Results 11 to 20 of about 286,203 (303)

Inflammation: Roles in Skeletal Muscle Atrophy

open access: yesAntioxidants, 2022
Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation, mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced proteolysis.
Yanan Ji   +11 more
doaj   +3 more sources

Molecular Mechanisms of Muscle Atrophy [PDF]

open access: yesCell, 2004
Skeletal muscle atrophy has extreme adverse consequences. Molecular mechanisms that mediate the process of atrophy are not well defined. Recent studies have focused on diverse molecular cascades that control the activation of ubiquitin ligases, indicating that the involvement of the ubiquitin proteasome may be common to a range of atrophic stimuli.
McKinnell, Iain W., Rudnicki, Michael A.
openaire   +4 more sources

Zebrafish Model for Studying Dexamethasone-Induced Muscle Atrophy and Preventive Effect of Maca (Lepidium meyenii)

open access: yesCells, 2021
Loss of myofibers during muscle atrophy affects functional capacity and quality of life. Dexamethasone, an inducer of rapid atrophy of skeletal myofibers, has been studied as a glucocorticoid receptor in muscle atrophy or motor neurodegeneration. In this
Bomi Ryu   +3 more
doaj   +1 more source

Angiotensin II-induced muscle atrophy via PPARγ suppression is mediated by miR-29b

open access: yesMolecular Therapy: Nucleic Acids, 2021
The activation of the renin-angiotensin system (RAS) induced by increased angiotensin II (AngII) levels has been implicated in muscle atrophy, which is involved in the pathogenesis of congestive heart failure.
Jin Li   +12 more
doaj   +1 more source

Identification of potential microRNAs and KEGG pathways in denervation muscle atrophy based on meta-analysis

open access: yesScientific Reports, 2021
The molecular mechanism of muscle atrophy has been studied a lot, but there is no comprehensive analysis focusing on the denervated muscle atrophy. The gene network that controls the development of denervated muscle atrophy needs further elucidation.
Xinyi Gu   +3 more
doaj   +1 more source

Cold-induced muscle atrophy in zebrafish: Insights from swimming activity and gene expression analysis

open access: yesBiochemistry and Biophysics Reports, 2023
The investigation into the effects of cold acclimation on fish skeletal muscle function and its potential implications for muscle atrophy is of great interest to us.
Daisuke Ikeda   +5 more
doaj   +1 more source

Myonectin protects against skeletal muscle dysfunction in male mice through activation of AMPK/PGC1α pathway

open access: yesNature Communications, 2023
To maintain and restore skeletal muscle mass and function is essential for healthy aging. We have found that myonectin acts as a cardioprotective myokine.
Yuta Ozaki   +17 more
doaj   +1 more source

The Functional Role of Long Non-Coding RNA in Myogenesis and Skeletal Muscle Atrophy

open access: yesCells, 2022
Skeletal muscle is a pivotal organ in humans that maintains locomotion and homeostasis. Muscle atrophy caused by sarcopenia and cachexia, which results in reduced muscle mass and impaired skeletal muscle function, is a serious health condition that ...
Keisuke Hitachi   +2 more
doaj   +1 more source

Therapeutic Potential of Hydrogen-Rich Water on Muscle Atrophy Caused by Immobilization in a Mouse Model

open access: yesPharmaceuticals, 2023
Skeletal muscle atrophy is associated with poor quality of life and disability. Thus, finding a new strategy for the prevention and treatment of skeletal muscle atrophy is very crucial.
Seyedeh Elnaz Nazari   +7 more
doaj   +1 more source

Polyphenols and Their Effects on Muscle Atrophy and Muscle Health

open access: yesMolecules, 2021
Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced protein synthesis/accelerated protein degradation. Various conditions, such as denervation, disuse, aging, chronic diseases, heart disease, obstructive lung disease ...
Takeshi Nikawa   +2 more
doaj   +1 more source

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