulatory proteins, and in vivo drug testing.
Antoine Delinière, Thomas Boulin, Maëlle Jospin, Alexandre Janin, Gilles Millat, Philippe Chevalier, Olga Andrini   +6 more
wiley   +1 more source

Comorbid anxiety disorders and quality of life in patients with an artificial cardiac pacemaker

Терапевтический архив, 2011
Aim. To investigate correlations between anxiety disorders, quality of life (QoL)and patient's age, mode, duration and course of cardiac pacing(CP). Material and methods.
Bakhram Guseynovich Iskenderov, Elena Vladimirovna Petrova, Dmitriy Borisovich Maksimov, Oksana Aleksandrovna Kameneva, B G Iskenderov, E V Petrova, D B Maximov, O A Kameneva   +7 more
doaj  

Advanced imaging and multi‐omics to characterize cardiomyocyte ageing and its electrocardiographic imprint in PKP2 arrhythmogenic cardiomyopathy

The Journal of Physiology, EarlyView.
Abstract figure legend We used a murine model of cardiomyocyte‐specific conditional knockout of plakophilin 2 (PKP2cKO, middle panel). Using advanced imaging technology, we unveiled distinct hallmarks of premature ageing in PKP2cKO cardiomyocytes, including DNA damage and loss of repressed heterochromatin at the nuclear periphery, and mitochondrial ...
Giorgia Bertoli, Kavya Phadke, Alessandro Cospito, Xianming Lin, Marina Cerrone, Joanna Abi Rizk, Michael Cammer, Yan Deng, Joseph Sall, Mingliang Zhang, Feng‐Xia Liang, Irene de Lázaro, Mario Delmar   +12 more
wiley   +1 more source

New Concepts in Pacemaker Syndrome [PDF]

, 2004
After implantation of a permanent pacemaker, patients may experience severe symptoms of dyspnea, palpitations, malaise, and syncope resulting from pacemaker syndrome.
Estes, Mark NA III, Farmer, Michael D, Link, Mark S   +2 more
core  

Kinematic‐calcium loops unravel impaired excitation–contraction coupling in MELAS‐affected cardioids

The Journal of Physiology, EarlyView.
Abstract figure legend Representation of kinematic and calcium transient loop with respect to traditional time coplotting. Abstract Impaired Ca2+ handling, and in particular leakage from the sarcoplasmic reticulum, is a critical mechanism in metabolic diseases affecting the heart.
Margherita Burattini, Annalinda Pisano, Maria Gemma Pignataro, Giulia d'Amati, Silvana Pinelli, Minh Long Hoang, Francesco Paolo Lo Muzio, Michele Miragoli   +7 more
wiley   +1 more source

Nationwide Lifespan Trends in Cardiac Implantable Electronic Device Strategies in Japan: Age‐Dependent Changes in Transvenous and Epicardial Systems

Journal of Arrhythmia, Volume 42, Issue 5, October 2026.
Nationwide data revealed age‐dependent differences in CIED implantation strategies. Epicardial systems remain essential in pediatric and congenital heart disease care, whereas alternative technologies are increasingly adopted in older adult populations, reflecting evolving lifespan‐related device strategies.
Aya Miyazaki, Gaku Izumi, Shuhei Fujita, Tsugutoshi Suzuki, Hiroshi Suzuki, Jun Yoshimoto, Keiko Toyohara, Yasunobu Hayabuchi, Masahiko Takagi   +8 more
wiley   +1 more source