Results 11 to 20 of about 38,754 (240)
Cross-species complementation of bacterial- and eukaryotic-type cardiolipin synthases [PDF]
Microbial Cell, 2017 The glycerophospholipid cardiolipin is a unique constituent of bacterial and mitochondrial membranes. It is involved in forming and stabilizing high molecular mass membrane protein complexes and in maintaining membrane architecture.
Petra Gottier +4 more
doaj +3 more sources
Cardiolipin and the Nlrp3 Inflammasome [PDF]
Cell Metabolism, 2013 The Nlrp3 inflammasome is a key controller of the proinflammatory cytokine IL-1β. Iyer and colleagues (2013) demonstrate that Nlrp3 activators promote an interaction between cardiolipin in mitochondria and Nlrp3. Cardiolipin is thus a hydrophobic danger signal that, upon translocation to the outer mitochondrial membrane, activates Nlrp3, promoting ...
O’Neill, Luke A.J., O\u27NEILL, LUKE
openaire +5 more sources
Structural insights into cardiolipin replacement by phosphatidylglycerol in a cardiolipin-lacking yeast respiratory supercomplex [PDF]
Nature Communications, 2023 Cardiolipin is a hallmark phospholipid of mitochondrial membranes. Despite established significance of cardiolipin in supporting respiratory supercomplex organization, a mechanistic understanding of this lipid-protein interaction is still lacking.
Corey F. Hryc +9 more
doaj +2 more sources
Studies of the cardiolipin interactome
Progress in Lipid Research, 2022 Cardiolipin (CL) is a unique phospholipid that is fundamental to the structure and function of the highly curved cristae membranes of mitochondria. Given its distinctive cone-shaped molecular architecture, CL induces negative membrane curvature in a bilayer setting.
Colin A, Fox, Robert O, Ryan
core +5 more sources
The cardiolipin analogues of Archaea [PDF]
Biochimica et Biophysica Acta (BBA) - Biomembranes, 2009 The present article reviews studies of the structure and functional roles of the cardiolipin analogues of extremely halophilic prokaryotes belonging to the Archaea domain. Analogies and differences between the archaeal bisphosphatidylglycerol and the mitochondrial cardiolipin are presented. Furthermore the structure of archaeal glycophospholipid dimers
CORCELLI, Angela
openaire +5 more sources
Phase Behavior Of Cardiolipin [PDF]
, 2012 Cardiolipin is a phospholipid with negatively charged headgroups. This lipid is structurally unique in its quadruple-chained configuration and functionally unique in its nearly exclusive involvement in the cellular energy production processes.
Chen, Yi-fan
core +6 more sources
, 2022 Restoring innate apoptosis and simultaneously inhibiting metastasis by a molecular drug is an effective cancer therapeutic approach. Herein, a large rigid and V-shaped NIR-II dye, DUT850, is rationally designed for potential cardiolipin (CL)-targeted ...
Dandan Ma (561251) +8 more
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Cardiolipin synthesizing enzymes form a complex that interacts with cardiolipin-dependent membrane organizing proteins. [PDF]
, 2018 The mitochondrial glycerophospholipid cardiolipin plays important roles in mitochondrial biology. Most notably, cardiolipin directly binds to mitochondrial proteins and helps assemble and stabilize mitochondrial multi-protein complexes.
Vissa, Adriano +9 more
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Cardiolipin stabilizes respiratory chain supercomplexes
, 2021 Cardiolipin stabilized supercomplexes of Saccharomyces cerevisiae respiratory chain complexes III and IV (ubiquinol:cytochrome c oxidoreductase and cytochrome c oxidase, respectively), but was not essential for their formation in the inner mitochondrial ...
Hunte, Carola +6 more
core +2 more sources
, 2023 In clinical settings, the benefit of statin for stroke is debatable as regular statin users may suffer from myalgia, statin-associated myopathy (SAM), and rarely rhabdomyolysis.
Swapnil Raut +29 more
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