Results 41 to 50 of about 1,927,947 (250)

Coexistence of muscle atrophy and high subcutaneous adipose tissue radiodensity predicts poor prognosis in hepatocellular carcinoma

Frontiers in Nutrition, 2023
IntroductionWe aimed to assess the prognostic implications of muscle atrophy and high subcutaneous adipose tissue (SAT) radiodensity in patients with hepatocellular carcinoma (HCC).MethodsIn this retrospective study, muscle atrophy was assessed using the
Masatsugu Ohara, Goki Suda, Risako Kohya, Takashi Sasaki, Tomoka Yoda, Sonoe Yoshida, Qingjie Fu, Zijian Yang, Shunichi Hosoda, Osamu Maehara, Shunsuke Ohnishi, Yoshimasa Tokuchi, Takashi Kitagataya, Naoki Kawagishi, Masato Nakai, Takuya Sho, Mitsuteru Natsuizaka, Koji Ogawa, Naoya Sakamoto   +18 more
doaj   +1 more source

Human skeletal muscle-specific atrophy with aging: a comprehensive review.

Journal of applied physiology, 2023
Age-related skeletal muscle atrophy appears to be a muscle group-specific process, yet only a few specific muscles have been investigated and our understanding in this area is limited.
M. Naruse, Scott Trappe, T. Trappe
semanticscholar   +1 more source

Muscle Atrophy With Tabes [PDF]

The Journal of Nervous and Mental Disease, 1905
n ...
openaire   +1 more source

Nutrients against Glucocorticoid-Induced Muscle Atrophy

Foods, 2022
Glucocorticoid excess is a critical factor contributing to muscle atrophy. Both endogenous and exogenous glucocorticoids negatively affect the preservation of muscle mass and function. To date, the most effective intervention to prevent muscle atrophy is
Min-Kyeong Lee, Hyeon Hak Jeong, Myeong-Jin Kim, Hee-won Ryu, J. Baek, Bonggi Lee   +5 more
semanticscholar   +1 more source

Castor Oil Plant (Ricinus communis L.) Leaves Improve Dexamethasone-Induced Muscle Atrophy via Nrf2 Activation

Frontiers in Pharmacology, 2022
Skeletal muscle atrophy is characterized by reduced muscle function and size. Oxidative stress contributes to muscle atrophy but can be treated with antioxidants.
Hyunjung Lee, Young In Kim, Min Jung Kim, Jeong-Hoon Hahm, Hyo Deok Seo, Tae Youl Ha, Tae Youl Ha, Chang Hwa Jung, Chang Hwa Jung, Jiyun Ahn, Jiyun Ahn   +10 more
doaj   +1 more source

Metformin induces muscle atrophy by transcriptional regulation of myostatin via HDAC6 and FoxO3a

Journal of Cachexia, Sarcopenia and Muscle, 2021
Skeletal muscle atrophy is a severe condition that involves loss of muscle mass and quality. Drug intake can also cause muscle atrophy. Biguanide metformin is the first‐line and most widely prescribed anti‐diabetic drug for patients with type 2 diabetes.
Min Ju Kang, J. Moon, J. O. Lee, J. H. Kim, Eun-Jeong Jung, S. J. Kim, J. Oh, Sang Woo Wu, P. Lee, Sun Hwa Park, Hyeon Soo Kim   +10 more
semanticscholar   +1 more source

The role of mitochondrial dynamics and mitophagy in skeletal muscle atrophy: from molecular mechanisms to therapeutic insights

Cellular & Molecular Biology Letters
Skeletal muscle is the largest metabolic organ of the human body. Maintaining the best quality control and functional integrity of mitochondria is essential for the health of skeletal muscle.
Yuhang Lei, M. Gan, Yanhao Qiu, Qiuyang Chen, Xingyu Wang, Tianci Liao, Mengying Zhao, Lei Chen, Shunhua Zhang, Ye Zhao, L. Niu, Yan Wang, Li Zhu, Linyuan Shen   +13 more
semanticscholar   +1 more source

Integrated genomic and proteomic analyses identify stimulus-dependent molecular changes associated with distinct modes of skeletal muscle atrophy

Cell Reports, 2021
SUMMARY Skeletal muscle atrophy is a debilitating condition that occurs with aging and disease, but the underlying mechanisms are incompletely understood. Previous work determined that common transcriptional changes occur in muscle during atrophy induced
Liam C Hunt, F. Graça, V. Pagala, Yong-Dong Wang, Yuxin Li, Zuo-Fei Yuan, Yiping Fan, Myriam Labelle, Junmin Peng, Fabio Demontis   +9 more
semanticscholar   +1 more source

The role of microRNAs in dexamethasone-induced skeletal muscle atrophy

Experimental Gerontology
Muscle atrophy is characterized by a decrease in muscle mass, strength, and activity. Recently, it was determined that microRNAs (miRNAs) can regulate muscle atrophy and that dexamethasone (Dex), an allergy and autoimmune disorder treatment that can ...
Subi Ren, Jie Chai, Lijuan Zhang, JiGang Li, Xi Long, Tinghuan Zhang   +5 more
doaj   +1 more source

Curcuma longa L. Water Extract Improves Dexamethasone-Induced Sarcopenia by Modulating the Muscle-Related Gene and Oxidative Stress in Mice

Antioxidants, 2021
Dexamethasone (DEX) promotes proteolysis, which causes muscle atrophy. Muscle atrophy is connected to sarcopenia. We evaluated the effect of Curcuma longa L. water extract (CLW) on DEX-induced muscle atrophy.
Shintae Kim, Kyungmi Kim, Jeongjin Park, Woojin Jun   +3 more
doaj   +1 more source