Results 31 to 40 of about 1,110,204 (301)

UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. [PDF]

, 2019
We aimed to investigate a novel and uncharacterised E3 ubiquitin ligase in skeletal muscle atrophy, recovery from atrophy/injury, anabolism and hypertrophy.

core   +1 more source

Peroxisome proliferator-activated receptor-γ coactivator-1α in muscle links metabolism to inflammation [PDF]

, 2009
1. In higher eukaryotes, metabolism and immunity are tightly coupled. However, whereas evolutionary, a compromised immune response due to undernourishment has been the predominant problem, the inflammatory response to obesity and other life style ...
Handschin, C., Handschin, C
core   +1 more source

Mitochondrial dysfunction: roles in skeletal muscle atrophy

Journal of Translational Medicine, 2023
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle health, and damage to mitochondria can lead to a series of pathophysiological changes.
Xin Chen, Yanan Ji, Ruiqi Liu, Xucheng Zhu, Kexin Wang, Xiaoming Yang, Boya Liu, Zihui Gao, Yan Huang, Yuntian Shen, Hua Liu, Hualin Sun   +11 more
doaj   +1 more source

Coexistence of muscle atrophy and high subcutaneous adipose tissue radiodensity predicts poor prognosis in hepatocellular carcinoma

Frontiers in Nutrition, 2023
IntroductionWe aimed to assess the prognostic implications of muscle atrophy and high subcutaneous adipose tissue (SAT) radiodensity in patients with hepatocellular carcinoma (HCC).MethodsIn this retrospective study, muscle atrophy was assessed using the
Masatsugu Ohara, Goki Suda, Risako Kohya, Takashi Sasaki, Tomoka Yoda, Sonoe Yoshida, Qingjie Fu, Zijian Yang, Shunichi Hosoda, Osamu Maehara, Shunsuke Ohnishi, Yoshimasa Tokuchi, Takashi Kitagataya, Naoki Kawagishi, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Koji Ogawa, Naoya Sakamoto   +18 more
doaj   +1 more source

Castor Oil Plant (Ricinus communis L.) Leaves Improve Dexamethasone-Induced Muscle Atrophy via Nrf2 Activation

Frontiers in Pharmacology, 2022
Skeletal muscle atrophy is characterized by reduced muscle function and size. Oxidative stress contributes to muscle atrophy but can be treated with antioxidants.
Hyunjung Lee, Young In Kim, Min Jung Kim, Jeong-Hoon Hahm, Hyo Deok Seo, Tae Youl Ha, Tae Youl Ha, Chang Hwa Jung, Chang Hwa Jung, Jiyun Ahn, Jiyun Ahn   +10 more
doaj   +1 more source

Role of microRNA in muscle regeneration and diseases related to muscle dysfunction in atrophy, cachexia, osteoporosis, and osteoarthritis [PDF]

, 2020
MicroRNAs (miRNAs) are a class of small non-coding RNAs that have emerged as potential predictive, prognostic, and therapeutic biomarkers, relevant to many pathophysiological conditions including limb immobilization, osteoarthritis, sarcopenia, and ...
Hamilton, David F., McGregor, Robin, Simpson, A. Hamish R.W., Brzeszczy?ski, Filip, Brzeszczy?ska, Joanna   +4 more
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Muscle Atrophy With Tabes [PDF]

The Journal of Nervous and Mental Disease, 1905
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openaire   +1 more source

The role of microRNAs in dexamethasone-induced skeletal muscle atrophy

Experimental Gerontology
Muscle atrophy is characterized by a decrease in muscle mass, strength, and activity. Recently, it was determined that microRNAs (miRNAs) can regulate muscle atrophy and that dexamethasone (Dex), an allergy and autoimmune disorder treatment that can ...
Subi Ren, Jie Chai, Lijuan Zhang, JiGang Li, Xi Long, Tinghuan Zhang   +5 more
doaj   +1 more source

Curcuma longa L. Water Extract Improves Dexamethasone-Induced Sarcopenia by Modulating the Muscle-Related Gene and Oxidative Stress in Mice

Antioxidants, 2021
Dexamethasone (DEX) promotes proteolysis, which causes muscle atrophy. Muscle atrophy is connected to sarcopenia. We evaluated the effect of Curcuma longa L. water extract (CLW) on DEX-induced muscle atrophy.
Shintae Kim, Kyungmi Kim, Jeongjin Park, Woojin Jun   +3 more
doaj   +1 more source

FRET‐Based Sensor Zebrafish Reveal Muscle Cells Do Not Undergo Apoptosis in Starvation or Natural Aging‐Induced Muscle Atrophy

Advanced Science
Muscle atrophy occurs during natural aging and under disease conditions. Muscle cell apoptosis is considered one of the main causes of muscle atrophy, while several recent studies argued that muscle cells do not die during muscle atrophy.
Hao Jia, Renfei Wu, Hongmei Yang, Kathy Qian Luo   +3 more
doaj   +1 more source