Results 211 to 220 of about 87,451 (296)

Targeting Cell Senescence to Improve Cardiac Regeneration. [PDF]

Tex Heart Inst J, 2023
Ellison-Hughes GM.
europepmc   +1 more source

Status and future of recombinant adeno‐associated virus vector manufacturing

Biotechnology Progress, EarlyView.
Abstract Sixty years of adeno‐associated virus (AAV) research illustrates a trajectory marked by basic science exploration, iterative innovation, persistent challenges, a number of clinical setbacks, as well as commercial therapeutic triumphs. This continual evolution has led to recombinant AAV (rAAV) becoming a cornerstone of modern gene therapy ...
Frank Agbogbo, David Dismuke
wiley   +1 more source

Metabolic changes during cardiac regeneration in the axolotl. [PDF]

Dev Dyn
Dittrich A, Andersson SA, Busk M, Hansen K, Foldager CB, Palmfeldt J, Andersen A, Pedersen M, Vendelbo M, Nielsen KL, Lauridsen H.   +10 more
europepmc   +1 more source

Flap perfusion of superficial split flap design for guided bone regeneration: A case report with ultrasonography

Clinical Advances in Periodontics, EarlyView.
Abstract Background Effective flap management is crucial for successful bone regeneration procedures. Traditional flap release has been performed by the deep split design; recently, the superficial split design revives for its proposed anatomical and biomechanical advantages.
Oscar Durán‐Garnica, Karen Villarreal‐Arizpe, Amanda Rodríguez, Oliver Kripfgans, Hsun‐Liang Chan   +4 more
wiley   +1 more source

Refining the Guinea Pig (Cavia porcellus) Cryo-Injury Model for Cardiac Regeneration and Functional Characterization. [PDF]

J Am Assoc Lab Anim Sci
Nehring ME, von Bibra C, Geertz B, Roessler G, Etzion Y, Castro L, Levi O, Burg S, Hiebl B, Eschenhagen T, Weinberger F.   +10 more
europepmc   +1 more source

Cytoskeleton–Membrane Uncoupling in Duchenne Muscular Dystrophy: Implications for Newborn Screening and Early Protection

Cytoskeleton, EarlyView.
ABSTRACT The cytoskeleton of striated muscle integrates force transmission, mechanotransduction, and sarcolemmal stability through coordinated networks of sarcomeres, costameres, and intermediate filaments. Together, these systems establish mechanical continuity between the contractile apparatus, the sarcolemma, and the extracellular matrix.
Houda Cohen, Nora Hosny, Brian R. Thompson, Joseph M. Metzger   +3 more
wiley   +1 more source

The role of the extracellular matrix in cardiac regeneration. [PDF]

Heliyon
Wang X, Yu S, Xie L, Xiang M, Ma H.
europepmc   +1 more source

Investigation of the In Vitro and In Vivo Metabolism and μ‐Opioid Receptor Affinity of the Nitazene N‐Pyrrolidino Fluetonitazene

Drug Testing and Analysis, EarlyView.
Eight metabolites for N‐pyrrolidino fluetonitazene were identified in vitro, three of which (M2, M6 and M8) were present in an authentic urine sample. M2 was the most abundant in vivo metabolite and is a common marker metabolite of nitazepyne‐type substances.
Severin Zemp, Gaia Alluisetti, Wolfgang Weinmann, Bettina Schrag, Frank Sporkert, Maurine Leclerc, Katharina Elisabeth Grafinger   +6 more
wiley   +1 more source

Development, in vitro, and in vivo assessments of PCL-gelatin-βTCP fibrous scaffolds for cardiac regeneration. [PDF]

Bioimpacts
Fathi M, Baheiraei N, Moradi N, Salehi M, Zamani S, Razavi M, Eyni H.   +6 more
europepmc   +1 more source

Phase I Metabolism of Novel Phencyclidine Derivative 3‐Cl‐PCP: In Vitro Studies With Pooled Human Liver Microsomes and Investigation of a Post‐Mortem Case

Drug Testing and Analysis, EarlyView.
A fatal 3‐chloro‐phencyclidine (3‐Cl‐PCP) intoxication was investigated by analyzing postmortem samples and a pooled human liver microsomes assay. Tentative metabolite identification was performed by liquid chromatography‐quadrupole time‐of‐flight mass spectrometry (LC‐QTOF‐MS). Seven phase I metabolites were identified.
Johannes Kutzler, Tobias Veit, Thomas Keller, Volker Auwärter   +3 more
wiley   +1 more source