Results 11 to 20 of about 103,495 (263)

Measurement of Cardiac Troponins [PDF]

Annals of Clinical Biochemistry: International Journal of Laboratory Medicine, 2001
The cardiac troponins form part of the regulatory mechanism for muscle contraction. Specific cardiac isoforms of cardiac troponin T and cardiac troponin I exist and commercially available immunoassay systems have been developed for their measurement. A large number of clinical and analytical studies have been performed and the measurement of cardiac ...
P O, Collinson, F G, Boa, D C, Gaze
openaire   +2 more sources

Value of Troponin Testing for Detection of Heart Disease in Previously Healthy Children

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Troponin levels are frequently obtained in pediatric patients, but the benefit remains unclear. Methods and Results This retrospective study included 1993 patients aged 0 to 21 years without history of cardiac disease in whom troponin levels ...
Audrey Dionne, John N. Kheir, Lynn A. Sleeper, Jesse J. Esch, Roger E. Breitbart   +4 more
doaj   +1 more source

Cardiac Troponins in Dogs and Cats [PDF]

Journal of Veterinary Internal Medicine, 2016
Abstract Cardiac troponins are sensitive and specific markers of myocardial injury. The troponin concentration can be thought of as a quantitative measure of the degree of injury sustained by the heart, however, it provides no information on the cause of injury or the mechanism of troponin release.
Langhorn, Rebecca, Willesen, Jakob
openaire   +4 more sources

Magnitude of troponin elevation in patients with biomarker evidence of myocardial injury: relative frequency and outcomes in a cohort study across a large healthcare system

BMC Cardiovascular Disorders, 2023
Background Serum troponin levels correlate with the extent of myocyte necrosis in acute myocardial infarction (AMI) and predict adverse outcomes.
Colleen K. McIlvennan, Manuel Urra, Laura Helmkamp, John C. Messenger, David Raymer, Karen S. Ream, J. Bradley Oldemeyer, Amrut V. Ambardekar, Kathleen Barnes, Larry A. Allen   +9 more
doaj   +1 more source

Troponin Levels in COVID-19 Patients and its Correlation with the Severity of Disease and Clinical Outcomes

Indian Journal of Medical Specialities, 2022
Introduction: The epidemic of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) has become a major health problem globally. The most common cardiac manifestation of COVID-19 infection is acute cardiac injury observed in patients even without ...
Vaibhav Shukla, Advait Munagekar
doaj   +1 more source

Metformin and high-sensitivity cardiac troponin I and T trajectories in type 2 diabetes patients: a post-hoc analysis of a randomized controlled trial

Cardiovascular Diabetology, 2022
Background Metformin has favorable effects on cardiovascular outcomes in both newly onset and advanced type 2 diabetes, as previously reported findings from the UK Prospective Diabetes Study and the HOME trial have demonstrated.
Johanna M. G. Stultiens, Wiebe M. C. Top, Dorien M. Kimenai, Philippe Lehert, Otto Bekers, Coen D. A. Stehouwer, Adriaan Kooy, Steven J. R. Meex   +7 more
doaj   +1 more source

Prognostic value of high-sensitive cardiac troponin-T in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention in Erbil cardiac center

Advanced Medical Journal, 2023
Background and objectives: Background and objectives: Patients with ST-segment elevation myocardial infarction have higher rates of major adverse cardiovascular events including deaths, and it is recommended that these patients should undergo primary ...
Hewa Mohammed Hamad Ameen, Mohammed Hasan Alwan   +1 more
doaj   +1 more source

Small Molecule RPI-194 Stabilizes Activated Troponin to Increase the Calcium Sensitivity of Striated Muscle Contraction

Frontiers in Physiology, 2022
Small molecule cardiac troponin activators could potentially enhance cardiac muscle contraction in the treatment of systolic heart failure. We designed a small molecule, RPI-194, to bind cardiac/slow skeletal muscle troponin (Cardiac muscle and slow ...
Zabed Mahmud, Svetlana Tikunova, Natalya Belevych, Cory S. Wagg, Pavel Zhabyeyev, Philip B. Liu, David V. Rasicci, Christopher M. Yengo, Gavin Y. Oudit, Gary D. Lopaschuk, Peter J. Reiser, Jonathan P. Davis, Peter M. Hwang, Peter M. Hwang   +13 more
doaj   +1 more source

Effects of high-intensity interval exercise on cardiac troponin elevation when comparing with moderate-intensity continuous exercise: a systematic review and meta-analysis [PDF]

PeerJ, 2023
Background This systematic review and meta-analysis aimed to compare the effects of high-intensity interval exercise (HIIE) with different recovery modes versus moderate-intensity continuous exercise (MICE) on cardiac troponin (cTn) elevation ...
Shuoqi Li, Shazlin Shaharudin, Rafel Cirer-Sastre, Feifei Li, Faizal Abdul Manaf, Mohd Faiz Mohd Shukri   +5 more
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Prognostic value of troponin I after coronary artery bypass grafting (AMIRI-CABG study)

Вестник трансплантологии и искусственных органов, 2021
In 2017, the European Society of Cardiology outlined the importance of the problem of diagnosing myocardial ischemia-reperfusion injury following coronary artery bypass grafting.
N. S. Bunenkov, V. V. Komok, S. A. Bely, A. V. Sokolov, V. I. Lukashenko, A. S. Nemkov, G. G. Khubulava   +6 more
doaj   +1 more source