Results 271 to 280 of about 87,451 (296)
MicroRNAs and Cardiac Regeneration [PDF]
Circulation Research, 2015 The human heart has a limited capacity to regenerate lost or damaged cardiomyocytes after cardiac insult. Instead, myocardial injury is characterized by extensive cardiac remodeling by fibroblasts, resulting in the eventual deterioration of cardiac structure and function.
Martin H Kang +2 more
exaly +3 more sources
Some of the next articles are maybe not open access.
Related searches:
Related searches:
Cardiac Regeneration in Children
Pediatric Cardiology, 2015Very young mammals have an impressive cardiac regeneration capacity. In contrast, cardiac regeneration is very limited in adult humans. The hearts of young children have a higher regenerative capacity compared with adults, as, for example, seen after surgical correction of an anomalous left coronary artery arising from the pulmonary artery or in ...
Stefan, Rupp, Dietmar, Schranz
openaire +2 more sources
An emerging consensus on cardiac regeneration [PDF]
Nature Medicine, 2014 Cardiac regeneration is a rapidly evolving and controversial field of research. The identification some 12 years ago of progenitor cells that reside within the heart spurred enthusiasm for cell-based regenerative therapies. However, recent evidence has called into question both the presence of a biologically important stem cell population in the heart ...
Jop Van Berlo +2 more
exaly +3 more sources
CARDIAC REGENERATION: Repopulating the Heart
Annual Review of Physiology, 2006▪ Abstract Many forms of pediatric and adult heart disease result from a deficiency in cardiomyocyte number. Through repopulation of the heart with new cardiomyocytes (that is, induction of regenerative cardiac growth), cardiac disease potentially can be reversed, provided that the newly formed myocytes structurally and functionally integrate in the ...
Michael, Rubart, Loren J, Field
openaire +2 more sources
MicroRNA Therapeutics for Cardiac Regeneration
Mini-Reviews in Medicinal Chemistry, 2015It is estimated that a typical myocardial infarction results in the loss of approximately one billion functional cardiomyocytes, which are replaced by a non-contractile fibrous scar, eventually leading to heart failure. The currently available surgical, drug, and device-based therapies cannot reverse the loss of functional myocardium, which is the ...
Zhiyong, Lei +2 more
openaire +2 more sources
Hydrogels for cardiac tissue regeneration
Bio-Medical Materials and Engineering, 2008Our research is focused on the design of engineered biomaterials that can harness natural cellular and molecular healing pathways to enhance functional tissue regeneration. Two important considerations for tissue regeneration are induction and remodeling.
Keren, Shapira +4 more
openaire +2 more sources
microRNAs in cardiac development and regeneration
Clinical Science, 2013Heart development involves the precise orchestration of gene expression during cardiac differentiation and morphogenesis by evolutionarily conserved regulatory networks. miRNAs (microRNAs) play important roles in the post-transcriptional regulation of gene expression, and recent studies have established critical functions for these tiny RNAs in almost ...
openaire +5 more sources
The evolving cardiac lymphatic vasculature in development, repair and regeneration
Nature Reviews Cardiology, 2021Konstantinos Klaourakis +2 more
exaly