Results 21 to 30 of about 39,995 (259)

Cardiolipin Alterations during Obesity: Exploring Therapeutic Opportunities

open access: yesBiology, 2022
Cardiolipin is a specific phospholipid of the mitochondrial inner membrane that participates in many aspects of its organization and function, hence promoting proper mitochondrial ATP production.
Alexandre Prola, Fanny Pilot-Storck
doaj   +1 more source

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

Dynamic simulation of cardiolipin remodeling: greasing the wheels for an interpretative approach to lipidomics[S]

open access: yesJournal of Lipid Research, 2010
Cardiolipin is a class of mitochondrial specific phospholipid, which is intricately involved in mitochondrial functionality. Differences in cardiolipin species exist in a variety of tissues and diseases.
Michael A. Kiebish   +9 more
doaj   +1 more source

Absence of Cardiolipin From the Outer Leaflet of a Mitochondrial Inner Membrane Mimic Restricts Opa1-Mediated Fusion

open access: yesFrontiers in Molecular Biosciences, 2021
Cardiolipin is a tetra-acylated di-phosphatidylglycerol lipid enriched in the matrix-facing (inner) leaflet of the mitochondrial inner membrane. Cardiolipin plays an important role in regulating mitochondria function and dynamics.
Yifan Ge   +9 more
doaj   +1 more source

Thematic Review Series: Glycerolipids. Cardiolipin synthesis for the assembly of bacterial and mitochondrial membranes*

open access: yesJournal of Lipid Research, 2008
In this article, the formation of prokaryotic and eukaryotic cardiolipin is reviewed in light of its biological function. I begin with a detailed account of the structure of cardiolipin, its stereochemistry, and the resulting physical properties, and I ...
Michael Schlame
doaj   +1 more source

Phase Behavior Of Cardiolipin [PDF]

open access: yes, 2012
Cardiolipin is a phospholipid with negatively charged headgroups. This lipid is structurally unique in its quadruple-chained configuration and functionally unique in its nearly exclusive involvement in the cellular energy production processes.
Chen, Yi-fan
core   +5 more sources

Clarifying the Roles of Cardiolipin [PDF]

open access: yesBiophysical Journal, 2014
Cardiolipins (CL) are uniquely structured double lipids that are universally found in membranes which couple electron transport and phosphorylation. The proposed roles of CL in these membranes include mainly two aspects: the effects on the structure and dynamics of the membranes' lipid component and the interplay with membrane-associated proteins.
Pöyry, Sanja   +7 more
openaire   +1 more source

Cardiolipin Interactions with Proteins [PDF]

open access: yesBiophysical Journal, 2015
Cardiolipins (CL) represent unique phospholipids of bacteria and eukaryotic mitochondria with four acyl chains and two phosphate groups that have been implicated in numerous functions from energy metabolism to apoptosis. Many proteins are known to interact with CL, and several cocrystal structures of protein-CL complexes exist.
Planas-Iglesias, Joan   +5 more
openaire   +2 more sources

Structure of Cardiolipin [PDF]

open access: yesNature, 1958
PANGBORN1 considered that the glycerylglycero-phosphate skeleton of cardiolipin contained three phosphoric acid and four glycerol residues (I), the six available hydroxyl groups in this structure being esterified with unsaturated fatty acids in the intact phospholipid.
openaire   +2 more sources

Cardiolipin Strongly Inhibits the Leakage Activity of the Short Antimicrobial Peptide ATRA-1 in Comparison to LL-37, in Model Membranes Mimicking the Lipid Composition of Staphylococcus aureus

open access: yesMembranes, 2023
Cardiolipin is one of the main phospholipid components of Staphylococcus aureus membranes. This lipid is found at varying concentrations in the bilayer, depending on the growth stage of the bacteria, and as a response to environmental stress. Cardiolipin
Nathalia Calderón-Rivera   +5 more
doaj   +1 more source

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