Results 251 to 260 of about 160,558 (349)

Targeting miRNA-1a and miRNA-15b: A Novel Combinatorial Strategy to Drive Adult Cardiac Regeneration. [PDF]

Adv Sci (Weinh)
Yuan T, Wu M, Zhu C, Yu H, Pham MD, Bottermann K, Mao Y, Wang Y, Langner M, Peitzsch M, Das AP, Kauferstein S, Ward J, Mirtschink P, Zeiher AM, Dimmeler S, Krishnan J.   +16 more
europepmc   +1 more source

Phocaeicola coprophilus‐Derived 6‐Methyluracil Attenuates Radiation‐Induced Intestinal Fibrosis by Suppressing the IDO1‐Kynurenine‐AHR Axis

Advanced Science, EarlyView.
IR‐induced dysbiosis depletes P. coprophilus and its metabolite 6‐methyluracil, leading to disinhibition of the IDO1‐Kyn‐AHR axis. This results in sustained fibroblast activation and collagen deposition, driving radiation induced intestinal fibrosis. ABSTRACT Therapeutic options for radiation‐induced intestinal fibrosis (RIF) remain limited. This study
Jiaxin Zhang, Zhen Wang, Shuang Li, Chao Luo, Han Li, Shengjie Ma, Pai Wang, Heshi Liu, Lijun Sun, Yue Yin, Weizhen Zhang, Quan Wang   +11 more
wiley   +1 more source

Tissue extracellular vesicles suppress neonatal cardiac regeneration: a Pak2-Erk1/2-mediated macrophage paracrine signaling. [PDF]

Acta Biochim Biophys Sin (Shanghai)
Li Y, Zhang L, Wu Y, Wei L, Zhang Z, Mo H, Liu Z, Wang X, Shen Y, Zhu H.   +9 more
europepmc   +1 more source

Author response: Reciprocal analyses in zebrafish and medaka reveal that harnessing the immune response promotes cardiac regeneration

, 2017
Shih-Lei Lai, Rubén Marín‐Juez, Pedro Luís Moura, Carsten Kuenne, Jason Lai, Ayele Taddese Tsedeke, Stefan Günther, Mario Looso, Didier Y. R. Stainier   +8 more
openalex   +1 more source

Substituent‐Based Modulation of Self‐Assembly and Immunogenicity of Amphipathic Peptides

Advanced Science, EarlyView.
This study systematically investigates how positional and subtle changes, such as substituents on the phenyl ring attached to short amphipathic peptides, influence their self‐assembly, fibril morphology, and immunogenic responses. ABSTRACT Self‐assembled peptide‐based biomaterials provide versatile platforms for biomedical uses, featuring customizable ...
Anirban Das, Ushasi Pramanik, Elise M. Brown, Chih‐Yun Liu, Huan Gong, Jonathan Fascetti, Mark Gibson, Samuel Stealey, Silviya P. Zustiak, Cory Berkland, Piyoosh Sharma, Meredith E. Jackrel, Mark A. White, Jai S. Rudra   +13 more
wiley   +1 more source

The sphinx helps to answer the riddle of cardiac regeneration. [PDF]

Trends Endocrinol Metab
Jung JW, Hla T, Arany Z.
europepmc   +1 more source

Rationale and Design of the CONCERT-HF Trial (Combination of Mesenchymal and c-kit ⁺ Cardiac Stem Cells As Regenerative Therapy for Heart Failure) [PDF]

, 2018
Roberto Bolli, Joshua M. Hare, Keith L. March, Carl J. Pepine, James T. Willerson, Emerson C. Perin, Phillip C. Yang, Timothy D. Henry, Jay H. Traverse, Raul D. Mitrani, Aisha Khan, Ivonne Hernandez Schulman, Doris A. Taylor, Darcy L. DiFede, João A.C. Lima, Atul Chugh, John Loughran, Rachel W. Vojvodic, Shelly L. Sayre, Judy Bettencourt, Michelle Cohen, Lem Moyé, Ray F. Ebert, Robert D. Simari   +23 more
openalex   +1 more source

Microgel‐Based Hierarchical Porous Hydrogel Patch with Adhesion and Resilience for Myocardial Infarction

Advanced Science, EarlyView.
This study develops a hierarchically porous hydrogel patch strategy (HPMP), based on gas‐shearing microfluidics and an aqueous two‐phase system to fabricate porous microgels as microgel‐based bioinks. The porous microgels with controllable porous structure exhibit excellent cellular behavior.
Ziyang Liu, Leyan Xuan, Yingying Hou, Ting Xie, Jieting Li, Junjie Cai, Siyu Zhang, Yingling Miao, Ning Hou, Gen He, Maobin Xie, Xiyong Yu, Mingen Xu, Guosheng Tang   +13 more
wiley   +1 more source

Mechanistic insights into cardiac regeneration and protection through MEIS inhibition. [PDF]

Turk J Biol
Mammadova A, Aslan GS, Mo L, Wu Q, Clauss S, Kocabaş F.   +5 more
europepmc   +1 more source

Multifunctional E‐Tattoos Based on Electrospun PVBVA Fibers Coated with Ti3C2Tx MXene for Energy Harvesting, Energy Storage, and Biometric Sensing

Advanced Science, EarlyView.
This study explores a novel E‐tattoo made from PVBVA fibers coated with Ti3C2Tx MXene. The device is designed to harvest energy directly from the human body, providing power for itself. The research demonstrates the E‐tattoo's capability for charge storage and its potential for health monitoring through integrated ECG and EMG sensing, all within a ...
Ajay Pratap, Fereshteh Rajabi Kouchi, Tony Valayil‐Varghese, Hailey Burgoyne, Attila Rektor, Michael Curtis, Miranda Lea Nelson, Francis N. Mokogwu, Corey M. Efaw, Josh Eixenberger, Allyssa Bateman, Benjamin C. Johnson, Brian Jaques, Zhangxian Deng, Kurtis Cantley, Christopher E. Shuck, David Estrada   +16 more
wiley   +1 more source