Results 131 to 140 of about 510,668 (221)

The Psychosocial Impact of Receiving Whole Genome and Whole Exome Sequencing Results in Adults: A Systematic Review

Journal of Genetic Counseling, Volume 35, Issue 5, October 2026.
ABSTRACT The expanding use of whole genome sequencing (WGS) and whole exome sequencing (WES) underscores the need to better understand the psychosocial impact of receiving a broader range of potential results than those generated by other types of genetic testing.
Monica Albu, Andrada Ciucă, Ramona Moldovan   +2 more
wiley   +1 more source

MR Derived Cardiac Metabolism Changes in Patients With Obesity and Diabetes: Knowledge Discovery Via Bayesian Networks and Random Forest Classification

NMR in Biomedicine, Volume 39, Issue 10, October 2026.
Characterization of healthy vs. diabetic (73:67$$ 73:67 $$) random forest classification group and its Bayesian network learned through NOTEARS structure algorithm on multi‐modal data. Shown computed SHapley Additive exPlanation (SHAP) values for various features.
Ina Hanninger, Andrej Krafčík, Eylem Levelt, Jennifer J Rayner, Chistopher T Rodgers, Stefan Neubauer, Vicente Grau, Oliver J Rider, Ladislav Valkovič   +8 more
wiley   +1 more source

The role of macrophage migration inhibitory factor (MIF) in the pathogenesis and progression of cardiovascular disease

British Journal of Pharmacology, Volume 183, Issue 19, Page 5732-5751, October 2026.
Abstract Cardiovascular disease (CVD) remains the leading global cause of death, driven by complex mechanisms, in which chronic inflammation plays a central role. Inflammatory pathways contribute to all stages of CVD, from endothelial dysfunction and plaque formation to erosion, rupture and myocardial injury.
Shreya Mahabhashyam, James Harris, Jürgen Bernhagen, Antony Vinh, Katrina M. Mirabito Colafella   +4 more
wiley   +1 more source

From Real World Data to Real Impact: A Co‐Medication Framework for Lung Cancer to Advance DDI Assessment and Patient‐Centric Drug Development

Clinical and Translational Science, Volume 19, Issue 10, October 2026.
ABSTRACT Lung cancer predominantly affects older adults who already experience comorbidities and are at increased risk of drug–drug interactions (DDIs) due to polypharmacy. Traditional DDI assessments often do not fully capture complex co‐medication patterns observed in real‐world practice due to the risk of introducing confounding factors.
Mareena Biju, HeeJae Choi, Shilpa Madari, Annie Carlisle, Ashish Sharma, Christina Kunz, Fenglei Huang   +6 more
wiley   +1 more source

Cardio-oncology: the role of big data.

, 2017
Despite its challenges, a big data approach offers a unique opportunity within the field of cardio-oncology. A pharmacovigilant approach using large data sets can help characterize cardiovascular toxicities of the rapidly expanding armamentarium of ...
Mandawat, Anant, Francis, Sanjeev A, Williams, Andrew E   +2 more
core   +1 more source

Cancer, Inflammation, and Thrombosis: Drivers of Atrial Fibrillation in Oncology Patients

Clinical and Applied Thrombosis/Hemostasis
Background Atrial fibrillation (AF) is a frequent and serious cardiovascular complication in oncology patients, driven by shared pathophysiological mechanisms of inflammation, thrombosis, and cardiac remodeling.
Ameer Awashra MD, Hamza A. Abdul-Hafez MD, Moaath Swalha MD, Enas Samara MD, Bayan Mahafdah MD, Mohammed AbuBaha MD, Ahmed Emara MD, Anwar Zahran MD, Mohamed S. Elgendy MD, Abdalhakim Shubietah MD   +9 more
doaj   +1 more source

Glycemic and Renal Effects of SGLT2 Inhibitors in Monogenic Diabetes: A Real‐World National Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 10, Page 9633-9643, October 2026.
ABSTRACT Aims Evidence regarding the efficacy and safety of sodium–glucose cotransporter 2 inhibitors (SGLT2i) in monogenic diabetes is limited. We evaluated real‐world metabolic, renal, and safety outcomes of SGLT2i therapy in adults with monogenic diabetes.
Estelle Audrain, Pierre Bel Lassen, Christine Bellanné‐Chantelot, Marie Christine Vantyghem, Hippolyte Dupuis, Tiphaine Vidal‐Trecan, Nicolas Chevalier, Danièle Dubois‐Laforgue, Sophie Lamothe, Camille Vatier, Orianne Villard, René Valéro, Claire Briet, Corinne Vigouroux, Cécile Ciangura, Chloé Amouyal   +15 more
wiley   +1 more source

Clonal Hematopoiesis and CAR T Cell Therapy: From Biological Crosstalk to Clinical Implications

International Journal of Laboratory Hematology, Volume 48, Issue 5, Page 961-971, October 2026.
ABSTRACT Clonal hematopoiesis (CH) is increasingly recognized as a significant biological phenomenon in aging and cancer, marked by the expansion of hematopoietic stem and progenitor cells harboring somatic mutations in genes associated with myeloid neoplasms.
Wei Du, Shunsuke Koga, Guang Yang, Saar Gill, Adam Bagg   +4 more
wiley   +1 more source

Wearable Electronic Monitoring of Vital Signs in Hospitalised Adults: A Nursing Focused Scoping Review of Clinical, Economic and Implementation Outcomes

Journal of Advanced Nursing, Volume 82, Issue 10, Page 9061-9111, October 2026.
ABSTRACT Aim To synthesise evidence on wearable devices for continuous vital signs monitoring in adult hospital inpatients, focusing on clinical effectiveness, nursing perspectives, workflow impact, patient experience and resource implications. Design Scoping review.
Sian Myfanwy Shaw, Sophie Bethan Shaw, Gillian Janes   +2 more
wiley   +1 more source

The gut-heart axis in cardio-oncology. [PDF]

Cardiovasc Res
Chan NSL, Cross C, Bowen J, Prestidge C, Ryan FJ, Dorraki M, Liyanage S, Sharma S, Pathy R, Bursill CA, Psaltis PJ, Marques FZ, Wardill HR, Joyce P.   +13 more
europepmc   +1 more source