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Recent Patents on Regenerative Medicinee, 2011
This book chapter will explore the area of cardiac tissue engineering and biomaterials used for cardiac cell therapy. After describing the pathology of heart disease and presenting the motivation for pursuing tissue engineering for the heart, the chapter outlines some of the current clinical treatments used to correct the loss of function resulting ...
Devang Odedra +5 more
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This book chapter will explore the area of cardiac tissue engineering and biomaterials used for cardiac cell therapy. After describing the pathology of heart disease and presenting the motivation for pursuing tissue engineering for the heart, the chapter outlines some of the current clinical treatments used to correct the loss of function resulting ...
Devang Odedra +5 more
+5 more sources
Cardiac Ultrasonic Tissue Characterization
Hospital Practice, 1982This new variation on an old technique can actually define the physical state of a tissue--not merely visualize its size and motion. Clinical use awaits technologic refinements, but potential applications include noninvasive detection of amyloid protein, of myofibrillar disorientation characteristic of idiopathic hypertrophic subaortic stenosis, and of
J G, Miller, B E, Sobel
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Electromechanical Modelling of Cardiac Tissue
Journal of Biomechanics, 2008We present an electromechanical model of myocardium tissue, coupling finite elasticity, endowed with the capability of describing muscle contractions, with a FitzHugh–Nagumo type system, describing the electrical activity proper to excitable media. Here, we exploit a novel point of view which introduces the notion of active deformation as opposed to ...
C. CHERUBINI +3 more
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Tissue-Engineered Cardiac Constructs for Cardiac Repair
The Annals of Thoracic Surgery, 2011Several recent basic research studies have described surgical methods for cardiac repair using tissue cardiomyoplasty. This review summarizes recent advances in cardiac repair using bioengineered tissue from the viewpoint of the cardiac surgeon. We conclude that the results of many basic and preclinical studies indicate that bioengineered tissue can be
Shigeru, Miyagawa +4 more
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Whole Cardiac Tissue Bioscaffolds
2018Bioscaffolds serve as structures for cells in building complex tissues and full organs including heart. Decellularizing cardiac tissue results in cell-free extracellular matrix (ECM) that can be used as a cardiac tissue bioscaffold. The field of whole-heart tissue engineering has been revolutionized since the 2008 publication of the first perfusion ...
Karis R, Tang-Quan +3 more
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Cardiac muscle tissue engineering
IEEE Engineering in Medicine and Biology Magazine, 2003Cell-based therapy has emerged as a novel approach for replacing heart muscle, which is known not to regenerate after injury such as that caused by infarction or reconstructive surgery. Two types of cell-based therapies have been employed: injection of isolated cells or the implantation of in-vitro-grown cardiac muscle tissue equivalents In the first ...
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Cardiac endothelium and tissue growth
Progress in Cardiovascular Diseases, 1997In recent years, a number of peptide and nonpeptide signalling autacoids have been implicated in the regulation of cardiac myocyte growth as well as vasculogenesis and angiogenesis, and in the function of cardiac muscle following development. In this review, we first examine the evidence for a role for specific cytokines during cardiac ontogeny ...
J L, Balligand, R A, Kelly, T W, Smith
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Intramural resistivity of cardiac tissue
Medical and Biological Engineering and Computing, 1979The macroscopic resistivity of canine ventricular tissue has been measuredin vivo. Using a tetrapolar intramural electrode, values have been obtained for transmural resistivity as a function of depth, phase of the cardiac cycle and of the frequency of the applied current. The time course of resistivity owing to induced local ischaemia has been recorded.
A, van Oosterom +2 more
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Bioreactors for Cardiac Tissue Engineering
Advanced Healthcare Materials, 2018AbstractThe advances in biotechnology, biomechanics, and biomaterials can be used to develop organ models that aim to accurately emulate their natural counterparts. Heart disease, one of the leading causes of death in modern society, has attracted particular attention in the field of tissue engineering.
Jesus Paez‐Mayorga +7 more
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Hydrogels for cardiac tissue regeneration
Bio-Medical Materials and Engineering, 2008Our research is focused on the design of engineered biomaterials that can harness natural cellular and molecular healing pathways to enhance functional tissue regeneration. Two important considerations for tissue regeneration are induction and remodeling.
Keren, Shapira +4 more
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