Results 11 to 20 of about 1,166,632 (295)
Inflammation: Roles in Skeletal Muscle Atrophy
Antioxidants, 2022 Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation, mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced proteolysis.
Yuntian Shen, Hualin Sun, Yanan Ji
exaly +4 more sources
Non-coding RNA basis of muscle atrophy
Molecular Therapy - Nucleic Acids, 2021 Muscle atrophy is a common complication of many chronic diseases including heart failure, cancer cachexia, aging, etc. Unhealthy habits and usage of hormones such as dexamethasone can also lead to muscle atrophy.
Yan Qiu, Jiali Deng, Yan Qiu
exaly +3 more sources
Polyphenols and Their Effects on Muscle Atrophy and Muscle Health
Molecules, 2021 Skeletal muscle atrophy is the decrease in muscle mass and strength caused by reduced protein synthesis/accelerated protein degradation. Various conditions, such as denervation, disuse, aging, chronic diseases, heart disease, obstructive lung disease ...
Anayt Ulla, Takeshi Nikawa
exaly +3 more sources
Advanced Science, 2023 Skeletal muscle atrophy is a common clinical feature of many acute and chronic conditions. Circular RNAs (circRNAs) are covalently closed RNA transcripts that are involved in various physiological and pathological processes, but their role in muscle ...
Junjie Xiao, Hongjian Chen, Yuwei Yan
exaly +2 more sources
Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy [PDF]
Advanced ScienceDisuse‐induced muscle atrophy remains a therapeutic challenge due to its complex etiology. Osteocalcin (OCN) is a bone‐derived hormone with metabolic functions, while its role in muscle atrophy remains poorly understood.
Zhaolu Wang +5 more
doaj +2 more sources
Advanced ScienceLittle is known about if and how circular RNAs (circRNAs) are involved in skeletal muscle atrophy. Here a conserved circular RNA Damage‐specific DNA binding protein 1 (circDdb1), derived from the host gene encoding Damage‐specific DNA binding protein 1 ...
Junjie Xiao, Emeli Chatterjee, Yuwei Yan
exaly +2 more sources
Protective Effect of Delta-Like 1 Homolog Against Muscular Atrophy in a Mouse Model [PDF]
Endocrinology and Metabolism, 2022 Background Muscle atrophy is caused by an imbalance between muscle growth and wasting. Delta-like 1 homolog (DLK1), a protein that modulates adipogenesis and muscle development, is a crucial regulator of myogenic programming.
Ji Young Lee +6 more
doaj +1 more source
Epigenetics of Skeletal Muscle Atrophy
International Journal of Molecular SciencesSkeletal muscle atrophy, characterized by diminished muscle strength and mass, arises from various causes, including malnutrition, aging, nerve damage, and disease-related secondary atrophy. Aging markedly escalates the prevalence of sarcopenia. Concurrently, the incidence of muscle atrophy significantly rises among patients with chronic ailments such ...
Jiacheng Du, Qian Wu, Eun Ju Bae
openaire +3 more sources
Role of Exercise in Skeletal Muscle Atrophy: A Mechanistic Investigation [PDF]
운동과학, 2020 PURPOSE Skeletal muscle atrophy induces overall health problems and many related diseases in older adults. In particular, sarcopenia is related to lowered quality of life, decreased physical activity, high levels of morbidity and mortality owing to ...
Dae Yun Seo +3 more
doaj +1 more source
Development of Therapies for Spinal Muscular Atrophy Using Gene Therapy and Nanotechnology [PDF]
, 2013 Spinal muscular atrophy (SMA) is a genetic disease which is characterized by muscle weakness and atrophy. The disease arises from mutations in the survival motor neuron 1 (SMN1) gene causing degeneration of spinal cord motor neurons.
Little, Daniel
core +5 more sources