Results 21 to 30 of about 1,927,947 (250)

Handelin alleviates cachexia‐ and aging‐induced skeletal muscle atrophy by improving protein homeostasis and inhibiting inflammation

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2023
Handelin is a bioactive compound from Chrysanthemum indicum L. that improves motor function and muscle integrity during aging in Caenorhabditis elegans. This study aimed to further evaluate the protective effects and molecular mechanisms of handelin in a
Hui-jie Zhang   +11 more
semanticscholar   +1 more source

Mechanism of skeletal muscle atrophy after spinal cord injury: A narrative review

open access: yesFrontiers in Nutrition, 2023
Spinal cord injury leads to loss of innervation of skeletal muscle, decreased motor function, and significantly reduced load on skeletal muscle, resulting in atrophy.
Xin Xu   +12 more
semanticscholar   +1 more source

Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway

open access: yesNature Communications, 2023
To maintain and restore skeletal muscle mass and function is essential for healthy aging. We have found that myonectin acts as a cardioprotective myokine.
Yuta Ozaki   +17 more
doaj   +1 more source

The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy

open access: yesCells, 2022
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condition that ...
Keisuke Hitachi   +2 more
doaj   +1 more source

Interosseous muscle atrophy [PDF]

open access: yesQJM, 2012
A 57-year-old woman presented with progressive upper back pain with numbness and tingling sensation over left forearm in the past 9 months. She had undergone mastectomy due to breast cancer 9 years ago and her disease relapsed 2 years ago. The physical examination revealed remarkable atrophy of interosseous muscle of left hand (Figure 1A, …
Y, Hung, M-S, Dai
openaire   +2 more sources

Chronic Kidney Disease-induced Muscle Atrophy: Molecular Mechanisms and Promising Therapies.

open access: yesBiochemical Pharmacology, 2022
Chronic kidney disease (CKD) is a high-risk chronic catabolic disease due to its high morbidity and mortality. CKD is accompanied by many complications, leading to a poor quality of life, and serious complications may even threaten the life of CKD ...
Kexin Wang   +11 more
semanticscholar   +1 more source

Therapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model

open access: yesPharmaceuticals, 2023
Skeletal muscle atrophy is associated with poor quality of life and disability. Thus, finding a new strategy for the prevention and treatment of skeletal muscle atrophy is very crucial.
Seyedeh Elnaz Nazari   +7 more
doaj   +1 more source

The Vitamin D/Vitamin D receptor (VDR) axis in muscle atrophy and sarcopenia.

open access: yesCellular Signalling, 2022
Muscle atrophy and sarcopenia (the term given to the age-related decline in muscle mass and function), influence an individuals risk of falls, frailty, functional decline, and, ultimately, impaired quality of life.
S. Bollen   +5 more
semanticscholar   +1 more source

FOXO signaling pathway in skeletal muscle atrophy.

open access: yesAmerican Journal of Pathology, 2022
Skeletal muscle atrophy is the consequence of protein degradation exceeding protein synthesis due to disease, aging and physical inactivity. Patients with skeletal muscle atrophy have decreased muscle mass and fiber cross-sectional area, thereby ...
Kun Chen   +8 more
semanticscholar   +1 more source

Butyrate ameliorates skeletal muscle atrophy in diabetic nephropathy by enhancing gut barrier function and FFA2‐mediated PI3K/Akt/mTOR signals

open access: yesBritish Journal of Pharmacology, 2021
Muscle protein catabolism in patients with diabetic nephropathy (DN) results in striking loss of muscle proteins, which increases morbidity and mortality risks.
Gang Tang   +7 more
semanticscholar   +1 more source

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