EIF4A3‐Induced Circular RNA circSnd1 Promotes Muscle Atrophy and Muscle Ageing by Stabilizing EEF1A1 [PDF]
Journal of Cachexia, Sarcopenia and MuscleBackground Muscle atrophy is a common complication of ageing, and many chronic conditions, lacks defined therapeutic interventions. It is still mostly unknown how circular RNAs contribute to muscle atrophy.
Jin Li +21 more
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Optineurin binding to the novel interacting partner Junction plakoglobin prevents muscle atrophy in mice. [PDF]
PLoS BiologySkeletal muscle atrophy is a debilitating condition that significantly affects patients' quality of life and prognosis, yet its underlying mechanisms remain poorly understood.
Xiao Chen Shi +10 more
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Human skeletal muscle disuse atrophy: effects on muscle protein synthesis, breakdown and insulin resistance- a qualitative review [PDF]
Frontiers in Physiology, 2016 The ever increasing burden of an ageing population and pandemic of metabolic syndrome worldwide demands further understanding of the modifiable risk factors in reducing disability and morbidity associated with these conditions.
Supreeth S Rudrappa +5 more
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Wearable Bioelectronics for Home‐Based Monitoring and Treatment of Muscle Atrophy [PDF]
Advanced ScienceMuscle atrophy is a chronic disease caused by multiple factors, and there is currently no effective treatment or reliable diagnostic method. Similar review articles focus on the induction and summary of the pathogenic mechanism and traditional treatment ...
Shuai Zhang +4 more
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Protective Effect of Delta-Like 1 Homolog Against Muscular Atrophy in a Mouse Model [PDF]
Endocrinology and Metabolism, 2022 Background Muscle atrophy is caused by an imbalance between muscle growth and wasting. Delta-like 1 homolog (DLK1), a protein that modulates adipogenesis and muscle development, is a crucial regulator of myogenic programming.
Ji Young Lee +6 more
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Denervation-induced activation of the standard proteasome and immunoproteasome [PDF]
, 2016 The standard 26S proteasome is responsible for the majority of myofibrillar protein degradation leading to muscle atrophy. The immunoproteasome is an inducible form of the proteasome.
Baumann, Cory W. +3 more
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Role of Exercise in Skeletal Muscle Atrophy: A Mechanistic Investigation [PDF]
운동과학, 2020 PURPOSE Skeletal muscle atrophy induces overall health problems and many related diseases in older adults. In particular, sarcopenia is related to lowered quality of life, decreased physical activity, high levels of morbidity and mortality owing to ...
Dae Yun Seo +3 more
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Frontiers in Cellular Neuroscience, 2021 Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related
Wenjing Ma +9 more
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Non-coding RNA basis of muscle atrophy
Molecular Therapy: Nucleic Acids, 2021 Muscle atrophy is a common complication of many chronic diseases including heart failure, cancer cachexia, aging, etc. Unhealthy habits and usage of hormones such as dexamethasone can also lead to muscle atrophy.
Qi Liu +8 more
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Interosseous muscle atrophy [PDF]
QJM, 2012 A 57-year-old woman presented with progressive upper back pain with numbness and tingling sensation over left forearm in the past 9 months. She had undergone mastectomy due to breast cancer 9 years ago and her disease relapsed 2 years ago. The physical examination revealed remarkable atrophy of interosseous muscle of left hand (Figure 1A, …
Y, Hung, M-S, Dai
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