Results 41 to 50 of about 1,166,632 (295)

UBR5 is a novel E3 ubiquitin ligase involved in skeletal muscle hypertrophy and recovery from atrophy. [PDF]

open access: yes, 2019
We aimed to investigate a novel and uncharacterised E3 ubiquitin ligase in skeletal muscle atrophy, recovery from atrophy/injury, anabolism and hypertrophy.

core   +1 more source

Mitochondrial dysfunction: roles in skeletal muscle atrophy

open access: yesJournal of Translational Medicine, 2023
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle health, and damage to mitochondria can lead to a series of pathophysiological changes.
Xin Chen   +11 more
doaj   +1 more source

Pyruvate dehydrogenase kinase 4 promotes ubiquitin–proteasome system‐dependent muscle atrophy

open access: yesJournal of Cachexia, Sarcopenia and Muscle, 2022
Background Muscle atrophy, leading to muscular dysfunction and weakness, is an adverse outcome of sustained period of glucocorticoids usage. However, the molecular mechanism underlying this detrimental condition is currently unclear.
Ibotombi Singh Sinam   +12 more
doaj   +1 more source

Coexistence of muscle atrophy and high subcutaneous adipose tissue radiodensity predicts poor prognosis in hepatocellular carcinoma

open access: yesFrontiers in Nutrition, 2023
IntroductionWe aimed to assess the prognostic implications of muscle atrophy and high subcutaneous adipose tissue (SAT) radiodensity in patients with hepatocellular carcinoma (HCC).MethodsIn this retrospective study, muscle atrophy was assessed using the
Masatsugu Ohara   +18 more
doaj   +1 more source

Myogenin regulates denervation‐dependent muscle atrophy in mouse soleus muscle [PDF]

open access: yes, 2011
Muscle inactivity due to injury or disease results in muscle atrophy. The molecular mechanisms contributing to muscle atrophy are poorly understood. However, it is clear that expression of atrophy‐related genes, like Atrogin‐1 and MuRF‐1, are intimately ...
Macpherson, Peter C. D.   +5 more
core   +1 more source

Muscle Atrophy With Tabes [PDF]

open access: yesThe Journal of Nervous and Mental Disease, 1905
n ...
openaire   +1 more source

Function of mTOR complex 1 and 2 in skeletal muscle [PDF]

open access: yes, 2009
Growth of an organ during development and during adaptation in the adult can be controlled by alterations either in the number or the size of cells. The two mechanisms are fundamentally different and require distinct regulation.
Bentzinger, Conrad Florian
core   +1 more source

A functional motor unit in the culture dish : co-culture of spinal cord explants and muscle cells [PDF]

open access: yes, 2012
Human primary muscle cells cultured aneurally in monolayer rarely contract spontaneously because, in the absence of a nerve component, cell differentiation is limited and motor neuron stimulation is missing(1). These limitations hamper the in vitro study
Handschin, Christoph   +5 more
core   +1 more source

The role of microRNAs in dexamethasone-induced skeletal muscle atrophy

open access: yesExperimental Gerontology
Muscle atrophy is characterized by a decrease in muscle mass, strength, and activity. Recently, it was determined that microRNAs (miRNAs) can regulate muscle atrophy and that dexamethasone (Dex), an allergy and autoimmune disorder treatment that can ...
Subi Ren   +5 more
doaj   +1 more source

Castor Oil Plant (Ricinus communis L.) Leaves Improve Dexamethasone-Induced Muscle Atrophy via Nrf2 Activation

open access: yesFrontiers in Pharmacology, 2022
Skeletal muscle atrophy is characterized by reduced muscle function and size. Oxidative stress contributes to muscle atrophy but can be treated with antioxidants.
Hyunjung Lee   +10 more
doaj   +1 more source

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