Results 271 to 280 of about 157,414 (301)
Some of the next articles are maybe not open access.
Cardiac regeneration therapy: connections to cardiac physiology
American Journal of Physiology-Heart and Circulatory Physiology, 2011Without heart transplantation, a large number of patients with failing hearts worldwide face poor outcomes. By means of cardiomyocyte regeneration, cardiac regeneration therapy is emerging with great promise as a means for restoring loss of cardiac function.
Naofumi, Takehara, Hiroaki, Matsubara
openaire +2 more sources
Experimental models for cardiac regeneration
Nature Clinical Practice Cardiovascular Medicine, 2006Simple ex vivo or in vitro models are most useful for testing putative cell therapy protocols, as they allow quick and controlled screening of variants and possible improvements. We discuss here three different models: coculture of precursors of human bone marrow cells (BMCs) with mouse heart slices bearing a cryogenic lesion; coculture of human BMCs ...
Ana, Sánchez +6 more
openaire +2 more sources
Cardiac regeneration: messages from CADUCEUS
The Lancet, 2012link_to_subscribed_fulltext
Siu, CW, Tse, HF
openaire +4 more sources
Endogenous Mechanisms of Cardiac Regeneration
2016Zebrafish possess a remarkable capacity for cardiac regeneration throughout their lifetime, providing a model for investigating endogenous cellular and molecular mechanisms regulating myocardial regeneration. By contrast, adult mammals have an extremely limited capacity for cardiac regeneration, contributing to mortality and morbidity from cardiac ...
M S W, Xiang, K, Kikuchi
openaire +2 more sources
MicroRNA Therapeutics for Cardiac Regeneration
Mini-Reviews in Medicinal Chemistry, 2015It is estimated that a typical myocardial infarction results in the loss of approximately one billion functional cardiomyocytes, which are replaced by a non-contractile fibrous scar, eventually leading to heart failure. The currently available surgical, drug, and device-based therapies cannot reverse the loss of functional myocardium, which is the ...
Zhiyong, Lei +2 more
openaire +2 more sources
Cardiotoxicity of anticancer treatments: Epidemiology, detection, and management
Ca-A Cancer Journal for Clinicians, 2016Giuseppe Curigliano +2 more
exaly