Results 1 to 10 of about 1,110,204 (301)

Inflammation: Roles in Skeletal Muscle Atrophy

open access: yesAntioxidants, 2022
Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation, mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced proteolysis.
Yanan Ji   +11 more
doaj   +3 more sources

Polyphenols and Their Effects on Muscle Atrophy and Muscle Health

open access: yesMolecules, 2021
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced protein synthesis/accelerated protein degradation. Various conditions, such as denervation, disuse, aging, chronic diseases, heart disease, obstructive lung disease ...
Takeshi Nikawa   +2 more
doaj   +3 more sources

CircTmeff1 Promotes Muscle Atrophy by Interacting with TDP‐43 and Encoding A Novel TMEFF1‐339aa Protein

open access: yesAdvanced Science, 2023
Skeletal muscle atrophy is a common clinical feature of many acute and chronic conditions. Circular RNAs (circRNAs) are covalently closed RNA transcripts that are involved in various physiological and pathological processes, but their role in muscle ...
Rui Chen   +15 more
doaj   +2 more sources

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy [PDF]

open access: yesAdvanced Science
Disuse‐induced muscle atrophy remains a therapeutic challenge due to its complex etiology. Osteocalcin (OCN) is a bone‐derived hormone with metabolic functions, while its role in muscle atrophy remains poorly understood.
Zhaolu Wang   +5 more
doaj   +2 more sources

Protective Effect of Delta-Like 1 Homolog Against Muscular Atrophy in a Mouse Model [PDF]

open access: yesEndocrinology and Metabolism, 2022
Background Muscle atrophy is caused by an imbalance between muscle growth and wasting. Delta-like 1 homolog (DLK1), a protein that modulates adipogenesis and muscle development, is a crucial regulator of myogenic programming.
Ji Young Lee   +6 more
doaj   +1 more source

Role of Exercise in Skeletal Muscle Atrophy: A Mechanistic Investigation [PDF]

open access: yes운동과학, 2020
PURPOSE Skeletal muscle atrophy induces overall health problems and many related diseases in older adults. In particular, sarcopenia is related to lowered quality of life, decreased physical activity, high levels of morbidity and mortality owing to ...
Dae Yun Seo   +3 more
doaj   +1 more source

HDAC4 Knockdown Alleviates Denervation-Induced Muscle Atrophy by Inhibiting Myogenin-Dependent Atrogene Activation

open access: yesFrontiers in Cellular Neuroscience, 2021
Denervation can activate the catabolic pathway in skeletal muscle and lead to progressive skeletal muscle atrophy. At present, there is no effective treatment for muscle atrophy. Histone deacetylase 4 (HDAC4) has recently been found to be closely related
Wenjing Ma   +9 more
doaj   +1 more source

Non-coding RNA basis of muscle atrophy

open access: yesMolecular Therapy: Nucleic Acids, 2021
Muscle atrophy is a common complication of many chronic diseases including heart failure, cancer cachexia, aging, etc. Unhealthy habits and usage of hormones such as dexamethasone can also lead to muscle atrophy.
Qi Liu   +8 more
doaj   +1 more source

Zebrafish Model for Studying Dexamethasone-Induced Muscle Atrophy and Preventive Effect of Maca (Lepidium meyenii)

open access: yesCells, 2021
Loss of myofibers during muscle atrophy affects functional capacity and quality of life. Dexamethasone, an inducer of rapid atrophy of skeletal myofibers, has been studied as a glucocorticoid receptor in muscle atrophy or motor neurodegeneration. In this
Bomi Ryu   +3 more
doaj   +1 more source

Cold-induced muscle atrophy in zebrafish: Insights from swimming activity and gene expression analysis

open access: yesBiochemistry and Biophysics Reports, 2023
The investigation into the effects of cold acclimation on fish skeletal muscle function and its potential implications for muscle atrophy is of great interest to us.
Daisuke Ikeda   +5 more
doaj   +1 more source

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